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Showing 1–24 of 80 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Alcohol Problem Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Substance Use Interventions for Truant Adolescents

NCT03655574
View directory record Official record
Conditions
Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized, Substance Abuse, Alcohol Abuse
Interventions
Motivational + Family Check-up (MET+FCU), Psychoeducation
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
12 Years to 18 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 2, 2024 · Synced Sep 2, 2026, 9:15 PM EDT
Recruiting Not applicable Interventional

Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building

NCT07217795
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), PTSD
Interventions
CBT + expressive writing, Wait-List Control
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Not applicable Interventional

AABM to Decrease Problem Drinking and Impulsivity in Veterans With AUD: A Pilot Study

NCT02600832
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
AABM Training, Sham Training
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Not applicable Interventional

Neural and Behavioral Effects of Cognitive Bias Modification (CBM)

NCT04430543
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Cognitive Bias Modification, Sham Training
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 34 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 9, 2022 · Synced Sep 2, 2026, 9:15 PM EDT
Enrolling by invitation Not applicable Interventional

Personalizing Treatment Delivery

NCT05821634
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
Interventions
Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Behavioral Activation Intervention Administered in a College Freshman Orientation Course

NCT04038190
View directory record Official record
Conditions
Alcohol; Use, Problem, Stress, Binge Eating, Depression
Interventions
behavioral activation
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
17 Years and older
Enrollment
572 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 2, 2026, 9:15 PM EDT
Active, not recruiting Not applicable Interventional

Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA

NCT04955795
View directory record Official record
Conditions
Hiv, Alcohol Problem
Interventions
Alcohol Brief Intervention (BI), Common Elements Treatment Approach (CETA) via Telemedicine
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Phase 4 Interventional

Targeted Naltrexone for Problem Drinkers

NCT00369408
View directory record Official record
Conditions
Alcoholism, Alcohol Drinking, Alcohol Dependence
Interventions
Naltrexone, placebo
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 70 Years
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 19, 2011 · Synced Sep 2, 2026, 9:15 PM EDT
Terminated Not applicable Interventional

Assessing the Fit of Motivational Interviewing by Cultures With Adolescents

NCT01948700
View directory record Official record
Conditions
Alcoholism
Interventions
Motivational Interviewing, Education
Behavioral · Other
Lead sponsor
University of New Mexico
Other
Eligibility
13 Years to 18 Years
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Not applicable Interventional Results available

Alcohol Pharmacotherapy for HIV+ Prisoners

NCT01077310
View directory record Official record
Conditions
Alcohol Dependence, Problem Drinking, Hazardous Drinking, Human Immunodeficiency Virus, AIDS
Interventions
Vivitrol- Intramuscular naltrexone (depot-formulation), Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Sep 2, 2026, 9:15 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

DRT Mobile Intervention to Increase Safe Drinking

NCT05098639
View directory record Official record
Conditions
Alcohol; Use, Problem
Interventions
BASICS, Deviance Regulation Theory (DRT)
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 26 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Not applicable Interventional

Brief New Treatment for Suicide Attempts

NCT03300596
View directory record Official record
Conditions
Suicide, Attempted, Drug Use, Alcohol; Use, Problem
Interventions
Brief intervention to prevent suicide attempt, Enhanced treatment as usual
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Not applicable Interventional Results available

Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individuals

NCT05520190
View directory record Official record
Conditions
Mental Health Issue, Alcohol Use Disorder, Depression, Anxiety, Insomnia, Post Traumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Sep 2, 2026, 9:15 PM EDT
Not yet recruiting Not applicable Interventional

The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veterans

NCT06746727
View directory record Official record
Conditions
Alcohol Problems, Post-Traumatic Stress Disorder
Interventions
Acceptance and Commitment Therapy for Social Health, Achievement, and Relationship Effectiveness (ACT-SHARE)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2030
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Sep 2, 2026, 9:15 PM EDT
Not listed Not applicable Interventional

Messaging Interventions to Reduce Alcohol Problems Project

NCT03695653
View directory record Official record
Conditions
Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions
Drink Tracking (MA), Adaptive Tailored (TA), Tailored (TO)
Behavioral
Lead sponsor
Partnership to End Addiction
Other
Eligibility
21 Years to 75 Years
Enrollment
730 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Not applicable Interventional

Helping College Students With ADHD Lead Healthier Lifestyles

NCT02829970
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Alcohol-Related Disorders, Substance-Related Disorders
Interventions
SUCCEEDS Program, Living a Healthy College Lifestyle
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 24 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Sep 2, 2026, 9:15 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Game-Based Intervention to Reduce Alcohol Use Among Youth

NCT07463118
View directory record Official record
Conditions
Alcohol Problem
Interventions
Food4Thought, Singularities
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years to 18 Years
Enrollment
1,992 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing Brief Personalized Feedback Integrating EMA Alcohol Cue Information

NCT05373706
View directory record Official record
Conditions
Alcohol Drinking, Problem Drinking
Interventions
Alcohol Cue Reactivity Personalized Feedback Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 24 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Phase 3 Interventional

Medication and Counseling for Controlled Drinking (Project SMART)

NCT00444418
View directory record Official record
Conditions
Alcohol-related Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions
Naltrexone, Modified Behavioral Self-Control Psychotherapy, Brief Behavioral Compliance Enhancement Therapy
Drug · Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 65 Years · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School

NCT04478240
View directory record Official record
Conditions
Substance Use, Stress, Relation, Interpersonal, Bullying, Victimisation, Mental Health Issue, Sleep, Inadequate, Social Skills
Interventions
PeerLearning.net
Behavioral
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
Not listed
Enrollment
924 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Sep 2, 2026, 9:15 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Game-Based Intervention to Reduce Alcohol-Related Harms Among Sexual and Gender Minority Youth

NCT06215664
View directory record Official record
Conditions
Alcohol Problem, Harm Reduction, Alcohol-Related Harm
Interventions
Singularities Game, Food4Thought
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years to 18 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 2, 2026, 9:15 PM EDT
Recruiting Phase 1 Interventional

Spironolactone in Alcohol Use Disorder (SAUD)

NCT05807139
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Placebo, Spironolactone
Other · Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
21 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Phase 4 Interventional Results available

Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems

NCT02504931
View directory record Official record
Conditions
PTSD, Alcohol Use Disorder
Interventions
Sertraline, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 9, 2018 · Synced Sep 2, 2026, 9:15 PM EDT
Completed Not applicable Interventional

A Medical Assistant-Based Program to Promote Healthy Behaviors in Primary Care

NCT00273806
View directory record Official record
Conditions
Smoking, Problem Drinking, Sedentary Lifestyle, Unhealthy Diet
Interventions
Intervention for 4 behavioral risks by medical assistants.
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
864 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
6
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2008 · Synced Sep 2, 2026, 9:15 PM EDT