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ClinicalTrials.gov public records Last synced Oct 17, 2026, 5:01 PM EDT

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Showing 481–504 of 1,088 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol Addiction Clear all
Completed Phase 2Phase 3 Interventional

Integrated Digital Intervention for Alcohol Use Disorder

NCT05748639
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Mobile health application, Medical Management
Other
Lead sponsor
Quit Genius
Industry
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 1

NCT00249496
View directory record Official record
Conditions
Alcohol Use, Drug Use, Risk Behavior, Sexual Behavior
Interventions
Contingency management, Employment Only
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Oct 17, 2026, 5:01 PM EDT
Recruiting Phase 4 Interventional

Naltrexone in AUD Reward Drinkers

NCT05028062
View directory record Official record
Conditions
Alcohol Use Disorder, Alcoholism
Interventions
XR-NTX 380 mg, intramuscular injection, Medical Management, Placebo intramuscular injection
Drug · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 17, 2026, 5:01 PM EDT
Recruiting Phase 4 Interventional

Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use Disorder

NCT06269627
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Acamprosate calcium, Placebo
Drug · Other
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Phase 2 Interventional

A Therapeutic Workplace for Alcohol Dependence

NCT00183144
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Contingency management
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 19, 2010 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Phase 2 Interventional Results available

Ibudilast for the Treatment of Alcohol Use Disorder

NCT03594435
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Ibudilast, Placebo oral capsule
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2024 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Fish Oil vs. Placebo on Subjective Effects of Alcohol

NCT03010917
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Fish Oil with ethanol and placebo ethanol infusions, Placebo with ethanol and placebo ethanol infusions
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 22, 2022 · Synced Oct 17, 2026, 5:01 PM EDT
Recruiting Not applicable Interventional

TMS to Improve Recovery Outcomes Among Patients With Opioid Use Disorder (OUD) and Alcohol Use Disorder (AUD)

NCT07171359
View directory record Official record
Conditions
Alcohol Use Disorder, Opioid Use Disorder
Interventions
TMS Low-Dose, TMS High-Dose
Device
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 17, 2026, 5:01 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Intravenous Acetate as an Adjunctive Treatment for Alcohol Withdrawal in Hospitalized Patients

NCT07810946
View directory record Official record
Conditions
Alcohol Withdrawal, Alcohol Abstinence, Alcohol Use Disorder
Interventions
Sodium Acetate, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Efficacy and Mechanisms of CBT4CBT for Alcohol Use Disorders

NCT02742246
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Individual clinician-provided CBT, CBT4CBT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
Bridgeport, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Group Therapies for Reducing HIV-risk Behavior in Women Who Have Survived Childhood Sexual Abuse

NCT00220597
View directory record Official record
Conditions
Alcoholism, Child Abuse, Sexual, Sexual Abuse, Sexual Behavior, Sexually Transmitted Diseases, Viral
Interventions
Trauma-focused group therapy
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2004
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 3, 2013 · Synced Oct 17, 2026, 5:01 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Does Oxytocin Alter Tolerance to or Motivation for Alcohol

NCT05312008
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Intranasal oxytocin, Intranasal placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 60 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Not applicable Interventional

Ambivalence Model of Craving: Re-examining the Drinking-craving Relationship

NCT01883089
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Motivational Enhancement Therapy
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Not applicable Interventional Results available

Stress, Emotion Regulation, and Alcohol in Women Veterans

NCT04393623
View directory record Official record
Conditions
Alcohol Use Disorder, Post Traumatic Stress Disorder
Interventions
Cognitive Reappraisal, Psychoeducation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older · Female only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Leeds, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Phase 3 Interventional

Quetiapine Fumarate (Seroquel) for the Treatment of Alcohol Dependence.

NCT00124059
View directory record Official record
Conditions
Alcoholism
Interventions
Seroquel, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 6, 2015 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Cannabinoid Receptor Function & Alcoholism

NCT00624715
View directory record Official record
Conditions
Alcoholism
Interventions
THC, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 30 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 11, 2022 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Phase 2 Interventional

Alkontrol-herbal Effects on Alcohol Drinking

NCT03099590
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Use Disorder, Alcohol Abstinence
Interventions
kudzu extract, puerarin, Placebo control
Dietary Supplement
Lead sponsor
Mclean Hospital
Other
Eligibility
21 Years to 60 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Guanfacine to Reduce Relapse Risk in Women With Alcohol Use Disorder (AUD)

NCT03137082
View directory record Official record
Conditions
Alcohol Abstinence
Interventions
Guanfacine XR 3mgs/daily, Placebo (for guanfacine)
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Oct 17, 2026, 5:01 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Brief Integrative Alcohol Interventions for Adolescents

NCT01427465
View directory record Official record
Conditions
Alcohol Abuse, Drug Abuse
Interventions
Brief Prevention Program Using Positive Image
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 22, 2011 · Synced Oct 17, 2026, 5:01 PM EDT
Active, not recruiting Not applicable Interventional

Behavioral Economic and Wellness-based Approaches for Reducing Alcohol Use and Consequences Among Emerging Adults

NCT04776278
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Brief Alcohol Intervention (BAI), Substance-free Activity Session (SFAS), Relaxation Training (RT), Education Control
Behavioral · Other
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 29 Years
Enrollment
525 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pilot Study on Training Emerging Adults Skills in Navigating College

NCT05560425
View directory record Official record
Conditions
Alcohol Abuse, Cognitive Deficit in Attention
Interventions
Koru Mindfulness (KM) Training, Navigating College (NC) Training
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 19 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 17, 2026, 5:01 PM EDT
Completed Phase 4 Interventional Results available

Adjunctive Topiramate for Treatment of Alcohol Dependence in Patients With Bipolar Disorder

NCT00572117
View directory record Official record
Conditions
Bipolar Disorder, Alcoholism, Alcohol Dependence
Interventions
Topiramate
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2017 · Synced Oct 17, 2026, 5:01 PM EDT
Enrolling by invitation Not applicable Interventional

Acceptability and Feasibility Study of Non-alcoholic Beverages

NCT07451574
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Non-alcoholic beer, Sparkling water
Other
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 17, 2026, 5:01 PM EDT
Not listed Not applicable Interventional

PTSD, AUD, and Interpersonal Conflict: Within-person Associations

NCT04552782
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Alcoholism
Interventions
Alcohol CBM, PTSD CBM, Alcohol Sham, PTSD Sham
Behavioral
Lead sponsor
University of South Dakota
Other
Eligibility
18 Years to 60 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
Bay Pines, Florida • Sioux Falls, South Dakota • Vermillion, South Dakota
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Oct 17, 2026, 5:01 PM EDT