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ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:43 PM EDT

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Showing 73–96 of 235 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol Effect Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Study to Determine the Effects of Co-Administration of Alcohol on the Absorption of Oxycodone From a Proprietary Controlled-Release Formulation

NCT01677039
View directory record Official record
Conditions
Healthy
Interventions
Test formulation administered with water, Test formulation administered with 20% ethanol, Test formulation administered with 40% ethanol
Drug
Lead sponsor
Pfizer
Industry
Eligibility
21 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 11, 2012 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Combined Alcohol and Nitrous Oxide Intake - 15

NCT00000263
View directory record Official record
Conditions
Opioid-Related Disorders, Substance-Related Disorders
Interventions
30% Nitrous oxide, 0.25 g/Kg ethanol, 0.5 g/KG ethanol, 0 g/Kg ethanol
Drug · Other
Lead sponsor
University of Chicago
Other
Eligibility
Not listed
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1997 – 1998
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Oct 20, 2026, 1:43 PM EDT
Active, not recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Effect of Nutritional Ketosis on Alcohol Metabolism

NCT06065657
View directory record Official record
Conditions
Ketoses, Metabolic, Ketogenic Dieting, Alcohol Intoxication, Magnetic Resonance Imaging, Alcohol Drinking
Interventions
Ketone Supplement, Control Diet, Ketogenic diet, Ethanol
Dietary Supplement · Other · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 50 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional

Evaluating Within-Person and Between-Person Effects Of A Personalized Normative Feedback Intervention On Drinking As They Are Moderated By Self-Determination

NCT03583515
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Alcohol-Specific Personalized Normative Feedback, Social Media Personalized Normative Feedback
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 2 Interventional Results available

The Effects of Zonisamide on Alcohol Dependence

NCT00406692
View directory record Official record
Conditions
Alcoholism
Interventions
Zonisamide
Drug
Lead sponsor
Boston University
Other
Eligibility
21 Years to 64 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2010 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 2 Interventional Results available

The Effect of NK1R Antagonism on Alcohol Craving and PTSD Symptoms in Alcohol Dependent Patients With PTSD

NCT00896038
View directory record Official record
Conditions
Alcoholism, Alcohol Dependence, Posttraumatic Stress Disorder
Interventions
Aprepitant, Placebo
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 50 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 3, 2015 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Glutamatergic Modulation of Disordered Alcohol Use

NCT02539511
View directory record Official record
Conditions
Alcohol Dependence
Interventions
CI-581a, CI-581b, Motivational Enhancement Therapy (MET)
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 69 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2020 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Fish Oil vs. Placebo on Subjective Effects of Alcohol

NCT03010917
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Fish Oil with ethanol and placebo ethanol infusions, Placebo with ethanol and placebo ethanol infusions
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 22, 2022 · Synced Oct 20, 2026, 1:43 PM EDT
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Impulsivity and Alcohol Response

NCT03736343
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), Subjective Response to Alcohol (SR)
Interventions
Alcohol
Drug
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 30 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 6, 2023 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional Results available

Effect of Theta Burst Stimulation on Alcohol Cue Reactivity

NCT04223154
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Use Disorder, Trauma Injury, Alcohol Dependence, Alcohol Abuse
Interventions
Real iTBS to the dlPFC, Sham iTBS to the dlPFC
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 2 Interventional Results available

Effects and Therapeutic Potential of Psilocybin in Alcohol Dependence

NCT01534494
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Psilocybin
Drug
Lead sponsor
University of New Mexico
Other
Eligibility
25 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 26, 2023 · Synced Oct 20, 2026, 1:43 PM EDT
Terminated Phase 2 Interventional Results available

Topiramate's Effects on Heavy Drinking

NCT02074904
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Topiramate, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 21, 2018 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)

NCT04331288
View directory record Official record
Conditions
Potential Treatment for Alcohol Dependence-Alcohol Interaction
Interventions
PT150, Beverage
Drug · Other
Lead sponsor
Pop Test Oncology LLC
Industry
Eligibility
21 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2023 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Behavioral Effects of Drugs: Inpatient (36) (Alcohol, Duloxetine, and Methylphenidate)

NCT03575403
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Alcohol, Placebos, Duloxetine (60 MG), Methylphenidate, Duloxetine (30 MG)
Drug
Lead sponsor
Craig Rush
Other
Eligibility
21 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Zinc Supplementation in Alcoholic Cirrhosis

NCT02072746
View directory record Official record
Conditions
Alcoholic Cirrhosis
Interventions
Zinc, Placebo
Dietary Supplement
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Estradiol Effects on Alcohol Across the Menstrual Cycle

NCT04595682
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Placebo, Alcohol
Drug
Lead sponsor
Mark Fillmore
Other
Eligibility
21 Years to 35 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effect of Alcohol on Tremors

NCT00001925
View directory record Official record
Conditions
Tremor
Interventions
Alcohol
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 20, 2026, 1:43 PM EDT
Withdrawn Phase 2 Interventional

Oxytocin on Approach Bias and Craving

NCT03865615
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Jennifer Mitchell
Other
Eligibility
21 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Not applicable Interventional

Synergistic Effects of Anxiety and Alcohol Use Among Latinos and Its Sociocultural Mechanisms

NCT03807817
View directory record Official record
Conditions
Alcohol Drinking, Racism
Interventions
Alcohol administration, Placebo, No Alcohol
Other
Lead sponsor
University of Houston
Other
Eligibility
21 Years to 65 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 4 Interventional Results available

Effect of Ethanol Intoxication on the Anti-Hypoglycemic Action of Glucagon

NCT02516150
View directory record Official record
Conditions
Type 1 Diabetes Mellitus
Interventions
Ethanol, Glucagon
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 80 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 1 Interventional

Family Check-Up for Adolescents and Siblings

NCT00925340
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Family Check Up, Psychoeducation
Behavioral
Lead sponsor
Brown University
Other
Eligibility
12 Years to 18 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 29, 2014 · Synced Oct 20, 2026, 1:43 PM EDT
Suspended Not applicable Interventional

The Effect of rTMS to the Prefrontal Cortex in Alcohol Use Disorder

NCT03809286
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
active rTMS, Inpatient admission, sham rTMS
Device · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
22 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 20, 2026, 1:43 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

A Study of Pleiotropic Pioglitazone Effects on the Alcoholic Lung (APPEAL Study)

NCT03060772
View directory record Official record
Conditions
Alcoholism
Interventions
Pioglitazone
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Oct 20, 2026, 1:43 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Vaginal Preparation With Chlorhexidine-alcohol vs. Povidine-iodine vs. Saline

NCT03640507
View directory record Official record
Conditions
Cesarean Section; Infection, Surgical Site Infection
Interventions
Chlorhexidine-alcohol, Povidine-iodine, Sterile saline
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 9, 2020 · Synced Oct 20, 2026, 1:43 PM EDT