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ClinicalTrials.gov public records Last synced Jul 24, 2026, 1:07 AM EDT

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Showing 1–24 of 961 matching trials from the live ClinicalTrials.gov search.
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Conditions
Tobacco Use Disorder, Alcohol Use Disorder, Drug Use Disorder, Smoking, Alcohol Drinking, Drug Abuse
Interventions
Family-Skills Training
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
Not listed
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
HIV Infections, Substance Abuse
Interventions
Decision aid, Standard care
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Recruiting Phase 2 Interventional Accepts healthy volunteers

Gii'Igoshimong: Sitting With Your First Family

NCT07075081
Conditions
Substance Use, Mental Health Issue
Interventions
Ceremony
Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Duluth, Minnesota
Conditions
Substance Use Disorders
Interventions
Core Training: FBS System Mapping and MTFS-I Installation, Core Training & Facilitation: FBS System Mapping and MTFS-I Installation plus monthly on-site meetings
Behavioral
Lead sponsor
The National Center on Addiction and Substance Abuse at Columbia University
Other
Eligibility
12 Years to 21 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Brentwood, New York • Buffalo, New York
Conditions
Substance-Related Disorders
Interventions
Navigating my Journey program, Attention Control
Behavioral
Lead sponsor
Inflexxion, Inc.
Industry
Eligibility
13 Years to 21 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Newton, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Intervention for Managing Physical Reactions to Overwhelming Emotions

NCT06299657
Conditions
Anxiety, Substance Use Disorders
Interventions
IMPROVE, PHET
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Pregnancy Related, Substance Use, Mental Health Issue
Interventions
NEXUS intervention, Standardized Non-Medical fetal ultrasound
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 45 Years
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using Aromatherapy in Substance Use Disorder

NCT05660434
Conditions
Substance Use Disorders
Interventions
Aroma Inhaler with Bergamot essential oil
Other
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Morgantown, West Virginia
Completed Not applicable Interventional Results available

E-health Implementation (Iowa)

NCT03954184
Conditions
Substance Use Disorders
Interventions
NIATx-TI with Product Training/On-line Support
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
23,659 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
49
States / cities
Adel, Iowa • Algona, Iowa • Ames, Iowa + 44 more
Conditions
Substance Use
Interventions
ATTC strategy, ISF strategy
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
39
States / cities
Phoenix, Arizona • Claremont, California • Irvine, California + 32 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing an Arts-based Program to Reduce Nurse Stigma Towards Perinatal Substance Use

NCT06410287
Conditions
Nurse's Role, Stigma, Social, Implicit Bias
Interventions
ArtSpective
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
2
States / cities
Saint Cloud, Minnesota • Toledo, Ohio
Conditions
Substance Abuse, Substance Dependence
Interventions
Behavioral Intervention
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
16 Years to 44 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Glen Oaks, New York • Manhasset, New York
Completed Not applicable Interventional Accepts healthy volunteers

Youth to Text or Telehealth for Engagement in HIV Care

NCT03681145
Conditions
HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Depression, Substance Use
Interventions
Counselor delivered telehealth intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 29 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Francisco, California
Conditions
Hiv, Substance Use Disorders
Interventions
Project iSTRIVE, incentivized Directly Observed Therapy (iDOT)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Substance Use Disorders, Opioid-use Disorder, Chronic Pain
Interventions
BUP microdose induction, TAU, Linkage to outpatient BUP treatment
Drug · Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Substance Use
Interventions
Family Check-up/ Individual MI, Individual and family psychoeducation
Behavioral
Lead sponsor
Brown University
Other
Eligibility
13 Years to 16 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Opioid Use, Alcohol Use Disorder
Interventions
repetitive transcranial magnetic stimulation (rTMS) for AUD, repetitive transcranial magnetic stimulation (rTMS) for OUD
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Hartford, Connecticut
Conditions
Substance Use Disorders
Interventions
Family First
Behavioral
Lead sponsor
New York University
Other
Eligibility
11 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Yoga Intervention for Substance Use and ART Adherence in Community Reentry

NCT02492893
Conditions
Substance Related Disorders, HIV
Interventions
Hatha yoga
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Opioid Use Disorder
Interventions
Trauma-informed case management for women who use drugs, CRS Only Intervention
Behavioral
Lead sponsor
Abenaa Jones, Ph.D.
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Harrisburg, Pennsylvania
Conditions
Post Traumatic Stress Disorder, Obstructive Sleep Apnea, Substance Use Disorder, Residential Treatment Program
Interventions
Positive Airway Pressure Device
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Diego, California
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Neurocognitive Predictors of Health Risk Behaviors

NCT06941181
Conditions
Substance Use
Interventions
neurocognitive tasks
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2029
U.S. locations
2
States / cities
Blacksburg, Virginia • Roanoke, Virginia
Completed Not applicable Interventional Results available

Supported Employment in Patient Aligned Care Teams

NCT02400736
Conditions
Mental Disorder, Substance Use Disorders, Posttraumatic Stress Disorder, Major Depressive Disorder, Anxiety Disorder
Interventions
Individual Placement and Support (IPS), Treatment as Usual Vocational Rehabilitation/Transitional Work (TUA-VR)
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
19 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Reducing HIV Risk Among Episodic Substance Using Men Who Have Sex With Men (SUMSM)

NCT01279044
Conditions
HIV Infections, Episodic Substance Use
Interventions
Adapted Personalized Cognitive Risk-reduction Counseling intervention (PCC), Standard HIV testing with information only
Behavioral
Lead sponsor
San Francisco Department of Public Health
Government
Eligibility
18 Years and older · Male only
Enrollment
385 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
San Francisco, California