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Showing 1–24 of 88 matching trials from the live ClinicalTrials.gov search.
Conditions
Alcohol Use Disorder
Interventions
Episodic Future Thinking, Control Episodic Thinking
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
21 Years to 65 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Roanoke, Virginia
Conditions
Healthy, Alcohol Drinking
Interventions
SR141716 (Rimonabant)
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 45 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Alcoholism
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
21 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Alcohol Dependence
Interventions
Naltrexone, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 65 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Charleston, South Carolina
Recruiting Not applicable Interventional

Alcohol-ROC-Training

NCT05491551
Conditions
Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker
Interventions
Mindfulness-Based Treatment-Regulation of Craving, Cognitive-Based Therapy-Regulation of Craving
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 26 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Berkeley, California • New Haven, Connecticut
Conditions
Alcohol Abstinence
Interventions
Guanfacine XR 3mgs/daily, Placebo (for guanfacine)
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Stony Brook, New York
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Neuromodulation of Trauma Memories in PTSD & Alcohol Dependence

NCT01055171
Conditions
Alcohol Dependence, PTSD
Interventions
Propranolol, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 100 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Alcohol Use Disorder (AUD), Obesity (BMI Equal to or >30)
Interventions
Placebo, Semaglutide 1.0 mg, Semaglutide 2.0 mg
Other · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 68 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Results available

Effects of Ghrelin on Alcohol Cue Reactivity and Craving

NCT01190085
Conditions
Alcoholism
Interventions
Ghrelin, Saline solution
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Providence, Rhode Island
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Suvorexant for Alcohol Use Disorder (AUD): Neural Mechanisms

NCT06484075
Conditions
Healthy Volunteers, Alcohol Use Disorder (AUD)
Interventions
Siemens 3T PRISMA MR Scanner, PET/CT Scanner, Suvorexant, Placebo
Device · Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 75 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Alcohol Use Disorder
Interventions
Sunobinop, Placebo to match sunobinop
Drug
Lead sponsor
Knoa Pharma LLC
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Columbus, Ohio
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Baclofen for Treating Anxiety and Alcoholism

NCT01751386
Conditions
Alcoholism, Alcohol Dependence, Alcohol Drinking Related Problems, Alcohol Drinking, Anxiety Disorder
Interventions
Baclofen, Placebo
Drug · Other
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Alcohol Use Disorder, Smoking
Interventions
Oxytocin nasal spray, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Alcoholism
Interventions
Baclofen, Cyproheptadine
Drug
Lead sponsor
Brown University
Other
Eligibility
21 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Alcohol Dependence
Interventions
VIVITROL 380 mg, Placebo
Drug
Lead sponsor
Alkermes, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Belmont, Massachusetts
Conditions
Alcohol Use
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Alcohol Dependence, Anxiety
Interventions
Doxazosin, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years to 65 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Providence, Rhode Island
Completed Phase 2 Interventional Accepts healthy volunteers Results available

An Inflammatory Challenge Using Endotoxin

NCT04310423
Conditions
Alcohol Use Disorder, Inflammatory Response, Craving, Depressed Mood
Interventions
Placebo, Endotoxin
Drug · Biological
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Bipolar Disorder, Alcoholism, Alcohol Abuse
Interventions
Aripiprazole, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Alcohol Dependence
Interventions
Prazosin Tablet, Placebo Tablet
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Terminated Not applicable Interventional Accepts healthy volunteers

Brief ROC Training Effects on Alcohol Drinking

NCT03928626
Conditions
Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker, Alcohol Drinking, Alcohol Drinking in College, Drinking Behavior, Drunkenness, Drinking Excessive, Drinking Problem, Drink Too Much, College Drinking
Interventions
Regulation of craving, Control (NO REGULATION)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 25 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Alcoholism
Interventions
Topiramate
Drug
Lead sponsor
Bankole Johnson
Other
Eligibility
21 Years to 45 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
Charlottesville, Virginia • Richmond, Virginia
Conditions
Alcoholism
Interventions
Naltrexone 50 Mg, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
21 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2005
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Cocaine Dependent, Alcohol Dependent
Interventions
Guanfacine, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut