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ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:16 AM EDT

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Showing 169–192 of 1,300 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol Use Clear all
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Phase 1b Study of DCR-AUD in Healthy Volunteers

NCT05845398
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
DCR-AUD, Placebo
Drug
Lead sponsor
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Industry
Eligibility
21 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Glendale, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 20, 2026, 1:16 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Multimodal Immune and Neuroendocrine Assessment in Drinkers

NCT07220148
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Alcohol Cue Reactivity and Laboratory Alcohol Administration Paradigm
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
21 Years to 25 Years
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 23, 2025 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Phase 3 Interventional

Telephone and Mail Intervention for Alcohol Use Disorders

NCT00204854
View directory record Official record
Conditions
Alcohol Use Disorders
Interventions
telephone counseling
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 59 Years
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 5, 2015 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Not applicable Interventional

Mobile Alcohol Use Intervention

NCT07126613
View directory record Official record
Conditions
Alcohol Misuse
Interventions
Mobile Health Intervention to Reduce Alcohol Use Among Young Adults
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 25 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 20, 2026, 1:16 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Impact of Heavy Alcohol Use on Saliva and Oral Health

NCT06684483
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Dependence
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 100 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation for the Treatment of Veterans With Alcohol Use Disorders

NCT03191266
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Active rTMS, Sham rTMS
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 20, 2026, 1:16 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Norms Re-education to Promote Engagement in Parent-based Interventions

NCT06871982
View directory record Official record
Conditions
Underage Drinking
Interventions
PNF+ PBI, SNMC+ PBI, PH+ PBI
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
17 Years to 20 Years
Enrollment
2,040 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 20, 2026, 1:16 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Neural Correlates During Alcohol Intoxication

NCT06118580
View directory record Official record
Conditions
Alcohol Use Disorder, Intermittent Explosive Disorder
Interventions
Alcohol (Ethanol), Placebo
Drug
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 55 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Phase 2 Interventional

Study of Sunobinop on Craving in Alcohol Use Disorder

NCT06545929
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Sunobinop, Placebo to match sunobinop
Drug
Lead sponsor
Knoa Pharma LLC
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Not applicable Interventional

Transcranial Magnetic Stimulation (TMS) Treatment for Alcohol Use Disorder

NCT03969251
View directory record Official record
Conditions
Alcoholism
Interventions
Transcranial Magnetic Stimulation (rTMS), Sham (SS)
Device
Lead sponsor
Nassima Ait-Daoud Tiouririne
Other
Eligibility
22 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Parent Feedback Intervention Targeting Student Transitions and Alcohol Related Trajectories (+) Efficacy Study

NCT04549454
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Problem Drinking, Parenting
Interventions
FITSTART+ PBI, General Parenting Advice
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
17 Years to 20 Years
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2023 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Not applicable Interventional Results available

Compensatory Cognitive Training Via Telehealth for Veterans With Alcohol Use Disorders

NCT06134128
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Motivationally Enhanced Compensatory Cognitive Training for Addictions Group
Behavioral
Lead sponsor
Portland VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Records for Alcohol Care Enhancement

NCT05492942
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Best Practice Advisory (BPA) and Population Health Management (PHM), Best Practice Advisory (BPA) and Clinical Care Management (CCM), Best Practice Advisory (BPA) and Population Health Management (PHM) and Clinical Care Management (CCM)
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 20, 2026, 1:16 AM EDT
Active, not recruiting Phase 1 Interventional

Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS)

NCT07223983
View directory record Official record
Conditions
Alcohol Use Disorder, Weight Loss, Bariatric Surgery Patients
Interventions
Semaglutide 1.0 mg
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Baclofen for Treating Anxiety and Alcoholism

NCT01751386
View directory record Official record
Conditions
Alcoholism, Alcohol Dependence, Alcohol Drinking Related Problems, Alcohol Drinking, Anxiety Disorder
Interventions
Baclofen, Placebo
Drug · Other
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Mindfulness for Alcohol Use and PTSD Among Veterans

NCT04769986
View directory record Official record
Conditions
Alcohol Use Disorder, Posttraumatic Stress Disorder
Interventions
Mobile Mindfulness-Relapse Prevention (mMBRP), Exercise/healthy eating mobile app
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
3
States / cities
Los Angeles, California • Menlo Park, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Not applicable Interventional

Present- Versus Past-focused Therapy for PTSD and Substance Use Disorder

NCT01274741
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Substance Use Disorder, Alcohol Use Disorder
Interventions
Creating Change (CC), Seeking Safety (SS)
Behavioral
Lead sponsor
VA Boston Healthcare System
Federal
Eligibility
18 Years to 65 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2019 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Phase 2 Interventional Results available

N-acetylcysteine Treatment of Alcohol Use Disorder In Veterans With TBI

NCT02791945
View directory record Official record
Conditions
Traumatic Brain Injury (TBI), Hazardous and Harmful Alcohol Use
Interventions
Medical Management Counseling, N-acetylcysteine, Placebo
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Oct 20, 2026, 1:16 AM EDT
Recruiting Phase 2Phase 3 Interventional

MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

NCT07118839
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Alcohol Use Disorder
Interventions
Full Dose MDMA, MDMA-Assisted psychotherapy, Active Placebo Dose MDMA
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
West Haven, Connecticut • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling

NCT02654236
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Placebo, 10 mg Obeticholic Acid (OCA)
Drug
Lead sponsor
Suthat Liangpunsakul
Other
Eligibility
21 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Not applicable Interventional Results available

Evaluation of PRYSHM for LGBTQIA2S+ Youth

NCT05521906
View directory record Official record
Conditions
Dating Violence, Alcohol Drinking
Interventions
Promoting Resilient Youth with Strong Hearts and Minds (PRYSHM)
Behavioral
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
15 Years to 18 Years
Enrollment
314 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 18, 2025 · Synced Oct 20, 2026, 1:16 AM EDT
Active, not recruiting Phase 2 Interventional

Semaglutide Therapy for Alcohol Reduction (STAR)

NCT06015893
View directory record Official record
Conditions
Addiction, Alcohol Use Disorder
Interventions
Take Control, Semaglutide
Behavioral · Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 110 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 20, 2026, 1:16 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Effects of Alcohol After Bariatric Surgery

NCT01843257
View directory record Official record
Conditions
Obesity
Interventions
Alcohol challenge test Alcohol visit first, Alcohol challenge test Placebo visit first
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 27, 2021 · Synced Oct 20, 2026, 1:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nexus of Risk: Sexual Assault, Alcohol Use, and Risky Sex Among College Women

NCT05892692
View directory record Official record
Conditions
Sexual Assault, Substance Use, Risky Health Behavior, Ema
Interventions
Ecological Momentary Intervention
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 24 Years · Female only
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Oct 20, 2026, 1:16 AM EDT