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Showing 169–192 of 1,088 matching trials from the live ClinicalTrials.gov search.
Conditions
Alcohol Abuse
Interventions
ABCT_Military
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Worcester, Massachusetts
Conditions
Alcohol Use Disorder
Interventions
Drinking Options - Motivate, Shared Decisions, Telemonitor (DO-MoST)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Palo Alto, California • Ann Arbor, Michigan
Completed No phase listed Observational Accepts healthy volunteers

OPRM1 A118G SNP, Alcohol Response, and Striatal Dopamine

NCT00401999
Conditions
Alcoholism
Interventions
Not listed
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 45 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Alcohol Use Disorder, Hiv, Tobacco Use Disorder
Interventions
Varenicline
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Decatur, Georgia
Conditions
Alcohol Abuse, Alcoholism
Interventions
Ondansetron, Placebo, BASICS Plus
Drug · Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 25 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbia, Maryland
Conditions
Alcohol Use Disorder (AUD), Withdrawal From Addictive Substance; Detoxification, Craving
Interventions
Cannabidiol (CBD), Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Alcoholism, Cocaine Addiction, Drug Addiction
Interventions
Real continuous Theta Burst Stimulation, Sham continuous Theta Burst Stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
25 Years to 55 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Familial Alcoholism Vulnerability
Interventions
Mavoglurant (AFQ056), Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 35 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Hartford, Connecticut
Conditions
Alcoholism
Interventions
CP-866,087
Drug
Lead sponsor
Pfizer
Industry
Eligibility
21 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
11
States / cities
Cerritos, California • New Haven, Connecticut • Washington D.C., District of Columbia + 5 more
Conditions
Schizophrenia, Dual Diagnosis, Schizoaffective Disorder, Psychotic Disorder, Substance Abuse, Alcohol Abuse
Interventions
Clozapine versus typical (conventional) and atypical antipsychotic medications
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
19 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2004
U.S. locations
1
States / cities
Jamaica Plain, Massachusetts
Conditions
Alcohol Abuse, Substance Abuse, Post Traumatic Stress Disorder
Interventions
self-guided mHealth app only, self-guided mHealth app + 'real-time' feedback
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Results available

Theta Burst Stimulation for Alcohol Use Disorder

NCT06060496
Conditions
Alcohol Use Disorder
Interventions
Active cTBS, Sham cTBS
Device
Lead sponsor
Gopalkumar Rakesh
Other
Eligibility
21 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Completed Not applicable Interventional Accepts healthy volunteers

Student Athlete Testing Using Random Notification

NCT00451854
Conditions
Drug Abuse, Alcohol Abuse, Substance Abuse
Interventions
Random, no advanced notice drug and alcohol testing
Procedure
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
13 Years to 19 Years
Enrollment
14,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Alcohol Use Disorder
Interventions
Apremilast 60mg, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Substance-Related Disorders
Interventions
Motivational Enhancement Therapy
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Active, not recruiting Early Phase 1 Interventional

Diclofenac as a KMO Inhibitor

NCT06029296
Conditions
Alcohol Use Disorder
Interventions
Diclofenac, Placebo
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
21 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Catonsville, Maryland
Conditions
Opioid Use Disorder, Alcohol Use Disorder
Interventions
Extended Release Naltrexone, Treatment As usual
Drug · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Active, not recruiting Phase 2 Interventional

Pilot rTMS for AUD+mTBI

NCT03995173
Conditions
Alcohol Use Disorder, Mild Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
repetitive transcranial magnetic stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Hines, Illinois
Conditions
Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions
Drink Tracking (MA), Adaptive Tailored (TA), Tailored (TO)
Behavioral
Lead sponsor
Partnership to End Addiction
Other
Eligibility
21 Years to 75 Years
Enrollment
730 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Neural and Mobile Assessment OF Behavior Change Among Problem Drinkers

NCT03457077
Conditions
Alcohol Use Disorder
Interventions
Brief intervention
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 55 Years
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
New York, New York
Conditions
Diet, Physical Activity, Smoking, Alcohol Abuse
Interventions
Telephone Linked Care - Behavior Change Counseling System, Telephone-linked behavioral counseling
Behavioral
Lead sponsor
American Academy of Family Physicians
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Leawood, Kansas
Completed Not applicable Interventional Accepts healthy volunteers Results available

CARES: A Mobile Health Program for Alcohol Risk Reduction

NCT03927482
Conditions
Alcohol Abuse
Interventions
CARES mobile smart phone app, Check Your Drinking
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 29 Years
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Results available

CBT4CBT With Spanish Alcohol Users

NCT03474588
Conditions
Alcohol Use Disorder
Interventions
Standard treatment (ST) PLUS web-based CBT4CBT, Standard Treatment (ST)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
5
States / cities
Bridgeport, Connecticut • New Haven, Connecticut
Recruiting No phase listed Observational Accepts healthy volunteers

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

NCT06552741
Conditions
Substance Use Disorder, Alcohol Use Disorder
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 99 Years
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2047
U.S. locations
1
States / cities
Baltimore, Maryland