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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Alcohol Problem Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Substance Use Interventions for Truant Adolescents

NCT03655574
View directory record Official record
Conditions
Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized, Substance Abuse, Alcohol Abuse
Interventions
Motivational + Family Check-up (MET+FCU), Psychoeducation
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
12 Years to 18 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 2, 2024 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School

NCT04478240
View directory record Official record
Conditions
Substance Use, Stress, Relation, Interpersonal, Bullying, Victimisation, Mental Health Issue, Sleep, Inadequate, Social Skills
Interventions
PeerLearning.net
Behavioral
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
Not listed
Enrollment
924 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Jun 10, 2026, 4:56 AM EDT
Terminated Not applicable Interventional

Assessing the Fit of Motivational Interviewing by Cultures With Adolescents

NCT01948700
View directory record Official record
Conditions
Alcoholism
Interventions
Motivational Interviewing, Education
Behavioral · Other
Lead sponsor
University of New Mexico
Other
Eligibility
13 Years to 18 Years
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Jun 10, 2026, 4:56 AM EDT
Not yet recruiting Not applicable Interventional

Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms

NCT07485036
View directory record Official record
Conditions
Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
Interventions
Contingency Management & Problem Solving Therapy, Usual Care
Behavioral · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing Brief Personalized Feedback Integrating EMA Alcohol Cue Information

NCT05373706
View directory record Official record
Conditions
Alcohol Drinking, Problem Drinking
Interventions
Alcohol Cue Reactivity Personalized Feedback Intervention
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 24 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional

Ultra-brief Intervention for Problem Drinkers

NCT00688584
View directory record Official record
Conditions
Problem Drinking, Alcoholism
Interventions
Pamphlet-based personalized alcohol feedback (PAF), control pamphlet condition
Behavioral
Lead sponsor
Centre for Addiction and Mental Health
Other
Eligibility
19 Years and older
Enrollment
1,767 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
2
States / cities
Stanford, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 8, 2013 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional

Neural and Behavioral Effects of Cognitive Bias Modification (CBM)

NCT04430543
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Cognitive Bias Modification, Sham Training
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years to 34 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 9, 2022 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neural and Mobile Assessment OF Behavior Change Among Problem Drinkers

NCT03457077
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Brief intervention
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
21 Years to 55 Years
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 4, 2023 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Phase 3 Interventional

Medication and Counseling for Controlled Drinking (Project SMART)

NCT00444418
View directory record Official record
Conditions
Alcohol-related Disorders, Alcohol Drinking, Alcoholism, Alcohol Abuse
Interventions
Naltrexone, Modified Behavioral Self-Control Psychotherapy, Brief Behavioral Compliance Enhancement Therapy
Drug · Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 65 Years · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Jun 10, 2026, 4:56 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

DRT Mobile Intervention to Increase Safe Drinking

NCT05098639
View directory record Official record
Conditions
Alcohol; Use, Problem
Interventions
BASICS, Deviance Regulation Theory (DRT)
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 26 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Jun 10, 2026, 4:56 AM EDT
Recruiting Not applicable Interventional

Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault

NCT06444295
View directory record Official record
Conditions
Posttraumatic Stress Symptom, Alcohol Drinking, Alcohol Problem
Interventions
Activity scheduling, Cognitive restructuring, Coaching calls, Non-core intervention components
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
464 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individuals

NCT05520190
View directory record Official record
Conditions
Mental Health Issue, Alcohol Use Disorder, Depression, Anxiety, Insomnia, Post Traumatic Stress Disorder
Interventions
Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS)
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Jun 10, 2026, 4:56 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Brief ROC Training Effects on Alcohol Drinking

NCT03928626
View directory record Official record
Conditions
Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker, Alcohol Drinking, Alcohol Drinking in College, Drinking Behavior, Drunkenness, Drinking Excessive, Drinking Problem, Drink Too Much, College Drinking
Interventions
Regulation of craving, Control (NO REGULATION)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 25 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional

Alcohol Telemedicine Consultation in Primary Care (ATC)

NCT05252221
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), Pharmacist-Patient Relations, Alcohol Problem
Interventions
ATC Intervention
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
41,843 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Oakland, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional

E-Health Coping Skills Training for Women Whose Partner Has a Drinking Problem

NCT02984241
View directory record Official record
Conditions
Alcohol Abuse
Interventions
eHealth Coping Skills Training, eHealth Usual Web Care, Coach Support
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older · Female only
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional

Project Motion, A Study of Motivational Interviewing to Reduce Heavy or Problematic Drinking

NCT00665249
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Abuse
Interventions
Motivational Interviewing, Spirit-Only Motivational Interviewing, Self-Change
Behavioral · Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 65 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2015 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Phase 3 Interventional

ASAP Study - Hospital-Based Brief Intervention for Alcohol Problems

NCT00183105
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Consumption
Interventions
Brief Intervention (adaptation of motivational interviewing)
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2010 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

ED-Home Pilot Study

NCT03864341
View directory record Official record
Conditions
Housing Problems, Drug Use, Alcohol; Use, Problem
Interventions
Referral to homelessness prevention services, Substance use services, Follow-up
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Developing e-Covery, an App-based Intervention to Support Individuals With Co-occurring Problem Alcohol and Opioid Use

NCT05325788
View directory record Official record
Conditions
Alcohol Use Disorder, Opioid Use Disorder
Interventions
e-Covery, Comparator Condition
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional Results available

Improving Outcomes for Emergency Department Patients With Alcohol Problems

NCT03536546
View directory record Official record
Conditions
Drinking, Alcohol
Interventions
Alcohol Peer Mentor Intervention, Brief Advice
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Phase 4 Interventional

Naltrexone for Early Problem Drinkers

NCT00000455
View directory record Official record
Conditions
Alcoholism
Interventions
naltrexone
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 60 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2002
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 19, 2011 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Manipulating Ghrelin Signaling Via GOAT Inhibition in Alcohol Use Disorder

NCT03896516
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Placebo, GLWL-01
Other · Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Jun 10, 2026, 4:56 AM EDT
Completed Not applicable Interventional

Integrated Treatment of Marijuana Abuse for HIV+ Youth

NCT00683488
View directory record Official record
Conditions
HIV Infections
Interventions
Focus Group, First Intervention Trial, Intervention Trial 2
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 24 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
3
States / cities
Los Angeles, California • New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2017 · Synced Jun 10, 2026, 4:56 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Game-Based Intervention to Reduce Alcohol Use Among Youth

NCT07463118
View directory record Official record
Conditions
Alcohol Problem
Interventions
Food4Thought, Singularities
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years to 18 Years
Enrollment
1,992 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jun 10, 2026, 4:56 AM EDT