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ClinicalTrials.gov public records Last synced Oct 17, 2026, 1:01 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 265–288 of 1,088 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol Addiction Clear all
Recruiting Not applicable Interventional

Combining a Smartphone App With Medications to Manage Heavy Drinking

NCT06303778
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Stand Down mobile app, Standard Care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
15
States / cities
Phoenix, Arizona • Fayetteville, Arkansas • Washington D.C., District of Columbia + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 1 Interventional Results available

ED Initiated Oral Naltrexone for AUD

NCT04817410
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Emergency Department Initiated Oral Naltrexone
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Oct 17, 2026, 1:01 AM EDT
Not listed Phase 2Phase 3 Interventional

A Comparison of Adolescent Group Therapy and Transitional Family Therapy for Adolescent Alcohol and Drug Abusers

NCT00484367
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence, Cannabis Abuse, Cannabis Dependence, Other Substance Abuse
Interventions
Adolescent group therapy, Transitional family therapy
Behavioral
Lead sponsor
The Morton Center, Inc.
Other
Eligibility
13 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2012
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 26, 2011 · Synced Oct 17, 2026, 1:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits

NCT00001500
View directory record Official record
Conditions
Acquired Immunodeficiency Syndrome, Alcoholism, HIV Infection, Neoplasm, Smoking
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
4,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional

Affective Modulation of Positivity for Alcohol Use Disorder

NCT04278365
View directory record Official record
Conditions
Anxiety, Depression, Alcohol Use Disorder
Interventions
Positive affect training
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 1, 2020 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional Results available

A Pilot Clinical Trial of Varenicline as a Treatment for Alcohol Dependence

NCT01011907
View directory record Official record
Conditions
Substance Dependence
Interventions
varenicline, placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 75 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Emeryville, California
Source: ClinicalTrials.gov public record
Updated Feb 25, 2013 · Synced Oct 17, 2026, 1:01 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Pharmaceutically-Enhanced Reinforcement for Reduced Alcohol and Smoking

NCT05181891
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), Nicotine Use Disorder
Interventions
Contingency Management, Non-contingent control
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional

Mindfulness for Alcohol Abusing Offenders

NCT03883646
View directory record Official record
Conditions
Alcohol Abuse, Criminal Behavior
Interventions
Mindfulness, Relapse Prevention
Behavioral
Lead sponsor
The Mind Research Network
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
392 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 2 Interventional

Couples Therapy for Alcoholic Patients

NCT01659957
View directory record Official record
Conditions
Alcoholism
Interventions
Group Couples Counseling, One-on-One Couples Counseling
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
18 Years to 65 Years
Enrollment
285 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 23, 2015 · Synced Oct 17, 2026, 1:01 AM EDT
Not listed Phase 2 Interventional

Project RAP: Reaching Adolescents for Prevention

NCT00183157
View directory record Official record
Conditions
Alcohol Related Morbidity, Alcohol Dependence
Interventions
Brief Motivational Intervention, Assessment and list of resources, Referral to Community Resources
Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
14 Years to 21 Years
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2009 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 2 Interventional Results available

Modafinil for the Treatment of Alcohol Use Disorders

NCT03424681
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Modafinil, Placebo
Drug · Other
Lead sponsor
The Mind Research Network
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 26, 2020 · Synced Oct 17, 2026, 1:01 AM EDT
Terminated Phase 1 Interventional Results available

Pitolisant Effects on Alcohol Self-Administration in Heavy Drinkers

NCT04596267
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Drinking
Interventions
Pitolisant, Placebo
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years to 55 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 4, 2023 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Remote Brief Intervention and Referrals to Treatment Service for Alcohol

NCT02622984
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence
Interventions
RBIRT, SBIRT
Behavioral
Lead sponsor
Polaris Health Directions
Industry
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 17, 2026, 1:01 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

mHealth App for Changing Alcohol Use in Alaska Native American Indian People

NCT05326438
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
CIRCLE mHealth app
Behavioral
Lead sponsor
Southcentral Foundation
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Oct 17, 2026, 1:01 AM EDT
Terminated Not applicable Interventional

A Critical Illness Recovery Navigator for Alcohol

NCT03059082
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Recovery Navigator on an as needed basis up to 6 months, Recovery Navigator prior to hospital discharge, No interaction with Recovery Navigator
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 21, 2019 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 2 Interventional

Comparing Gabapentin and Lorazepam for Treating Alcohol Withdrawal

NCT00011297
View directory record Official record
Conditions
Alcoholism
Interventions
gabapentin (Neurontin), lorazepam (Ativan)
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 70 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2005
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 23, 2006 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional Results available

Brief Restructuring Intervention Following Trauma Exposure

NCT02808468
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Alcohol Use Disorders
Interventions
Brief Cognitive Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Oct 17, 2026, 1:01 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Ambulatory Alcohol Detoxification With Remote Monitoring

NCT03582150
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Remote Monitoring with Ambulatory Detox
Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 16, 2022 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 2 Interventional

Screening and Brief Intervention in the ED Among Mexican-origin Young Adults

NCT02056535
View directory record Official record
Conditions
Problem Drinking, Alcohol Dependence
Interventions
Brief Motivational Intervention
Behavioral
Lead sponsor
Public Health Institute, California
Other
Eligibility
18 Years to 30 Years
Enrollment
698 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2014 · Synced Oct 17, 2026, 1:01 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

The Effects of Exenatide, a GLP-1 Agonist, on Alcohol Self-Administration in Heavy Drinkers

NCT03645408
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Exenatide, Sham injection
Drug · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 9, 2022 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 1 Interventional Results available

Kappa-PET Imaging and Naltrexone in Alcohol Drinking Behaviors

NCT01625611
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Naltrexone
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 50 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 10, 2022 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Phase 2 Interventional

Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1

NCT00142844
View directory record Official record
Conditions
Alcohol-Related Disorders, Alcoholism, Cocaine-Related Disorders
Interventions
Naltrexone, Disulfiram, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 17, 2026, 1:01 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study

NCT06687525
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use, Alcoholism, Binge Drinking
Interventions
Not listed
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years to 30 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Champaign, Illinois
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 17, 2026, 1:01 AM EDT
Completed Not applicable Interventional Results available

Smartphone Based Continuing Care for Alcohol

NCT02681406
View directory record Official record
Conditions
Alcohol Abuse
Interventions
ACHESS, TMC
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 9, 2022 · Synced Oct 17, 2026, 1:01 AM EDT