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ClinicalTrials.gov public records Last synced Oct 20, 2026, 10:12 PM EDT

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Showing 337–360 of 1,300 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol Use Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating Telehealth Delivery of Brief Alcohol Screening and Intervention for College Students

NCT06774300
View directory record Official record
Conditions
Alcohol Consumption
Interventions
BASICS, Online alcohol programming
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 26 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Not applicable Interventional

Intensive Intervention for Smokers - 6

NCT00217984
View directory record Official record
Conditions
Tobacco Use Disorder, Alcohol Dependence
Interventions
Usual Care, Extended cognitive behavior therapy
Other · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 75 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2017 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Phase 2 Interventional Results available

Effects of Cortical Dopamine Regulation on Drinking, Craving, and Cognitive Control

NCT02949934
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Tolcapone, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 40 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 9, 2023 · Synced Oct 20, 2026, 10:12 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Mechanistic Evaluation of Guanfacine on Drinking Behavior in Women and Men With Alcohol Use Disorders

NCT03764098
View directory record Official record
Conditions
Alcohol Use
Interventions
Guanfacine ER, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
21 Years to 70 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 20, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention

NCT06005298
View directory record Official record
Conditions
Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
Interventions
Screening, Brief Intervention, Referral to Treatment (SBIRT)
Behavioral
Lead sponsor
Shirish S Barve
Other
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Phase 3 Interventional Results available

Treatment Strategy for Alcohol Use Disorders in Veterans With TBI

NCT01342549
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Valproate, Naltrexone
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years · Male only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Iowa City, Iowa • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 9, 2016 · Synced Oct 20, 2026, 10:12 PM EDT
Completed No phase listed Observational

The Efficacy of Computerized Alcohol Screening and Intervention (CASI) in At-Risk Emergency Department and Trauma Patients

NCT01680614
View directory record Official record
Conditions
Alcohol Consumption
Interventions
CASI
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
2,114 participants
Timeline
2013 – 2015
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 20, 2026, 10:12 PM EDT
Recruiting Phase 2 Interventional

Tirzepatide in MetALD

NCT07046819
View directory record Official record
Conditions
Metabolic Alcohol-associated Liver Disease, Alcohol Use Disorder
Interventions
Tirzepatide, Placebo
Drug · Other
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Mifepristone for the Prevention of Relapses of Alcohol Drinking

NCT02243709
View directory record Official record
Conditions
Alcohol Use Disorders (AUD)
Interventions
Mifepristone 600-mg/day or placebo for a week
Drug
Lead sponsor
Brown University
Other
Eligibility
21 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 10, 2025 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Phase 2 Interventional Results available

Harm Reduction With Pharmacotherapy (HaRP)

NCT01932801
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
XR-NTX, Placebo, HRC
Drug · Other · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 65 Years
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 20, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional

The GLUCID Study: Effect of Alcohol Reduction and Probiotic Interventions on Cognition and Brain Glucose Metabolism in Normal Aging Adults Who Are High-Risk Alcohol Drinkers

NCT07415707
View directory record Official record
Conditions
Aging, Alcohol Drinking
Interventions
Visbiome, Motivational Interviewing, Placebo
Dietary Supplement · Behavioral · Other
Lead sponsor
University of Miami
Other
Eligibility
65 Years to 84 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Phase 1Phase 2 Interventional

Developing Violence Prevention Therapy for Substance Abusers

NCT00551863
View directory record Official record
Conditions
Substance Use Disorders, Violence
Interventions
IVPT
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 7, 2015 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing an Online Insomnia Intervention

NCT04564807
View directory record Official record
Conditions
Alcohol Use Disorder, Insomnia
Interventions
Web-Based Insomnia Education Program, SHUTi Intervention
Behavioral
Lead sponsor
Jessica Weafer
Other
Eligibility
21 Years to 50 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alcohol and Cannabis Concentrates Co-Administration

NCT05999344
View directory record Official record
Conditions
Alcohol Use Disorder, Cannabis Use
Interventions
commercially available cannabis administered prior to commercially available alcohol, commercially available alcohol administered prior to commercially available cannabis
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 65 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Oct 20, 2026, 10:12 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Sex Differences in the Response to Abstinence From Alcohol.

NCT03827460
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Abstinence from alcohol, Usual drinking, Intravenous Alcohol
Behavioral · Drug
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 35 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Alcohol Exposed Pregnancy Risk: EARLY Randomized Controlled Trial

NCT01446653
View directory record Official record
Conditions
Alcohol Exposed Pregnancy
Interventions
Motivational Interviewing plus feedback, Video, Informational Brochure
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
232 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
2
States / cities
Charlottesville, Virginia • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 26, 2016 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Teen Connection Project for Trans and Gender Minority Youth

NCT06587139
View directory record Official record
Conditions
Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms, Anxiety, Suicidal Ideation, Risk-Taking, Alcohol Drinking
Interventions
Teen Connection Project (TCP)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Varenicline Augmentation of Patch Outcomes in Heavy Drinkers' Smoking Cessation

NCT02859142
View directory record Official record
Conditions
Smoking Cessation, Alcohol Drinking
Interventions
Chantix, Behavioral Counseling Sessions, NicodermCQ, Placebo
Drug · Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 85 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Oct 20, 2026, 10:12 PM EDT
Completed No phase listed Observational

Comprehensive Process Model of AA-related Behavior Change

NCT04618653
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
assessment only
Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Safer Sex Social Network Intervention

NCT00107562
View directory record Official record
Conditions
Sexual Behavior, Alcohol Drinking, Marijuana Smoking
Interventions
Adolescent Safer Sex Social Network Intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 19 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
2
States / cities
Tampa, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Oct 20, 2026, 10:12 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Alcoholic Liver Disease and the Gut Microbiome

NCT05007470
View directory record Official record
Conditions
Alcohol Use Disorder, Alcoholic Liver Disease, Microbiome
Interventions
VSL #3 112.5 Capsule, Placebo
Drug · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Oct 20, 2026, 10:12 PM EDT
Completed Phase 2 Interventional

Medical Office Intervention for Adolescent Drug Use

NCT00229983
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Motivational Enhancement Therapy
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2016 · Synced Oct 20, 2026, 10:12 PM EDT
Recruiting Not applicable Interventional

Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use Disorder

NCT06399653
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Cervical transcutaneous vagus nerve stimulation (active comparator), Cervical transcutaneous vagus nerve stimulation (sham comparator)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Oct 20, 2026, 10:12 PM EDT
Completed No phase listed Observational Results available

STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse

NCT00369746
View directory record Official record
Conditions
Major Depressive Disorder, Alcohol Use Disorder
Interventions
citalopram
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
674 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 9, 2014 · Synced Oct 20, 2026, 10:12 PM EDT