- Conditions
- Alcohol Use Disorder (AUD)
- Interventions
- Doxazosin, Placebo
- Drug
- Lead sponsor
- Brown University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 184 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2026
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Alcohol Use Disorder (AUD)
- Interventions
- Suvorexant 20 mg, Placebo oral tablet
- Drug
- Lead sponsor
- The Scripps Research Institute
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Substance Use Disorders, Attention Deficit Hyperactivity Disorder
- Interventions
- Atomoxetine
- Drug
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 13 Years to 18 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2007
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Alcohol Use Disorder Cognitive Decline
- Interventions
- Cognitive Remediation Training
- Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 59 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
- Conditions
- Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD)
- Interventions
- Placebo, Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 40µg, Dexmedetomidine (DEX) for sublingual (SL) administration (BXCL501) - 80µg, Ethanol Infusion, PTSD Reactivity Condition, Alcohol Cue Reactivity
- Drug · Procedure · Behavioral
- Lead sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
- Conditions
- Alcohol, Drinking, Alcohol Use Disorder (AUD)
- Interventions
- Michigan SPARC Quality Improvement Intervention
- Behavioral
- Lead sponsor
- Kaiser Permanente
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 9,590 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Alcohol Use Disorder
- Interventions
- Telephone Engagement, Portal Engagement, MI-CBT
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 362 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Alcohol Use Disorder
- Interventions
- Transcranial Magnetic Stimulation (TMS)
- Device
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Alcohol Use Disorder (AUD)
- Interventions
- TMP-301, Placebo
- Drug
- Lead sponsor
- Tempero Bio, Inc.
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 14
- States / cities
- Scottsdale, Arizona • New Haven, Connecticut • Hollywood, Florida + 11 more
- Conditions
- Alcohol-related Liver Disease, Liver Diseases
- Interventions
- ENGAGE-ALD Application (APP), Treatment Facilitation bundle, Enhanced Usual Care
- Behavioral
- Lead sponsor
- Henry Ford Health System
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 268 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Detroit, Michigan
- Conditions
- Alcohol Use Disorder (AUD), Post Traumatic Stress Disorder (PTSD), Insomnia
- Interventions
- Suvorexant, Placebo
- Drug · Other
- Lead sponsor
- Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 76 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 2
- States / cities
- Los Angeles, California • Houston, Texas
- Conditions
- Alcohol Use Disorder (AUD)
- Interventions
- TMS
- Device
- Lead sponsor
- Nicholas Balderston, PhD
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Wernersville, Pennsylvania
- Conditions
- Posttraumatic Stress Disorder, Alcohol Use Disorders
- Interventions
- doxazosin, placebo
- Drug
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- Not listed
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Alcohol Use Disorder
- Interventions
- Donepezil + Cognitive remediation therapy (CRT), Donepezil + Placebo CRT, Placebo medication + Cognitive remediation therapy (CRT), Placebo medication + Placebo CRT
- Combination Product
- Lead sponsor
- VA Connecticut Healthcare System
- Federal
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- West Haven, Connecticut
- Conditions
- Alcohol Use Disorder
- Interventions
- Model 1, Model 2
- Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- PTSD, Alcohol Use Disorder
- Interventions
- 40 IU Intranasal Oxytocin, Placebo, Concurrent Treatment of PTSD and Substance Use Disorders using Prolonged Exposure
- Drug · Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 175 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Alcohol Use Disorder, Opioid Use Disorder
- Interventions
- TMS Low-Dose, TMS High-Dose
- Device
- Lead sponsor
- Washington State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2027
- U.S. locations
- 1
- States / cities
- Portland, Oregon
- Conditions
- Alcohol Use Disorder
- Interventions
- Placebo, Lacosamide 100 mg, Lacosamide 200 mg
- Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 21 Years to 50 Years · Male only
- Enrollment
- 4 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Alcohol Use Disorder
- Interventions
- Semaglutide 3 MG [Rybelsus], Semaglutide 7 MG [Rybelsus], Placebo
- Drug
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Cardiovascular Disease, Alcohol Use Disorder, HIV Risk, Substance Use Disorders
- Interventions
- Navigation, compensation, and personalization
- Behavioral
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 35 Years to 64 Years
- Enrollment
- 87 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Alcohol Use Disorder
- Interventions
- Not listed
- Lead sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- NIH
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 475 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Alcohol Use Disorder (AUD), Transcranial Magnetic Stimulation
- Interventions
- Deep Transcranial Magnetic Stimulation (dTMS) H7 coil
- Device
- Lead sponsor
- VA Palo Alto Health Care System
- Federal
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Major Depressive Disorder, Alcohol Use Disorder
- Interventions
- Mirtazapine, Placebo
- Drug
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Alcohol Use Disorder
- Interventions
- Psilocybin, Inactive Placebo, Supportive therapy sessions
- Drug · Other · Behavioral
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 2
- States / cities
- New Canaan, Connecticut • New York, New York