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ClinicalTrials.gov public records Last synced Oct 21, 2026, 2:55 PM EDT

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Showing 1–24 of 1,240 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol Drinking Clear all
Terminated Phase 2 Interventional Results available

Kappa Opioid Receptor Antagonism for the Tx of AUD and Comorbid PTSD

NCT03852628
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Alcohol Abuse
Interventions
2mg Buprenex and 380mg Vivitrol, Placebo (SL pill qd, IM injection q4weeks)
Drug
Lead sponsor
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Other
Eligibility
18 Years to 70 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Tuscaloosa, Alabama • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Engineering an Online STI Prevention Program: RCT

NCT04095065
View directory record Official record
Conditions
Alcohol Consumption, Sexually Transmitted Diseases
Interventions
itMatters, itMatters and itMatters Sexual Violence Prevention, itMatters Well-being and itMatters Sexual Violence Prevention, itMatters Well-being
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 30 Years
Enrollment
3,098 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
4
States / cities
Fresno, California • Greensboro, North Carolina • Fargo, North Dakota + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2025 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Effects of tDCS Paired With Cognitive Training on Brain Networks Associated With Alcohol Use Disorder in Veterans

NCT04574167
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Ultra-brief Intervention for Problem Drinkers

NCT00688584
View directory record Official record
Conditions
Problem Drinking, Alcoholism
Interventions
Pamphlet-based personalized alcohol feedback (PAF), control pamphlet condition
Behavioral
Lead sponsor
Centre for Addiction and Mental Health
Other
Eligibility
19 Years and older
Enrollment
1,767 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
2
States / cities
Stanford, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 9, 2013 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Gabapentin for Abstinence Initiation in Alcohol Dependence

NCT01141049
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Gabapentin, Placebo
Drug · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Healthy Living as You Age

NCT00379093
View directory record Official record
Conditions
Alcohol Related Disorders, Alcohol Drug Interactions
Interventions
Brief advice
Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
55 Years and older
Enrollment
631 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 13, 2009 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Testing the Effectiveness of a Graphic Novel Health Education Curriculum for Patients With Addiction

NCT02378181
View directory record Official record
Conditions
Alcohol Use, Drug Use
Interventions
Health Education Toolkit, Treatment-as-usual
Behavioral
Lead sponsor
Treatment Research Institute
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 1, 2023 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Phase 4 Interventional Results available

Dutasteride for the Reduction of Alcohol Use in Male Drinkers

NCT01262287
View directory record Official record
Conditions
Alcoholism, Alcohol Abuse, Alcohol Dependence
Interventions
Dutasteride, Placebo
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Early Phase 1 Interventional

Dexamethasone to Target Stress and Immune System Mechanisms Underlying Alcohol Craving

NCT05305404
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Dexamethasone Oral, Placebo
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 55 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Investigating the Interactions of AZD0530 With Alcohol in Social Drinkers

NCT02732587
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Saracatinib
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 50 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 14, 2020 · Synced Oct 21, 2026, 2:55 PM EDT
Active, not recruiting Phase 2 Interventional

Semaglutide Therapy for Alcohol Reduction (STAR)

NCT06015893
View directory record Official record
Conditions
Addiction, Alcohol Use Disorder
Interventions
Take Control, Semaglutide
Behavioral · Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 110 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Motivational Interviewing and Neuroimaging With Adolescents

NCT03367858
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Motivational Interviewing (MI), Brief Adolescent Mindfulness (BAM)
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
14 Years to 19 Years
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Oct 21, 2026, 2:55 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers Results available

The Effects of Exenatide, a GLP-1 Agonist, on Alcohol Self-Administration in Heavy Drinkers

NCT03645408
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Exenatide, Sham injection
Drug · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years to 55 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 9, 2022 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Marijuana Use, Strength Training, and Alcohol Consumption (MUSTAC) Study

NCT04791917
View directory record Official record
Conditions
Chronic Pain
Interventions
Eccentric Biceps Flexion, Concentric Biceps Flexion
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 65 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 21, 2026, 2:55 PM EDT
Not listed Phase 4 Interventional

Bridging ED to Outpatient AUD Therapy With Naltrexone

NCT05228418
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Naltrexone Pill
Drug
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 8, 2022 · Synced Oct 21, 2026, 2:55 PM EDT
Terminated Not applicable Interventional

Targeting Non-virally Suppressed Adults With Alcohol Use Disorder in HIV Primary Care

NCT04280068
View directory record Official record
Conditions
Alcohol Dependence, HIV/AIDS
Interventions
Clinician Guide (CG), Clinician Guide plus HealthCall
Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2020 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Early Phase 1 Interventional

Brain Inflammation and Function in Alcoholism

NCT02233868
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
connectivity, neuroinflammation, neurofunction
Other · Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
30 Years to 75 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 21, 2026, 2:55 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Reducing Hazardous Alcohol Use in Social Networks Using Targeted Intervention: 21 Rising

NCT04147520
View directory record Official record
Conditions
Alcohol Drinking, Alcohol; Harmful Use
Interventions
Brief Motivational Interview
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
1,475 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Screening and Management of Unhealthy Alcohol Use in Primary Care

NCT04248023
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Abuse, Alcohol Use Disorder
Interventions
Practice Facilitation
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
13,680 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 25, 2023 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Not applicable Interventional

Therapeutic Alliances in Alcoholism Treatment

NCT01689103
View directory record Official record
Conditions
Alcohol Use Disorders
Interventions
Cognitive-behavioral treatment
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 65 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 21, 2026, 2:55 PM EDT
Completed Not applicable Interventional Results available

Financial Incentives, Randomization With Stepped Treatment Trial

NCT03089320
View directory record Official record
Conditions
Unhealthy Alcohol Use
Interventions
Contingency Management Counseling, Addiction Physician Management, Motivational Enhancement Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
7
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Oct 21, 2026, 2:55 PM EDT
Active, not recruiting Not applicable Interventional

Clinical Course of Alcohol Use Disorder Recovery

NCT05607290
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Cognitive-Behavioral Treatment
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 21, 2026, 2:55 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Integrative Alcohol and Risky Sex Feedback for College Students

NCT05011903
View directory record Official record
Conditions
Alcohol Drinking in College, Sexual Behavior
Interventions
Cross-tailored Dynamic Feedback, Personalized Feedback Intervention, Dynamic Feedback on General Health Behaviors
Behavioral
Lead sponsor
Anne E Ray
Other
Eligibility
18 Years to 20 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Lexington, Kentucky • Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 21, 2026, 2:55 PM EDT
Active, not recruiting Phase 2 Interventional

Pilot rTMS for AUD+mTBI

NCT03995173
View directory record Official record
Conditions
Alcohol Use Disorder, Mild Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
repetitive transcranial magnetic stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 26, 2025 · Synced Oct 21, 2026, 2:55 PM EDT