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Showing 553–576 of 1,446 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Broccoli Extract Supplementation in Older Adults With Alcohol Use Disorder

NCT05902754
Conditions
Alcohol Use Disorder
Interventions
Generally Recognized as Safe - Sulforaphane, Placebo
Dietary Supplement
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
50 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Marijuana's Impact on Alcohol Motivation and Consumption

NCT02983773
Conditions
Alcohol Drinking, Marijuana
Interventions
THC 7.2%, THC 3.1%, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
21 Years to 44 Years
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Alcoholism
Interventions
Sugar Pill, TRICOR (fenofibrate)
Drug
Lead sponsor
The Scripps Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
La Jolla, California
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Alcohol Use and Mental Health - Pilot Test of Video-assisted Drinking Topography

NCT03314454
Conditions
Alcohol Use Disorder
Interventions
Beer, Videotaped drinking session
Drug · Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional Results available

Efficacy and Mechanisms of CBT4CBT for Alcohol Use Disorders

NCT02742246
Conditions
Alcohol Use Disorder
Interventions
Individual clinician-provided CBT, CBT4CBT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
2
States / cities
Bridgeport, Connecticut • New Haven, Connecticut
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcoholism
Interventions
Brain stimulation with mindfulness-based relapse prevention
Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Albuquerque, New Mexico
Conditions
Head and Neck Cancer, Alcohol Use, Unspecified
Interventions
Alcohol Cessation Text Messages, Usual Care
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Manhasset, New York
Conditions
Alcohol Use, Posttraumatic Stress Disorder
Interventions
CBT Text Messages, Supportive Messages
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
333 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Alcohol Abuse, Posttraumatic Stress Disorder
Interventions
Prazosin, Placebo medication
Drug
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Alcohol Abuse, Cannabis Abuse, Major Depressive Disorder, Substance-Related Disorders
Interventions
Integrated Cognitive Behavioral Therapy, Twelve Step Facilitation Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
San Diego, California
Conditions
Alcohol Dependence, Binge Eating
Interventions
Topiramate
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
2
States / cities
Charlottesville, Virginia • Richmond, Virginia
Conditions
Alcohol; Use, Problem, Posttraumatic Stress Disorder
Interventions
Imaginal Exposure, Alcohol Skills Training, Supportive Telehealth
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Alcohol Use Disorder, Mild Traumatic Brain Injury
Interventions
VR-WMR-Only, Exercise-only, Active VR-WMR
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Conditions
Bipolar Disorder, Alcohol Use Disorder
Interventions
Adherence therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Alcohol Use Disorders
Interventions
Cognitive-behavioral treatment
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 65 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Completed Phase 4 Interventional Results available

Naltrexone for Heavy Drinking in Young Adults

NCT00568958
Conditions
Alcohol Consumption, Alcoholic Intoxication, Alcoholism, Alcohol-induced Disorders
Interventions
BASICS counseling, naltrexone, placebo naltrexone
Behavioral · Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 25 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Phase 2 Interventional Results available

Varenicline for Alcohol Dependence

NCT01146613
Conditions
Alcoholism
Interventions
Varenicline, Placebo
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
7
States / cities
Baltimore, Maryland • Boston, Massachusetts • Bedford, New Hampshire + 4 more
Conditions
Alcohol Dependence
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Alcohol Dependence, Alcoholism, Drug Dependence
Interventions
Chronic Disease Management for substance abuse, Standard care
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
569 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Alcoholism, Alcohol Dependence, Posttraumatic Stress Disorder
Interventions
Aprepitant, Placebo
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 50 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol, Marijuana, and Risky Sex: Group Interventions With Detained Adolescents

NCT01170260
Conditions
Risk Reduction Behavior, Health Behavior, Sexual Behavior, Adolescent Behavior, Cannabis
Interventions
INFORMATION-ONLY SEXUAL RISK REDUCTION (INFO-ONLY), SEXUAL PLUS ALCOHOL RISK REDUCTION (SRRI+ETOH), SEXUAL + ALCOHOL + MARIJUANA RISK REDUCTION
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
14 Years to 18 Years
Enrollment
460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Albuquerque, New Mexico
Conditions
Substance Use Disorders
Interventions
Integrated collaborative care, Education and Resources
Other
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
397 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
2
States / cities
Santa Monica, California • Venice, California
Conditions
Alcohol Intoxication
Interventions
Not listed
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
668 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

INIA Stress and Chronic Alcohol Interactions: Glucocorticoid Antagonists in Heavy Drinkers

NCT02989662
Conditions
Alcohol Use Disorder
Interventions
Mifepristone, Placebo - Cap
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 55 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland