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ClinicalTrials.gov public records Last synced Oct 22, 2026, 9:22 AM EDT

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Showing 457–480 of 1,446 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol-Related Disorders Clear all
Completed Phase 2 Interventional Results available

Pregabalin as Treatment for Alcohol Use Disorder

NCT03256253
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Pregabalin
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 31, 2020 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Phase 4 Interventional

Treatment of Patients With Alcoholism and Attention Deficit Disorder

NCT00261872
View directory record Official record
Conditions
Alcoholism, Attention Deficit Disorder
Interventions
Methylphenidate
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Substance Treatment and HIV Testing and Referral System

NCT01488630
View directory record Official record
Conditions
Substance Abuse
Interventions
STaRS
Other
Lead sponsor
Polaris Health Directions
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Oct 22, 2026, 9:22 AM EDT
Recruiting Not applicable Interventional

tAN for Substance Use Disorder

NCT07281261
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Abuse, Substance Use Disorders, Substance Use Disorders Alcohol Use Withdrawal State
Interventions
Sparrow Ascent, Sparrow Ascent (Sham)
Device
Lead sponsor
Spark Biomedical, Inc.
Industry
Eligibility
18 Years to 64 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Phase 2 Interventional

Oxytocin to Enhance Integrated Treatment for AUD and PTSD

NCT04523922
View directory record Official record
Conditions
PTSD, Alcohol Use Disorder
Interventions
40 IU Intranasal Oxytocin, Placebo, Concurrent Treatment of PTSD and Substance Use Disorders using Prolonged Exposure
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Phase 2 Interventional

Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13

NCT00000261
View directory record Official record
Conditions
Alcohol-Related Disorders, Opioid-Related Disorders, Substance-Related Disorders
Interventions
30% Nitrous oxide, Placebo, 0.2% sevoflurane, 0.4% sevoflurane, 0.6% sevoflurane
Drug · Other
Lead sponsor
University of Chicago
Other
Eligibility
Not listed
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 1998
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Oct 22, 2026, 9:22 AM EDT
Recruiting Not applicable Interventional

Mechanisms of Risky Alcohol Use in Young Adults: Linking Sleep to Reward- and Stress-Related Brain Function

NCT05684094
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Sleep extension and advance, Regular sleep duration and timing
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 24 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 22, 2026, 9:22 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The STop UNhealthy Substance Use Now Trial

NCT06524232
View directory record Official record
Conditions
Risky Health Behavior, Substance Use Disorders, Substance Abuse, Alcohol Use Disorder, Drinking, Alcohol, Substance Use
Interventions
Practice Facilitation (PF), Learning Collaborative (LC), Performance Incentives (PI)
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
3
States / cities
Cincinnati, Ohio • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 22, 2026, 9:22 AM EDT
Terminated Phase 2 Interventional Results available

Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism

NCT00862563
View directory record Official record
Conditions
Alcoholism, Alcohol Dependence, Alcohol Abuse
Interventions
Topiramate, Zonisamide, Levetiracetam, Sugar Pill
Drug
Lead sponsor
Boston Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 22, 2026, 9:22 AM EDT
Withdrawn No phase listed Observational

Computerized Alcohol Screening for Children and Adolescents

NCT01539954
View directory record Official record
Conditions
Alcohol Related Disorders
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
9 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2016 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Not applicable Interventional

Ultrabrief Behavioral Activation for Reducing Alcohol Use

NCT05086172
View directory record Official record
Conditions
Alcohol Use Disorder, Mild, Alcohol Use Disorder, Moderate
Interventions
Ultrabrief Behavioral Activation
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 22, 2026, 9:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)

NCT00579267
View directory record Official record
Conditions
Major Depression, Mania, Anxiety Disorders, Psychotic Disorder, Alcohol Dependence, Drug Dependence, Eating Disorders, Suicidality, Dysthymia, ADHD, Tourettes Disorder, Conduct Disorder, Oppositional Defiant Disorder, Pervasive Developmental Disorder
Interventions
MINI-KID
Other
Lead sponsor
University of South Florida
Other
Eligibility
6 Years to 17 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 16, 2009 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Development of Ivermectin for Alcohol Use Disorders

NCT02046200
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Ivermectin, Placebo, Alcohol
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Oct 22, 2026, 9:22 AM EDT
Recruiting Not applicable Interventional

CIFASD 5 tDCS and Cognitive Training

NCT05456321
View directory record Official record
Conditions
Fetal Alcohol Spectrum Disorders
Interventions
Active tDCS, Cognitive Training, Sham tDCS
Device · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
8 Years to 17 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 22, 2026, 9:22 AM EDT
Withdrawn Phase 3 Interventional

The Use of Anticonvulsants for Treatment of Patients With Alcohol Dependence and Post Traumatic Stress Disorder

NCT00571246
View directory record Official record
Conditions
Alcohol Dependence, Post Traumatic Stress Disorder
Interventions
Topiramate, lamotrigine, Placebo
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Clinical Trial for Alcohol Use Disorder and Post Traumatic Stress Disorder (PTSD)

NCT02966873
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD), Addiction, Alcohol Abuse
Interventions
N-Acetylcysteine (NAC) Treatment, Cognitive Behavioral Therapy (CBT), Inactive Placebo Oral Capsule, Functional magnetic resonance imaging (fMRI), Proton magnetic resonance spectroscopy (MRS) Imaging
Drug · Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 22, 2026, 9:22 AM EDT
Not listed Not applicable Interventional

Divalproex Sodium for Mood Swings and Alcohol Use Following Head Injury.

NCT01326663
View directory record Official record
Conditions
Veterans, TBI, Alcoholism, Irritable Mood
Interventions
Medication Trial
Drug
Lead sponsor
Paul Saenger
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 7, 2012 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Not applicable Interventional

Stress Reactivity in Veterans Receiving Pharmacological Treatment for PTSD and Alcohol Dependence

NCT00923923
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Alcohol Dependence
Interventions
stress
Behavioral
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 14, 2016 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Mindfulness for Alcohol Use and PTSD Among Veterans

NCT04769986
View directory record Official record
Conditions
Alcohol Use Disorder, Posttraumatic Stress Disorder
Interventions
Mobile Mindfulness-Relapse Prevention (mMBRP), Exercise/healthy eating mobile app
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
201 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
3
States / cities
Los Angeles, California • Menlo Park, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Phase 2 Interventional

Medical Office Intervention for Adolescent Drug Use

NCT00229983
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Motivational Enhancement Therapy
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 21 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2016 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Impact of a Brief Motivational Interview on Drinking Behaviors of At Risk Drinkers Screened in the Emergency Room

NCT00183183
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Screening and Brief Intervention
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Enrollment
1,137 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
15
States / cities
Los Angeles, California • San Diego, California • Denver, Colorado + 10 more
Source: ClinicalTrials.gov public record
Updated May 24, 2010 · Synced Oct 22, 2026, 9:22 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

NCT06552741
View directory record Official record
Conditions
Substance Use Disorder, Alcohol Use Disorder
Interventions
Not listed
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 99 Years
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2047
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Changing Impulsivity With Mindful Breathing Therapy to Reduce Problem Drinking

NCT02527720
View directory record Official record
Conditions
Problem Drinking
Interventions
Mindfulness Therapy
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 30 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 13, 2019 · Synced Oct 22, 2026, 9:22 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Placebo-Controlled Cross Over Trial of Chlorzoxazone Intake

NCT01342341
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Parafon Forte
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 50 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Emeryville, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2020 · Synced Oct 22, 2026, 9:22 AM EDT