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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:38 AM EDT

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Showing 241–264 of 1,445 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol-Related Disorders Clear all
Completed Phase 2 Interventional

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1

NCT06004830
View directory record Official record
Conditions
Alcohol Use Disorder, Hiv
Interventions
Spironolactone
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 99 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Terminated Phase 2 Interventional Results available

Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism

NCT00862563
View directory record Official record
Conditions
Alcoholism, Alcohol Dependence, Alcohol Abuse
Interventions
Topiramate, Zonisamide, Levetiracetam, Sugar Pill
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Phase 4 Interventional Results available

Understanding Treatment Response With Naltrexone Among White Alcoholics

NCT00817089
View directory record Official record
Conditions
Alcoholism
Interventions
Placebo Oral Tablet, Naltrexone
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 64 Years · Male only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 21, 2019 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting Not applicable Interventional

Mindfulness-based Relapse Prevention for Peer Workers

NCT07741825
View directory record Official record
Conditions
Relapse/Recurrence, Substance Use (Drugs, Alcohol), Burnout
Interventions
Mindfulness Based Relapse Prevention, Standard of Care
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 100 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Results available

Screening to Augment Referral to Treatment- Project START

NCT01539525
View directory record Official record
Conditions
Alcohol Abuse, Tobacco Use Disorder, Marijuana Abuse, Substance-Related Disorders
Interventions
Motivational Interview, Treatment as Usual
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
439 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 14, 2017 · Synced Oct 21, 2026, 5:38 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The ICEC Cluster Trial: Integrated Community Engagement Collaborative for Youth Substance Use Prevention in Rural America

NCT07843576
View directory record Official record
Conditions
Substance Use (Drugs, Alcohol), Tobacco Use, Adolescent Substance Use
Interventions
Integrated Community Engagement Collaborative, School-Based Data Collection and Reporting without Network Coordinator Support
Other
Lead sponsor
West Virginia University
Other
Eligibility
10 Years and older
Enrollment
25,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Not listed Phase 4 Interventional

Phenobarbital vs Ativan for Alcohol Withdrawal in the Intensive Care Unit

NCT04156464
View directory record Official record
Conditions
Alcohol Withdrawal, Alcohol Withdrawal Delirium
Interventions
Phenobarbital, Lorazepam
Drug
Lead sponsor
OSF Healthcare System
Other
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Phase 2 Interventional Results available

Improving Smoking Cessation Outcomes in Heavy Drinkers - 1

NCT00107575
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Standard treatment plus brief alcohol intervention, Standard treatment (ST)
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years to 95 Years
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 26, 2016 · Synced Oct 21, 2026, 5:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Integrated Approaches for Identifying Molecular Targets in Liver Disease

NCT03915002
View directory record Official record
Conditions
Alcoholic Liver Disease, Non-Alcoholic Fatty Liver Disease, Steatohepatitis, Nonalcoholic, Steatohepatitis
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 75 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Results available

Understanding and Intervening With Heavy Drinking Among Patients With HIV and HCV

NCT03652675
View directory record Official record
Conditions
Alcohol Use Disorder, HIV/AIDS, Hepatitis C, Binge Drinking
Interventions
Intervention: (Clinician's Guide + HealthCall for HIV/HCV)
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 99 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 23, 2021 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Phase 1 Interventional

Individualized Treatment Program for Alcohol Problems

NCT00298792
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Cognitive-behavioral treatment
Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 15, 2009 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stress-motivated Alcohol Use as a Value-based Decision-making Process

NCT06264791
View directory record Official record
Conditions
Psychological Stress, Alcohol Intoxication
Interventions
Stress, Alcohol
Other
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 50 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional

Treatment for Teens With Alcohol Abuse and Depression

NCT02227589
View directory record Official record
Conditions
AOD Use, Abuse, and Dependence, Depression
Interventions
MET/CBT-12, CBT-D, D-TAU
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
13 Years to 263 Months
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
2
States / cities
Farmington, Connecticut • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 21, 2026, 5:38 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Computerized Screening and Brief Physician Advice to Reduce Teen Drinking

NCT00849589
View directory record Official record
Conditions
Alcohol Abuse, Risk Behavior
Interventions
Computerized screening and brief physician advice, Computerized SBA with technological extenders
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2016 · Synced Oct 21, 2026, 5:38 AM EDT
Not listed Not applicable Interventional

Neurophysiological Mechanisms of Accelerated Resolution Therapy (ART)

NCT04121884
View directory record Official record
Conditions
Depressive Symptoms, Stress Disorder, Acute, Prolonged Grief Disorder, Alcohol Abuse, Stress Disorders, Post-Traumatic
Interventions
Accelerated Resolution Therapy
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Phase 3 Interventional

Motivational Interviewing for Alcohol-Positive Teens in the Emergency Room

NCT00246428
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence
Interventions
Individual Motivational Interview (IMI), Individual Motivational Interview + Family Check-Up
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 24 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Not yet recruiting Phase 2 Interventional

Daridorexant for People With Insomnia and Alcohol Use Disorder Study

NCT07701928
View directory record Official record
Conditions
Alcohol Use Disorder, Insomnia
Interventions
Daridorexant, Placebo, Brief Counseling, MEMS and Medication Accounting, Contingency Management for Medication Adherence
Drug · Behavioral · Device
Lead sponsor
Sterling McPherson
Other
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Not yet recruiting Not applicable Interventional

A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerging Adults

NCT07214831
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Large language model-based chatbot brief alcohol intervention session
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 29 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Terminated Not applicable Interventional

Targeting Non-virally Suppressed Adults With Alcohol Use Disorder in HIV Primary Care

NCT04280068
View directory record Official record
Conditions
Alcohol Dependence, HIV/AIDS
Interventions
Clinician Guide (CG), Clinician Guide plus HealthCall
Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2020 · Synced Oct 21, 2026, 5:38 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The "Prediction of Alcohol Withdrawal Severity Scale" (PAWSS)

NCT01637415
View directory record Official record
Conditions
Alcohol Withdrawal Syndrome
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
409 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2015 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Results available

Project IMPACT: In-the-Moment Protection From Automatic Capture by Trigger

NCT02579317
View directory record Official record
Conditions
Substance Use Disorder
Interventions
Resonance Breathing, Non-Resonance Breathing
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older · Female only
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Family-Based Alcohol Prevention

NCT00858065
View directory record Official record
Conditions
Alcohol Abuse, Drug Abuse
Interventions
Strengthening Families Program (SFP), Family Matters
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
11 Years to 12 Years
Enrollment
1,228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
2
States / cities
Berkeley, California • Oakland, California
Source: ClinicalTrials.gov public record
Updated Sep 29, 2021 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Phase 1b Study of DCR-AUD in Healthy Volunteers

NCT05845398
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
DCR-AUD, Placebo
Drug
Lead sponsor
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Industry
Eligibility
21 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Glendale, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting Not applicable Interventional

Sensory and Physical Reactions to Beverage Cues

NCT07788716
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Alcohol Cue Reactivity Paradigm
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 21, 2026, 5:38 AM EDT