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Showing 1–24 of 87 matching trials from the live ClinicalTrials.gov search.

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Filters: Condition: Alcohol Craving Clear all

Conditions: Alcohol Dependence, Cocaine Dependence
Interventions: Varenicline, Placebo; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 21 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Alcohol Use Disorder
Interventions: Scarcity Narrative, Neutral Narrative; Behavioral
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 21 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Alcohol Abuse, Posttraumatic Stress Disorder
Interventions: Prazosin, Placebo medication; Drug
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Alcohol Use Disorder
Interventions: Dexamethasone Oral, Placebo; Drug
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Alcoholism
Interventions: Baclofen, Cyproheptadine; Drug
Lead sponsor: Brown University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Alcohol Consumption, Heavy Drinker, Alcohol Use Disorder (AUD)
Interventions: Mavoglurant; Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 50 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: New Haven, Connecticut

Conditions: Alcoholism
Interventions: Ghrelin, Saline solution; Drug
Lead sponsor: Brown University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2011
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Alcohol Use Disorder (AUD), Alcohol Consumption, Craving
Interventions: Probenecid Oral Tablet, Placebo Oral Tablet; Drug
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Alcohol Use Disorder
Interventions: Sunobinop, Placebo to match sunobinop; Drug
Lead sponsor: Knoa Pharma LLC; Industry
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Alcohol Dependence, PTSD
Interventions: Propranolol, Placebo; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 100 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Craving, Alcohol Drinking
Interventions: Dynamic Visual Noise (DVN), Static Visual Noise (SVN); Other
Lead sponsor: University of Wyoming; Other
Eligibility: 18 Years to 29 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Laramie, Wyoming

Conditions: Alcoholism
Interventions: Prazosin medication, Placebo medication; Drug
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years and older
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Alcohol Use Disorder
Interventions: Placebo, Lacosamide 100 mg, Lacosamide 200 mg; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 21 Years to 50 Years · Male only
Enrollment: 4 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Alcohol Dependance
Interventions: medial prefrontal cortex, dorsolateral prefrontal cortex, sham; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years to 40 Years
Enrollment: 71 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Alcohol Dependence
Interventions: Naltrexone, Placebo; Drug
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 21 Years to 65 Years
Enrollment: 83 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: AOD Use, Abuse, and Dependence
Interventions: Oxytocin, Placebo; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years to 50 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Emeryville, California

Conditions: Alcohol Dependence, Post-Traumatic Stress Disorder (PTSD)
Interventions: Progesterone, Placebo (for Progesterone); Drug
Lead sponsor: Yale University; Other
Eligibility: 21 Years to 60 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: West Haven, Connecticut

Conditions: Alcohol Abstinence
Interventions: Guanfacine XR 3mgs/daily, Placebo (for guanfacine); Drug
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Alcohol Dependence
Interventions: Prazosin Tablet, Placebo Tablet; Drug
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2019
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Alcohol Use Disorder
Interventions: Lemborexant 10 mg, Naltrexone; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Alcoholism
Interventions: Naltrexone 50 Mg, Placebo; Drug
Lead sponsor: Brown University; Other
Eligibility: 21 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Ends 2005
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Alcohol Use Disorder, Posttraumatic Stress Disorder (PTSD)
Interventions: Prazosin, Naltrexone, Placebo (Prazosin), Placebo (Naltrexone); Drug
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years to 80 Years
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Alcohol Dependence, Alcohol Abuse
Interventions: Naltrexone, Brenda Therapy Sessions, Placebo; Drug · Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Alcohol Use Disorder
Interventions: Episodic Future Thinking, Control Episodic Thinking; Behavioral
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 21 Years to 65 Years
Enrollment: 154 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Roanoke, Virginia