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Showing 1–24 of 67 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Alcohol Consumption, Youth Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Cigarette Use Among Urban Youth Via an M-Health Primary Care Preventive Intervention

NCT03855410
View directory record Official record
Conditions
Tobacco Use, Drug Use, Adolescent Behavior, Alcohol Use, Sexual Risk Behavior
Interventions
S4E, Attention-Matched Control Group
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Ann Arbor, Michigan • Ypsilanti, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 25, 2019 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness-Based College: Stage 1

NCT03124446
View directory record Official record
Conditions
Diet Habit, Physical Activity, Sleep, Loneliness, Emotional Regulation, Alcohol Consumption, Youth, Stress, Psychological
Interventions
Mindfulness-Based College, Enhanced Usual Care Control
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 28 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Sep 26, 2026, 9:32 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Journey of Transformation Curriculum for Native American Youth

NCT05731713
View directory record Official record
Conditions
Alcohol Drinking, Tobacco Use, Substance Use, Sexual Behavior
Interventions
Journey of Transformation-Native Youth Health Leadership Program curriculum
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
13 Years to 16 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brief Intervention to Prevent Alcohol Socialization (BIPAS Alcohol)

NCT05520333
View directory record Official record
Conditions
Alcohol Drinking, Adolescent, Drinking Behavior, Drinking, Alcohol, Adolescent Behavior
Interventions
BIPAS Alcohol
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 7, 2025 · Synced Sep 26, 2026, 9:32 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Online Mindfulness-Based College for Young Adults

NCT04733300
View directory record Official record
Conditions
Depressive Symptoms, Loneliness, Sedentary Behavior, Mindfulness, Physical Activity, Diet, Sleep, Emotional Regulation, Alcohol Consumption, Youth, Stress, Psychological
Interventions
Mindfulness-Based College for Young Adults, Health Education for Young Adults
Behavioral · Other
Lead sponsor
Eric Loucks
Other
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Sep 26, 2026, 9:32 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Parent Intervention to Reduce College Student Drinking and Consequences

NCT04247191
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen, Drinking, College
Interventions
P-Chat+, PBI
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 19 Years
Enrollment
2,061 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PLANTS Pilot Trial

NCT05897827
View directory record Official record
Conditions
Alcohol Drinking, Social Acceptance, Depressive Symptoms, Bullying
Interventions
PLANTS, EMAILS
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preventing Alcohol and Other Drug Use and Violence Among Latino Youth

NCT05240313
View directory record Official record
Conditions
Alcohol Drinking, Violence in Adolescence
Interventions
kiR venezolano
Behavioral
Lead sponsor
Boston College
Other
Eligibility
11 Years to 14 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Doral, Florida
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intergenerational Strengths-Based Program for American Indian Girls as They Transition to Adulthood

NCT03900312
View directory record Official record
Conditions
Sexual Activity, Sex, Alcohol Use, Pregnancy, Drug Use
Interventions
Asdzaan Be'eena' Program
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
8 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chinle, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 3, 2020 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Topiramate on Adolescent Alcohol Use: Efficacy and Mechanisms

NCT01641445
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Topiramate, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
14 Years to 24 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Sep 26, 2026, 9:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Native Spirit: Significant Aim 3: Intervention

NCT06785311
View directory record Official record
Conditions
Substance Use, Self Esteem, Youth Drinking, Prevention, Suicide
Interventions
Native Spirit After-School Program
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Scottsdale, Arizona • Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

REAL Parenting Alcohol and Substance Use App

NCT03932097
View directory record Official record
Conditions
Underage Drinking, Alcohol Use, Underage
Interventions
REAL Parenting, Active Control Materials
Behavioral · Other
Lead sponsor
Real Prevention, LLC
Industry
Eligibility
15 Years to 18 Years
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Clifton, New Jersey
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change

NCT04160754
View directory record Official record
Conditions
Alcohol Use, Underage, Alcohol Problem Drinking, Substance Use
Interventions
Mindfulness Based Relapse Prevention, Control (CTL)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 26 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Phase 2 Interventional Results available

Enhancing the Effects of Alcohol Treatment With Lamotrigine

NCT04770493
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Lamotrigine, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
16 Years to 24 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Sep 26, 2026, 9:32 AM EDT
Active, not recruiting Not applicable Interventional

Technology Interventions for Youth Alcohol Use

NCT05988931
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Web Program + App, Web Program + App + Text Messages
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
12 Years to 19 Years
Enrollment
1,406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Substance Use Prevention Intervention Research Study in Pediatric Primary Care

NCT04450966
View directory record Official record
Conditions
Heavy Drinking, Driving Under the Influence, Riding With Driver Under the Influence
Interventions
Computer-facilitated Screening and Brief Intervention
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 17 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Itasca, Illinois • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 26, 2026, 9:32 AM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Citicoline in Youth Alcohol Use Disorder

NCT05870111
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Citicoline (cytidine diphosphate-choline), Placebo oral capsule
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
16 Years to 22 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project MADD - NIH Underage DUI and Ride

NCT03506880
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen
Interventions
MADD Materials, Surgeon General Materials
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
15 Years to 18 Years
Enrollment
2,352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Neuroscience-Informed Treatment Development for Adolescent Alcohol Use

NCT03238300
View directory record Official record
Conditions
Alcohol Drinking, Control
Interventions
N-Acetylcysteine, Placebo Oral Capsule
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
15 Years to 19 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 26, 2026, 9:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining an Intervention to Reduce High School Drinking

NCT07086508
View directory record Official record
Conditions
Underage Drinking, Drinking, Teen, Adolescent Alcohol Use
Interventions
e-CHECKUP TO GO (eCTG), e-Parent Intervention
Behavioral
Lead sponsor
Binghamton University
Other
Eligibility
15 Years to 65 Years
Enrollment
2,532 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Binghamton, New York
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Experimental Test of Facebook Social Drinking Norms on Adolescent Alcohol Use

NCT03159286
View directory record Official record
Conditions
Feedback, Psychological, Underage Alcohol Use, Risk-Taking
Interventions
Abstainer, Abstainer + User, Control
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
15 Years to 20 Years
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 20, 2019 · Synced Sep 26, 2026, 9:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol Feedback, Reflection and Morning Evaluation

NCT05509218
View directory record Official record
Conditions
Youth Drinking, Alcohol Drinking
Interventions
Mobile-delivered personalized feedback
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 29 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 26, 2026, 9:32 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Efficacy of the Expectancy Challenge Alcohol Literacy Curriculum on Reducing College Student Alcohol Use and Harms

NCT05616247
View directory record Official record
Conditions
Alcohol Use, Underage, Harmful; Use, Alcohol
Interventions
ECALC, ECALC Plus Weekly Boosters
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Sep 26, 2026, 9:32 AM EDT
Recruiting Not applicable Interventional

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

NCT06593652
View directory record Official record
Conditions
Alcohol Use, Adolescent, Mild Alcohol Use Disorder, Mild Substance Use Disorder
Interventions
Teen Intervene - Adolescent Only, Teen Intervene with Caregiver Session, Family Check Up
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
12 Years to 17 Years
Enrollment
615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Sep 26, 2026, 9:32 AM EDT