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Showing 1–24 of 897 matching trials from the live ClinicalTrials.gov search.
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Conditions
Alcohol-related Liver Disease
Interventions
Acomprosate
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Alcohol Use Disorder (AUD), Alcohol-Related Disorders
Interventions
Diclofenac 100mg, Diclofenac 75mg, Diclofenac 50mg, Placebo control
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
21 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Catonsville, Maryland
Conditions
Alcoholism
Interventions
naltrexone (Revia)
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2002
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Alcohol Use Disorder
Interventions
Atomoxetine, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
14 Years to 20 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Major Depressive Disorder, Alcohol Use Disorder
Interventions
citalopram
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
674 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
New York, New York
Conditions
Post Traumatic Concerns, Post Traumatic Stress Disorder, Depression and Suicide Ideation, Alcohol and Drug Use
Interventions
Stepped Care Management
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
14 Years and older
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder

NCT02929979
Conditions
Alcohol Use Disorder, PTSD, Cognitive Dysfunction
Interventions
Cognitive Training, Cognitive training placebo control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Psychotic Disorders, Substance Use
Interventions
Peer Approach to Substances in Early Psychosis Programs, Usual Care Peer Services
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
15 Years to 32 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
15
States / cities
Austin, Texas • Beaumont, Texas • Big Spring, Texas + 12 more
Conditions
Alcoholism, Stress Disorders, Post-Traumatic
Interventions
Experiential acceptance, Cognitive restructuring, No-intervention control: Nutrition information
Behavioral · Other
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Results available

CBT4CBT With Spanish Alcohol Users

NCT03474588
Conditions
Alcohol Use Disorder
Interventions
Standard treatment (ST) PLUS web-based CBT4CBT, Standard Treatment (ST)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
5
States / cities
Bridgeport, Connecticut • New Haven, Connecticut
Conditions
Opioid-use Disorder, Cocaine Use Disorder, Alcohol Use Disorder
Interventions
NavSTAR
Behavioral
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Liver Disease; Alcohol-Related, Cirrhosis, Alcohol Use Disorder
Interventions
Intestinal Microbiota Transplant (IMT) Capsules, Placebo Capsules
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Richmond, Virginia
Completed Phase 2 Interventional Accepts healthy volunteers Results available

An Inflammatory Challenge Using Endotoxin

NCT04310423
Conditions
Alcohol Use Disorder, Inflammatory Response, Craving, Depressed Mood
Interventions
Placebo, Endotoxin
Drug · Biological
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Results available

Automated Reinforcement Management System (ARMS)

NCT04656925
Conditions
Alcohol Use Disorder
Interventions
Contingency management
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Spokane, Washington
Conditions
Alcohol Use Disorder
Interventions
Guanfacine Extended Release (XR), Placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Indianapolis, Indiana • Newark, New Jersey
Withdrawn Not applicable Interventional Accepts healthy volunteers

Ambulatory Alcohol Detoxification With Remote Monitoring

NCT03582150
Conditions
Alcohol Use Disorder
Interventions
Remote Monitoring with Ambulatory Detox
Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Stanford, California
Completed Phase 1Phase 2 Interventional Results available

Human Laboratory Study of Varenicline for Alcohol Use Disorder

NCT03035708
Conditions
Alcohol Use Disorder
Interventions
Varenicline, Placebo oral capsule
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
New Haven, Connecticut • Providence, Rhode Island
Conditions
Alcohol Use Disorder
Interventions
Virtual Reality
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 60 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Conditions
Alcohol Drinking, Drug Abuse, HIV
Interventions
Motivational Network Interview
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Los Angeles, California • Santa Monica, California
Completed Not applicable Interventional Accepts healthy volunteers

Trial of an Adapted STD Screening and Risk Reduction Intervention

NCT02513225
Conditions
Alcohol Use, Drug Use, Diagnostic Self Evaluation, Gonorrhea, Unprotected Sex, Chlamydia, Trichomonas
Interventions
Project EMPWR, Optimized Standard Care (OSC)
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 49 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Fort Apache, Arizona
Conditions
Drinking, Alcohol
Interventions
Wisepill+SMS, Wisepill-only
Behavioral · Other
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Ketogenic Diet on Alcohol Intoxication

NCT07602270
Conditions
Ketogenic Diet, Alcohol Drinking, Alcohol Use Disorder, Magnetic Resonance Imaging, Alcohol Intoxication
Interventions
Ketogenic diet
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Alcohol Dependence
Interventions
Valproate, Naltrexone
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years · Male only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Iowa City, Iowa • Houston, Texas
Conditions
Schizophrenia, Alcoholism, Dual Diagnosis
Interventions
Risperidone + Desipramine
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
4
States / cities
Worcester, Massachusetts • Grand Rapids, Michigan • Lebanon, New Hampshire + 1 more