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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Alcohol-Impaired Driving Clear all
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans

NCT01590277
View directory record Official record
Conditions
Active Ethanol and Active Iomazenil, Active Ethanol and Placebo Iomazenil, Placebo Ethanol and Active Iomazenil, Placebo Ethanol and Placebo Iomazenil, Alcohol Effect, Driving Under the Influence, Alcohol Impairment
Interventions
Active Ethanol, Active Iomazenil, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 35 Years · Male only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Interactive Text-Message Based Brief Intervention to Reduce Substance-Impaired Driving Among College Students

NCT03496129
View directory record Official record
Conditions
Alcohol-Impaired Driving
Interventions
Personalized feedback, Personalized feedback and text messages, Information Only
Behavioral
Lead sponsor
Western Kentucky University
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Bowling Green, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Phase 2 Interventional

Evaluation of an School-based Alcohol Prevention Program for Middle School Students

NCT01847183
View directory record Official record
Conditions
Alcohol-related Disorders, Drinking and Driving, Neurological Impairment
Interventions
Click City®: Alcohol
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
12 Years to 16 Years
Enrollment
2,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 5, 2016 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Smartphone-paired Breathalyzers and Loss- and Gain-framed Texts for Reducing Drinking and Driving

NCT03335735
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcohol Impairment, Drive, Driving Impaired, Driving Under the Influence, Behavior, Drinking
Interventions
Loss-framed text message, Gain-Framed text message
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 39 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project MADD - NIH Underage DUI and Ride

NCT03506880
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen
Interventions
MADD Materials, Surgeon General Materials
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
15 Years to 18 Years
Enrollment
2,352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving

NCT00559819
View directory record Official record
Conditions
Driving, Intoxication, Impairment, Alcohol Impaired Driving
Interventions
placebo, Alcohol
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 13, 2022 · Synced Jul 21, 2026, 11:46 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Neuroscience of Alcohol and Marijuana Impaired Driving

NCT03431987
View directory record Official record
Conditions
Marijuana Usage, Alcohol Drinking
Interventions
One day with a dose of placebo cannabis paired with alcohol, One day with a dose of active THC cannabis paired with alcohol
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
21 Years to 40 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 4, 2022 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cannabis Impairment Detection Application (CIDA)

NCT04230460
View directory record Official record
Conditions
Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
Interventions
Cannabis (THC) (Inhaled) Placebo, Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
Drug
Lead sponsor
Advanced Brain Monitoring, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 11, 2021 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Examine the Feasibility of a Standardized Field Test for Marijuana and Alcohol Impairment: Laboratory Evaluations

NCT04856566
View directory record Official record
Conditions
Marijuana Impairment, Alcohol Impairment
Interventions
Low Marijuana, Hash, THC, or Grass, High Marijuana, Hash, THC, or Grass, Placebo, 0.05 BAC Alcohol, 0.08 BAC Alcohol
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 40 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Validation of Alcohol Level Identification Using DRIVESC

NCT07282405
View directory record Official record
Conditions
Driving Impaired
Interventions
DRIVESC, Alcohol
Diagnostic Test · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 64 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alcohol Impaired Driving: From the Laboratory to the Natural Environment

NCT03846050
View directory record Official record
Conditions
Drinking and Driving
Interventions
BAC feedback/warning, No BAC feedback/warning
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 35 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leveraging Transdermal Alcohol Monitoring to Reduce Drinking Among DWI Defendants

NCT03638596
View directory record Official record
Conditions
Drunk Driving
Interventions
Contingency Management, Control
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years and older
Enrollment
158 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Phase 4 Interventional Results available

Vivitrol for Reducing Driving While Impaired Behavior Among Repeat Offenders

NCT00537745
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Vivitrol (Medication Therapy), Medication Management Therapy
Drug · Other
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 26, 2012 · Synced Jul 21, 2026, 11:46 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

The Rise of Ride Sharing Companies and Trends in Impaired Driving Accidents

NCT04564599
View directory record Official record
Conditions
Ride Sharing, Alcohol Drinking, Alcohol Intoxication, Drug Use, Motor Collision, Sexual Assault
Interventions
Not listed
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol Impaired Driving in the Natural Environment

NCT03503396
View directory record Official record
Conditions
Driving Under the Influence
Interventions
BAC Driving Feedback/Warning, No Feedback
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 30 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Jul 21, 2026, 11:46 AM EDT