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Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Alcohol Use, Unspecified Clear all
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Opioid Modulation and Neural Reward Activation in Healthy Adults

NCT04854551
View directory record Official record
Conditions
Alcohol Drinking, Opioid Use, Unspecified
Interventions
Naltrexone, Placebo
Drug · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 35 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 5, 2026, 5:25 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Partnering to Enhance Emerging Adults' Response to Programs

NCT06115252
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Motivational Interviewing (MI)
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 24 Years
Enrollment
248 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Study of a Smartphone-Based Alcohol Reduction Program

NCT06401967
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Pivot Clear, BACtrack breathalyzer
Behavioral · Device
Lead sponsor
Pivot Health Technologies Inc.
Industry
Eligibility
21 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Carlos, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2024 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Longitudinal Use of Protective Behavioral Strategies

NCT04699955
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Deviance Regulation Theory
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 21 Years
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jan 6, 2021 · Synced Sep 5, 2026, 5:25 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)

NCT06259916
View directory record Official record
Conditions
Cannabis Use, Alcohol Use, Unspecified
Interventions
Alcohol, Cannabis
Other
Lead sponsor
Colorado State University
Other
Eligibility
21 Years to 50 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Narrative Writing to Promote Healthy Decisions About Alcohol During the Transition Out of High School

NCT06191861
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Most hoped for future self, Most feared future self, Control (trip to zoo), Balanced future self
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
17 Years to 19 Years
Enrollment
468 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Alcohol Cessation Among Head and Neck Cancer Survivors

NCT05570851
View directory record Official record
Conditions
Head and Neck Cancer, Alcohol Use, Unspecified
Interventions
Alcohol Cessation Text Messages, Usual Care
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Optimizing a Digital AEP Risk Intervention With Native Women and Communities

NCT06324929
View directory record Official record
Conditions
Alcohol Exposed Pregnancy, Unplanned Pregnancy, Alcohol Use, Unspecified, Contraception Use, Sexual Behavior
Interventions
CARRII Native Rapid Pilot Testing
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
407 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Narrative Writing to Promote Healthy Decisions About Alcohol During the Transition Out of College

NCT07418424
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Most hoped for future self, Most feared future self, Balanced future self, Control (trip to zoo)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 25 Years
Enrollment
468 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Development of Education Materials for Prevention of FAS in Russia

NCT01971398
View directory record Official record
Conditions
Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome (FAS), Alcohol Related Neurodevelopmental Disorder, Alcohol Use Complicating Pregnancy, Unspecified Trimester
Interventions
Positive FASD education brochure, Negative FASD education brochure, Active comparator (a general women's health brochure)
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
422 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 28, 2013 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Results available

Alcohol Biosensor Monitoring for Alcoholic Liver Disease

NCT03533660
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Feedback, Enhanced Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 6, 2022 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Estradiol Effects on Alcohol Across the Menstrual Cycle

NCT04595682
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Placebo, Alcohol
Drug
Lead sponsor
Mark Fillmore
Other
Eligibility
21 Years to 35 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Results available

Technology-Based Intervention for Reducing Sexually Transmitted Infections and Substance Use During Pregnancy

NCT03826342
View directory record Official record
Conditions
Sexually Transmitted Infection, Alcohol Use Complicating the Puerperium, Alcohol Use Complicating Pregnancy, Unspecified Trimester, Drug Use
Interventions
Health Check-up for Expectant Moms, Time, attention, and information-matched control
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Results available

Internet-based Videoconferencing to Address Alcohol Use and Pain

NCT03982433
View directory record Official record
Conditions
Chronic Pain, Alcohol Use, Unspecified
Interventions
Motivation and Cognitive Behavioral Management for Alcohol and Pain
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development of a Mindfulness-Based Treatment for the Reduction of Alcohol Use and Smoking Cessation

NCT03734666
View directory record Official record
Conditions
Tobacco Use, Alcohol Use, Unspecified
Interventions
Mindfulness Based Relapse Prevention - Smoking and Alcohol, Cognitive Behavioral Therapy
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Research Evaluating Sleep & Trends for Universal Prevention

NCT04783519
View directory record Official record
Conditions
Insomnia, Alcohol Use, Unspecified, Marijuana Use
Interventions
Brief Behavioral Therapy for Insomnia (BBTI), Brief Alcohol Screening and Intervention for College Students (BASICS)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 24 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Sep 5, 2026, 5:25 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Whole Selves User Testing and Feasibility Study

NCT06392542
View directory record Official record
Conditions
Alcohol Use, Unspecified, Relationship, Social, Depression, Anxiety
Interventions
Whole Selves
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 30 Years
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Concurrent Hookah and Alcohol Consumption on Smoking Topography and Toxicant Exposure

NCT03096860
View directory record Official record
Conditions
Alcohol Use, Unspecified, Hookah Smoking
Interventions
Active alcohol consumption, Placebo consumption
Other
Lead sponsor
Oklahoma State University
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Remotely Delivered Programs Targeting COVID-19 Stress-Related Depression and Substance Use

NCT04595084
View directory record Official record
Conditions
Depression, Anxiety, Substance Use, Stress, Psychological, Stress, Emotional, Alcohol Use, Unspecified, Drug Use, Covid19
Interventions
Mindfulness Based Cognitive Therapy for Resilience During COVID-19 plus CHAMindWell, Internet Cognitive Behavioral Therapy plus CHAMindWell, CHAMindWell
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years to 70 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Drinking, Acetate, and Stress

NCT06584448
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Use, Unspecified, Heavy Drinker, Alcohol Use Disorder, Moderate, in Sustained Remission
Interventions
Deuterium Metabolic Imaging with deuterated acetate tracer
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Life Enhancing Alcohol-management Program

NCT04302740
View directory record Official record
Conditions
Alcohol Use, Unspecified, Homelessness, Harm Reduction, Community Based Participatory Research
Interventions
LEAP
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
21 Years and older
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 28, 2025 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Motivational Interviewing and Neuroimaging With Adolescents

NCT03367858
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Motivational Interviewing (MI), Brief Adolescent Mindfulness (BAM)
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
14 Years to 19 Years
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Text Message Intervention for Alcohol Use and Sexual Violence in College Students

NCT05065918
View directory record Official record
Conditions
Alcohol Use, Unspecified, Sexual Violence, Sexual Assault
Interventions
sexual violence and alcohol use harm reduction text message content, alcohol use reduction content
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 24 Years
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Personalized Feedback Programs for College Students

NCT04975191
View directory record Official record
Conditions
Alcohol Use, Unspecified
Interventions
Resources, Personalized Feedback Program (PFP), Substance Use Feedback Program (BMI)
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 30, 2023 · Synced Sep 5, 2026, 5:25 PM EDT