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ClinicalTrials.gov public records Last synced Oct 18, 2026, 5:22 PM EDT

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Showing 817–840 of 1,088 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol Addiction Clear all
Completed No phase listed Observational Accepts healthy volunteers

Examining Common Substrates of Eating and Alcohol Use Disorders

NCT01172210
View directory record Official record
Conditions
Bulimia Nervosa, Alcohol Use Disorders
Interventions
Not listed
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 45 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2014 · Synced Oct 18, 2026, 5:22 PM EDT
Active, not recruiting No phase listed Observational

Observational Pilot Study to Explore the Social and Health Impacts of a New Model of Care in Oregon: Psilocybin Services on Alcoholism

NCT07189988
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
psilocybin
Other
Lead sponsor
Healing Advocacy Fund
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Not applicable Interventional

Mindfulness-Based Relapse Prevention for Alcohol Use Disorders in Remission

NCT02147483
View directory record Official record
Conditions
Alcohol Use Disorders
Interventions
Mindfulness Based Relapse Prevention, Treatment as usual
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
21 Years to 80 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Oct 18, 2026, 5:22 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Neural Correlates During Alcohol Intoxication

NCT06118580
View directory record Official record
Conditions
Alcohol Use Disorder, Intermittent Explosive Disorder
Interventions
Alcohol (Ethanol), Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 55 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Phase 2 Interventional Results available

NAC for Treating Comorbid PTSD and SUD

NCT02911285
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Alcohol Use Disorder (AUD), Substance Use Disorder (SUD)
Interventions
N-acetylcysteine, Placebo, Cognitive behavioral therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Oct 18, 2026, 5:22 PM EDT
Recruiting Not applicable Interventional

Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder

NCT06518785
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Low Intensity Focused Ultrasound
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Phase 2 Interventional

Aftercare for Adolescents Treated for Alcohol Abuse and Dependence

NCT00561041
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Brief phone aftercare intervention, individual aftercare therapy
Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
13 Years to 18 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 20, 2007 · Synced Oct 18, 2026, 5:22 PM EDT
Withdrawn Phase 2 Interventional

Development of a Selective ALDH2 Inhibitor to Treat AUD

NCT04311294
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
ANS-6637 Low Dose, ANS-6637 High Dose, Matched Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 25, 2021 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Effects of Cannabidiol in Alcohol Use Disorder

NCT03252756
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Placebo, Phytocannabinoid cannabidiol (CBD)
Other · Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 18, 2026, 5:22 PM EDT
Recruiting Phase 2 Interventional

Donepezil and Cognitive Training for Alcohol Use Disorder (AUD)

NCT05042102
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Donepezil + Cognitive remediation therapy (CRT), Donepezil + Placebo CRT, Placebo medication + Cognitive remediation therapy (CRT), Placebo medication + Placebo CRT
Combination Product
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years to 80 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 18, 2026, 5:22 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Apremilast for Alcohol Use Disorder Treatment in Women and Men

NCT06324435
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Apremilast
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Cortical rTMS as a Tool to Change Brain Reactivity to Alcohol Cues

NCT02939313
View directory record Official record
Conditions
Alcohol Dependance
Interventions
medial prefrontal cortex, dorsolateral prefrontal cortex, sham
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 40 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Based Contingency Management for Adolescent Alcohol Abuse

NCT00595478
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Motivational Enhancement Therapy (MET)/CBT+CM, Motivational Enhancement Therapy (MET)/CBT
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Oct 18, 2026, 5:22 PM EDT
Recruiting Not applicable Interventional

Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease

NCT06305624
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol-related Liver Disease
Interventions
Connections App
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
298 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Lansing, Michigan • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Phase 1 Interventional

Family Check-Up for Adolescents and Siblings

NCT00925340
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Family Check Up, Psychoeducation
Behavioral
Lead sponsor
Brown University
Other
Eligibility
12 Years to 18 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 29, 2014 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Not applicable Interventional

Alcohol Use Disorders in Schizophrenia

NCT00280813
View directory record Official record
Conditions
Schizophrenia, Mood Disorders, Alcohol Abuse, Alcohol Dependence
Interventions
Supportive Treatment in Addiction Recovery (STAR)
Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
22 Years to 60 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
4
States / cities
Baltimore, Maryland • Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Oct 18, 2026, 5:22 PM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Impulsivity and Alcohol Response

NCT03736343
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), Subjective Response to Alcohol (SR)
Interventions
Alcohol
Drug
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 30 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Multimodal Neuroimaging of Alcohol Cues, Cortisol Response, and Compulsive Motivation

NCT04412824
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Intravenous blood draw
Drug
Lead sponsor
Auburn University
Other
Eligibility
21 Years to 45 Years
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 22, 2022 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Phase 1 Interventional

Enhancing the Effects of Alcohol Treatment With L-Carnitine

NCT05355311
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
L-carnitine
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years to 25 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 15, 2025 · Synced Oct 18, 2026, 5:22 PM EDT
Terminated Not applicable Interventional Results available

Cognitive Enhancement Through Computerized Training

NCT04244032
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Working Memory Training, Inhibitory Control Training, Bias Modification Training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
25 Years to 64 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Endotoxin on Alcohol Consumption

NCT04527185
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Endotoxin
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Acamprosate to Reduce Symptoms of Alcohol Withdrawal

NCT00106106
View directory record Official record
Conditions
Alcohol-Related Disorders, Alcohol Dependence, Alcoholism, Healthy Volunteer
Interventions
NMR-spectroscopy, Oral acamprosate
Procedure · Drug
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
21 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 12, 2012 · Synced Oct 18, 2026, 5:22 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Imaging Traumatic Stress and Alcohol Use Disorder With [18F]Bavarostat

NCT06371404
View directory record Official record
Conditions
Alcohol Use Disorder, Post Traumatic Stress Disorder
Interventions
Bavarostat
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2031
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 18, 2026, 5:22 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using Counter Attitudinal Advocacy to Change Drinking Behavior

NCT04042909
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Abuse
Interventions
Counter Attitudinal Advocacy, Personalized Normative Feedback
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 26 Years
Enrollment
591 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 18, 2026, 5:22 PM EDT