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Showing 121–144 of 1,300 matching trials from the live ClinicalTrials.gov search.
Conditions
Pancreatitis, Acute, Alcohol Drinking, Health Behavior
Interventions
Not listed
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
5
States / cities
Los Angeles, California • Columbus, Ohio • Pittsburgh, Pennsylvania
Conditions
Alcohol Use Disorder, Alcoholism
Interventions
XR-NTX 380 mg, intramuscular injection, Medical Management, Placebo intramuscular injection
Drug · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Alcohol; Use, Problem, Posttraumatic Stress Disorder
Interventions
Imaginal Exposure, Alcohol Skills Training, Supportive Telehealth
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Alcohol Drinking, Tobacco Use, Drug Use
Interventions
Native PATHS
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
10 Years to 14 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Kingston, Rhode Island
Enrolling by invitation Not applicable Interventional

CPNF Intervention Development and Testing

NCT07036198
Conditions
Alcohol Use
Interventions
Customizable personalized normative feedback (CPNF), Personalized normative feedback (PNF), Attention-Matched Control (AMC)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 24 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Alcohol Use Disorder
Interventions
Drinking Options - Motivate, Shared Decisions, Telemonitor (DO-MoST)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Palo Alto, California • Ann Arbor, Michigan
Terminated Phase 2 Interventional Results available

Topiramate's Effects on Heavy Drinking

NCT02074904
Conditions
Alcohol Drinking
Interventions
Topiramate, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Phase 2 Interventional Results available

Varenicline Treatment of Alcohol Dependence in Smokers

NCT01553136
Conditions
Alcoholism, Alcohol Abuse, Smoking, Alcohol Drinking
Interventions
Varenicline
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
New Haven, Connecticut • New York, New York
Completed Phase 4 Interventional Results available

High Dose Vitamin B1 to Reduce Abusive Alcohol Use

NCT00680121
Conditions
Alcoholism
Interventions
Benfotiamine, Placebo
Drug
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Sexual Activity, Sex, Alcohol Use, Pregnancy, Drug Use
Interventions
Asdzaan Be'eena' Program
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
8 Years and older · Female only
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chinle, Arizona
Conditions
Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Partial Fetal Alcohol Syndrome, Alcohol-related Neurodevelopmental Disorder, Prenatal Alcohol Exposure
Interventions
Choline, placebo supplementation consisting of vegetable glycerin (50% by volume) and deionized water
Dietary Supplement
Lead sponsor
San Diego State University
Other
Eligibility
5 Years to 10 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Diego, California
Completed Not applicable Interventional Results available

Internet-based Videoconferencing to Address Alcohol Use and Pain

NCT03982433
Conditions
Chronic Pain, Alcohol Use, Unspecified
Interventions
Motivation and Cognitive Behavioral Management for Alcohol and Pain
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Alcohol Use Disorder
Interventions
Semaglutide, Placebo
Drug
Lead sponsor
Oklahoma State University Center for Health Sciences
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tulsa, Oklahoma
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

An Augmented Reality Videogame for Alcohol Use Prevention and Harm Reduction in Teens

NCT04351958
Conditions
Alcohol Prevention, Harm Reduction
Interventions
Experimental: Augmented Reality ("No Time Wasted")
Behavioral
Lead sponsor
Yale University
Other
Eligibility
16 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Recruiting Not applicable Interventional Accepts healthy volunteers

Drinking, Acetate, and Stress

NCT06584448
Conditions
Alcohol Use Disorder, Alcohol Use, Unspecified, Heavy Drinker, Alcohol Use Disorder, Moderate, in Sustained Remission
Interventions
Deuterium Metabolic Imaging with deuterated acetate tracer
Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
2
States / cities
New Haven, Connecticut
Conditions
Opioid Use Disorder, Alcohol Use Disorder
Interventions
Extended Release Naltrexone, Treatment As usual
Drug · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Cannabis Impairment Detection Application (CIDA)

NCT04230460
Conditions
Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
Interventions
Cannabis (THC) (Inhaled) Placebo, Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
Drug
Lead sponsor
Advanced Brain Monitoring, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Not yet recruiting Phase 2 Interventional Accepts healthy volunteers

Methylphenidate and Response to Alcohol Cues

NCT07306078
Conditions
Alcohol Use Disorder
Interventions
Methylphenidate Pill, Placebo Pill
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 25 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Alcohol Use Disorder (AUD), Obesity (BMI Equal to or >30)
Interventions
Placebo, Semaglutide 1.0 mg, Semaglutide 2.0 mg
Other · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 68 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness-Based Relapse Prevention for Opioid and Alcohol Use Disorders

NCT04278352
Conditions
Opioid-use Disorder, Opioid Abuse, in Remission, Alcohol Use Disorder, Alcohol Use Disorder, in Remission
Interventions
Mindfulness Based Relapse Prevention
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
3
States / cities
Clemson, South Carolina • Greenville, South Carolina
Conditions
Alcohol Use
Interventions
Step 1: Minimal Intervention, Step 2: Brief Motivational Intervention, Alcohol Assessment
Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years and older
Enrollment
598 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Bristol, Rhode Island
Conditions
Alcohol Use Disorder
Interventions
Intravenous Ethanol, 18F-PF-06445974
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
21 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Teen Connection Project for Trans and Gender Minority Youth

NCT06587139
Conditions
Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms, Anxiety, Suicidal Ideation, Risk-Taking, Alcohol Drinking
Interventions
Teen Connection Project (TCP)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lincoln, Nebraska
Conditions
Alcohol Use Disorder
Interventions
Brief Family-Involved Treatment (B-FIT), Cognitive Behavioral Therapy for Alcohol Use Disorder (CBT for AUD)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Charleston, South Carolina