- Conditions
- Alcoholic Hepatitis
- Interventions
- Sodium Hyaluronate, Placebo
- Drug
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 54 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
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Showing 1–24
of 65
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Alcoholic Hepatitis
- Interventions
- Fecal Microbiota Transplantation, Placebo
- Biological · Other
- Lead sponsor
- Prasun Kumar Jalal
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Liver Diseases, Alcoholic, Alcohol-Related Disorders, Transplant; Failure, Liver, Transplant; Complication, Rejection, Liver Diseases, Hepatitis, Alcoholic, Alcohol-Induced Disorders
- Interventions
- liver transplant
- Procedure
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2029
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Alcohol-associated Hepatitis
- Interventions
- IL-22, Prednisone, Acamprosate, Prednisone placebo, IL-22 (F-652) Placebo, Motivational Interviewing (MI), Motivational Enhancement Therapy (MET), Usual Care
- Drug · Behavioral
- Lead sponsor
- Samer Gawrieh
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 216 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 6
- States / cities
- Indianapolis, Indiana • Louisville, Kentucky • Rochester, Minnesota + 3 more
- Conditions
- Patient Adherence, Chronic Hepatitis C, Alcohol-related Disorders
- Interventions
- VBMI
- Behavioral
- Lead sponsor
- G.V. (Sonny) Montgomery VA Medical Center
- Federal
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Jackson, Mississippi
- Conditions
- Acute Alcoholic Hepatitis
- Interventions
- ELAD treatment, Standard of care (Control)
- Biological · Other
- Lead sponsor
- Vital Therapies, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 203 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 35
- States / cities
- Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 25 more
- Conditions
- Hepatorenal Syndrome
- Interventions
- Terlipressin, Placebo
- Drug
- Lead sponsor
- Mallinckrodt
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 196 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2013
- U.S. locations
- 71
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 51 more
- Conditions
- Alcoholism, Alcohol Abuse, Hepatitis C, Liver Disease
- Interventions
- 3 session brief intervention with health behavior feedback, treatment as usual
- Behavioral · Other
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2006
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Alcoholic Hepatitis
- Interventions
- Standard of care + pegfiltrastim, Standard of care
- Drug
- Lead sponsor
- Timothy Morgan, MD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 34 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 5
- States / cities
- Loma Linda, California • Long Beach, California • Los Angeles, California + 2 more
- Conditions
- Carcinoma, Hepatocellular, Liver Cirrhosis, Alcoholic, Hepatitis, Alcoholic, Hepatitis, Chronic, Hepatitis, Viral, Human
- Interventions
- Not listed
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 1,871 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2009 – 2020
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland
- Conditions
- Alcoholic Hepatitis
- Interventions
- DUR-928 (Moderate AH), DUR-928 (Severe AH)
- Drug
- Lead sponsor
- Craig James McClain
- Other
- Eligibility
- 21 Years to 67 Years
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Louisville, Kentucky
- Conditions
- Type 2 Diabetes Mellitus, Obesity
- Interventions
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Procedure · Behavioral
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 25 Years to 55 Years
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2028
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Alcoholic Hepatitis (AH)
- Interventions
- Selonsertib, Prednisolone, Placebo
- Drug
- Lead sponsor
- Gilead Sciences
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 104 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 11
- States / cities
- Little Rock, Arkansas • Coronado, California • Los Angeles, California + 8 more
- Conditions
- Hepatitis C, Liver Diseases, Drug Abuse, Alcoholism
- Interventions
- Pegylated Interferon and Ribavirin, Psychosocial, On-site (MMT Clinic) HCV evaluation and treatment, Off-site HCV evaluation and treatment
- Drug · Behavioral
- Lead sponsor
- State University of New York - Upstate Medical University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 111 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2007
- U.S. locations
- 2
- States / cities
- Syracuse, New York
- Conditions
- Acute Liver Failure, Acute Liver Injury, Drug Induced, Acute on Chronic Liver Failure (ACLF), Acute Alcoholic Hepatitis
- Interventions
- miroliverELAP treatment
- Combination Product
- Lead sponsor
- Miromatrix Medical Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 8
- States / cities
- Chicago, Illinois • Ann Arbor, Michigan • Minneapolis, Minnesota + 5 more
- Conditions
- Cirrhosis, Cirrhosis, Liver, Cirrhosis Early, Cirrhosis Due to Hepatitis B, Cirrhosis Advanced, Cirrhosis Infectious, Cirrhosis Alcoholic, Cirrhosis Due to Hepatitis C
- Interventions
- Rosuvastatin
- Drug
- Lead sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- NIH
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 256 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2029
- U.S. locations
- 13
- States / cities
- La Jolla, California • Los Angeles, California • San Francisco, California + 7 more
- Conditions
- Acute Alcoholic Hepatitis
- Interventions
- ELAD System, Standard of Care (Control)
- Biological · Other
- Lead sponsor
- Vital Therapies, Inc.
- Industry
- Eligibility
- 18 Years to 49 Years
- Enrollment
- 151 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 21
- States / cities
- Little Rock, Arkansas • Coronado, California • Palo Alto, California + 16 more
- Conditions
- Acute Alcoholic Hepatitis
- Interventions
- Lactobacillus Rhamnosus GG, Placebo for Probiotic
- Dietary Supplement · Drug
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2021
- U.S. locations
- 3
- States / cities
- Louisville, Kentucky • Cleveland, Ohio • Dallas, Texas
- Conditions
- Alcohol Associated Hepatitis
- Interventions
- INT-787, Placebo
- Drug
- Lead sponsor
- Intercept Pharmaceuticals
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 67 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 20
- States / cities
- Fresno, California • Palo Alto, California • Sacramento, California + 17 more
- Conditions
- Alcohol Dependence, Chronic Hepatitis C
- Interventions
- Motivational Enhancement Therapy (MET), Health education
- Behavioral
- Lead sponsor
- US Department of Veterans Affairs
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 139 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 2
- States / cities
- Minneapolis, Minnesota • Portland, Oregon
- Conditions
- Human Immunodeficiency Virus, Hepatitis C, Alcohol Abuse
- Interventions
- Computer-based alcohol reduction intervention, Brief clinician-delivered MET, Standard of care
- Behavioral
- Lead sponsor
- New York University
- Other
- Eligibility
- 21 Years to 45 Years · Female only
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Alcohol Use Disorder, Alcoholic Hepatitis
- Interventions
- Integrated AUD Treatment
- Behavioral
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2027
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Alcoholic Hepatitis
- Interventions
- DUR-928 30 mg, DUR-928 90 mg, Placebo+ Standard of Care (SOC)
- Drug
- Lead sponsor
- Durect
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 307 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 48
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Coronado, California + 33 more
- Conditions
- Alcoholic Hepatitis
- Interventions
- F-652
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota