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ClinicalTrials.gov public records Last synced Oct 17, 2026, 2:35 AM EDT

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Showing 313–336 of 1,088 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol Addiction Clear all
Completed Not applicable Interventional Results available

Study of the Effects of Motivational Enhancement Therapy on Alcohol Use in Chronic Hepatitis C Patients

NCT00596960
View directory record Official record
Conditions
Alcohol Dependence, Chronic Hepatitis C
Interventions
Motivational Enhancement Therapy (MET), Health education
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Minneapolis, Minnesota • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 28, 2014 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Phase 2 Interventional Results available

Study of the Medication Prazosin for Alcohol Dependence

NCT00762710
View directory record Official record
Conditions
Alcoholism
Interventions
Prazosin medication, Placebo medication
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 17, 2026, 2:35 AM EDT
Recruiting Phase 2 Interventional

The Role of Brief Potent Glutamatergic Modulation in Addressing Problem Drinking

NCT04084860
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
CI-581a, CI-581b, MBRP, MET
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 70 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 17, 2026, 2:35 AM EDT
Terminated Phase 2 Interventional Results available

HLAB-002 of ANS-6637 for Alcohol Use Disorder

NCT03970109
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
ANS-6637, Placebo oral tablet
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
3
States / cities
New Haven, Connecticut • Providence, Rhode Island • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 29, 2024 · Synced Oct 17, 2026, 2:35 AM EDT
Not listed Not applicable Interventional

Divalproex Sodium for Mood Swings and Alcohol Use Following Head Injury.

NCT01326663
View directory record Official record
Conditions
Veterans, TBI, Alcoholism, Irritable Mood
Interventions
Medication Trial
Drug
Lead sponsor
Paul Saenger
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 7, 2012 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Phase 4 Interventional Results available

High Dose Vitamin B1 to Reduce Abusive Alcohol Use

NCT00680121
View directory record Official record
Conditions
Alcoholism
Interventions
Benfotiamine, Placebo
Drug
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2014 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Phase 2 Interventional

Sertraline and Naltrexone for Alcohol Dependence

NCT00000440
View directory record Official record
Conditions
Alcoholism
Interventions
naltrexone (Revia), sertraline (Zoloft)
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 55 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2002
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Phase 2 Interventional Results available

HBPL Study of the Impact of the NK1 Antagonist Aprepitant

NCT01176591
View directory record Official record
Conditions
Cocaine Dependence, Alcohol Dependence
Interventions
Placebo session 1, Aprepitant session 2, Placebo session 1, Placebo session 2
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2020 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Web Intervention for Concerned Partners to Prevent Service Member Alcohol Abuse Abuse

NCT02073825
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Web Brief Intervention (WBI)
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2017 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Evaluation of the Empower Neuromodulation System in AUD Patients

NCT03983317
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Empower Neuromodulation System
Device
Lead sponsor
Theranova, L.L.C.
Industry
Eligibility
21 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Not applicable Interventional

CM Treatment for Alcohol Dependence Using New Technology

NCT02143037
View directory record Official record
Conditions
Alcohol Use Disorder, Contingency Management
Interventions
prize contingency management for attending treatment, usual care
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Bridgeport, Connecticut • Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 17, 2019 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Tailored Tobacco Quitline for Rural Veterans

NCT01592695
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Nicotine replacement therapy - transdermal nicotine patch, Tailored behavioral intervention, Tobacco quit line referral, Nicotine replacement therapy - nicotine gum, Nicotine replacement therapy - nicotine lozenge, Bupropion Sustained Release, Varenicline, Combination pharmacotherapy - transdermal nicotine patch + nicotine gum, Combination pharmacotherapy - transdermal nicotine patch + nicotine lozenge, Combination pharmacotherapy - transdermal nicotine patch + bupropion, Alcohol use risk reduction, Behavioral activation for the treatment of depression, Behavioral management of post-cessation weight gain
Drug · Behavioral
Lead sponsor
Iowa City Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 99 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 2, 2019 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

ALK33-001: A Study of RDC-0313 Administered to Healthy Adults

NCT00800319
View directory record Official record
Conditions
Alcohol Dependence
Interventions
RDC-0313, Placebo
Drug
Lead sponsor
Alkermes, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 22, 2011 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Not applicable Interventional Results available

Web-based Intervention to Reduce Alcohol Use in Veterans With Hepatitis C

NCT01707030
View directory record Official record
Conditions
Hepatitis C, Alcohol Abuse
Interventions
Web-Based Brief Alcohol Intervention, Usual Care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
Palo Alto, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 17, 2026, 2:35 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

A Study of Pleiotropic Pioglitazone Effects on the Alcoholic Lung (APPEAL Study)

NCT03060772
View directory record Official record
Conditions
Alcoholism
Interventions
Pioglitazone
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Not applicable Interventional

Phased Treatment for Social Anxiety Disorder and Coping Behaviors in a Medical Setting

NCT00862212
View directory record Official record
Conditions
Social Anxiety Disorder, Alcohol Use Disorders
Interventions
Brief Alcohol Intervention
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Minneapolis, Minnesota • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 23, 2013 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

[C-11]NOP-1A and Alcohol Use Disorder

NCT03448016
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
[C-11], NOP-1A
Radiation · Drug
Lead sponsor
Rajesh Narendran
Other
Eligibility
18 Years to 55 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Intervention for Teen Drinking in the ER

NCT01229748
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Standard Care, Multidimensional Family Therapy, Family Motivational Interviewing Intervention
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 18 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
3
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 1, 2015 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Phase 1 Interventional

Ketamine for Depression and Alcohol Dependence

NCT01551329
View directory record Official record
Conditions
Depression, Alcohol Dependence
Interventions
Ketalar (ketamine)
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Phase 4 Interventional Results available

Zonisamide vs. Placebo in the Treatment of Alcohol Dependence

NCT00595556
View directory record Official record
Conditions
Alcoholism, Alcohol Abuse, Alcohol Dependence
Interventions
zonisamide, Placebo
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 15, 2010 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Not applicable Interventional Results available

LINK: Aftercare Monitoring Project

NCT00265512
View directory record Official record
Conditions
Alcohol Dependence, Drug Dependence
Interventions
Telephone Case Monitoring, Continuing Care as Usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
667 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
3
States / cities
Palo Alto, California • Topeka, Kansas • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Oct 17, 2026, 2:35 AM EDT
Completed Phase 4 Interventional Results available

Pharmacogenetic Response to Naltrexone For Alcohol Dependence

NCT00831272
View directory record Official record
Conditions
Alcohol Dependence
Interventions
naltrexone, Placebo
Drug
Lead sponsor
David Oslin
Other
Eligibility
18 Years and older
Enrollment
221 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
4
States / cities
Danville, Pennsylvania • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 11, 2017 · Synced Oct 17, 2026, 2:35 AM EDT
Not yet recruiting Not applicable Interventional

Social Identity Mapping for Adolescent Recovery

NCT07474207
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
SIM-AiR
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Years to 19 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Oct 17, 2026, 2:35 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Couples-based Behavioral Psychotherapy for Male Patients With Posttraumatic Stress Disorder and Alcohol Dependence

NCT00622921
View directory record Official record
Conditions
PTSD, Alcohol Dependence
Interventions
Couples-based behavioral psychotherapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Oct 17, 2026, 2:35 AM EDT