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ClinicalTrials.gov public records Last synced Oct 23, 2026, 5:31 AM EDT

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Showing 601–624 of 1,446 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol-Related Disorders Clear all
Completed No phase listed Observational Results available

Implementing a Blended Care Model That Integrates Mental Healthcare and Primary Care Using Telemedicine and Care Management for Patients With Depression or Alcohol Use Disorder in Small Primary Care Clinics

NCT02713217
View directory record Official record
Conditions
Depressive Disorders, Alcohol Use Disorders, Post-traumatic Stress Disorder (PTSD)
Interventions
Usual Care, Blended Telemedicine-Based Integrated Care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
318 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
North Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Online Insomnia Intervention to Reduce Alcohol Use

NCT05630118
View directory record Official record
Conditions
Alcohol Use Disorder, Heavy Drinking
Interventions
SHUTi Intervention, Web-Based Insomnia Education Program
Behavioral
Lead sponsor
Jessica Weafer
Other
Eligibility
18 Years to 50 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Phase 2 Interventional

Ondansetron Treatment for Alcoholism

NCT00000443
View directory record Official record
Conditions
Alcoholism
Interventions
ondansetron (Zofran)
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
25 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2000
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 23, 2026, 5:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Recovery Inspired Support Engagement (RISE) Pilot

NCT07519759
View directory record Official record
Conditions
Support Persons, Family Members, Chosen Family, Romantic Partners, Friends, Caregivers, Substance Use Disorders
Interventions
ITC
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 23, 2026, 5:31 AM EDT
Active, not recruiting Not applicable Interventional Results available

Addressing Barriers to Care for Substance Use Disorder Pilot Study

NCT06317987
View directory record Official record
Conditions
Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
Interventions
Care Navigation
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 23, 2026, 5:31 AM EDT
Recruiting Not applicable Interventional

Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity

NCT05117255
View directory record Official record
Conditions
Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Alcohol Use Disorder, Depression
Interventions
Negative Emotions and Addiction Tools Program (NEAT)- Cognitive Behavioral Therapy, Progressive Muscle Relaxation Training (PMRT)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Neuroimmune Dysfunction in Alcohol Use Disorder

NCT04210713
View directory record Official record
Conditions
Alcohol Drinking, Alcohol-Related Disorders, Disease, Inflammation, Alcoholism, Cognitive Dysfunction, Pathologic Processes, Drinking Behavior, Substance-Related Disorders, Chemically-Induced Disorders, Mental Disorder, Cognition Disorder, Neurocognitive Disorders, Minocycline, Anti-Bacterial Agents, Anti-Infective Agents
Interventions
Minocycline, Sugar pill
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
25 Years to 65 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 1, 2023 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Phase 2 Interventional

Study of Sunobinop on Craving in Alcohol Use Disorder

NCT06545929
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Sunobinop, Placebo to match sunobinop
Drug
Lead sponsor
Knoa Pharma LLC
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Not applicable Interventional Results available

Primary Care Treatment Integrating Motivation and Exposure

NCT03812146
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Alcohol-Related Disorders
Interventions
PC-TIME, PC-TAU
Behavioral
Lead sponsor
Syracuse VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Buffalo, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Oct 23, 2026, 5:31 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Neurosteroids and Acute Alcohol Intoxication in Humans

NCT00608686
View directory record Official record
Conditions
Alcohol Intoxication
Interventions
Pregnenolone
Dietary Supplement
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 45 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 19, 2008 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Personalized Drinking Feedback Interventions

NCT01211353
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Personalized Drinking Feedback, Education-Only
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 80 Years
Enrollment
325 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 16, 2017 · Synced Oct 23, 2026, 5:31 AM EDT
Recruiting Not applicable Interventional

Adaptation and Evaluation of Bright Horizons

NCT05743699
View directory record Official record
Conditions
Alcohol Abuse, Substance Use
Interventions
Bright Horizons, Case Management
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
10 Years to 24 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Phase 1Phase 2 Interventional Results available

N-acetylcysteine in Alcohol Dependence

NCT00568087
View directory record Official record
Conditions
Alcoholism
Interventions
N-acetylcysteine, Placebo
Drug
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Phase 2 Interventional Results available

Study of the Effectiveness of Quetiapine for the Treatment of Alcohol Dependency

NCT00498628
View directory record Official record
Conditions
Alcoholism, Alcohol Abuse
Interventions
Quetiapine fumarate, Placebo
Drug · Other
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
7
States / cities
Boston, Massachusetts • Lebanon, New Hampshire • Philadelphia, Pennsylvania + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Early Phase 1 Interventional Results available

Pilot Study on Mindfulness for Tobacco and Alcohol in University Students

NCT01679236
View directory record Official record
Conditions
Nicotine Dependence, Alcohol Use
Interventions
Mindfulness Training for Smokers, Interactive Learning for Smokers
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 29 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 24, 2014 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Not applicable Interventional

Early Intervention Following Sexual Assault

NCT04582695
View directory record Official record
Conditions
Ptsd, Alcohol Use Disorder, Sexual Assault and Rape
Interventions
Written Exposure Therapy Integrated with Cognitive Behavioral Therapy for Alcohol Use Disorder, Written Exposure Therapy
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 23, 2026, 5:31 AM EDT
Recruiting Not applicable Interventional

Thrive Person-Centered Planning Program for Young Adults With Fetal Alcohol Spectrum Disorders

NCT07016009
View directory record Official record
Conditions
Fetal Alcohol Spectrum Disorders
Interventions
Thrive Program
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 25 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Not applicable Interventional Results available

Examining the Effectiveness of Deep TMS in Veterans With Alcohol Use Disorder

NCT04927364
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), Transcranial Magnetic Stimulation
Interventions
Deep Transcranial Magnetic Stimulation (dTMS) H7 coil
Device
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
21 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Phase 3 Interventional

Naltrexone in Two Models of Psychosocial Treatments for Cocaine and Alcohol Dependence

NCT00167232
View directory record Official record
Conditions
Cocaine Dependence, Alcoholism
Interventions
Naltrexone
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2003
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 28, 2018 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Phase 2 Interventional Results available

Seroquel for Frequent, Heavy Drinkers

NCT00674765
View directory record Official record
Conditions
Alcoholism
Interventions
Seroquel, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 70 Years
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 17, 2014 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Phosphatidylethanol-Based Contingency Management for Housing

NCT04038021
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Phosphatidylethanol-based Contingency Management, Non-Contingent Control
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Not applicable Interventional

A Brief Intervention for Alcohol Users With Interpersonal Trauma

NCT05414344
View directory record Official record
Conditions
Heavy Drinking, Alcohol Drinking, Substance Use, Drinking Behavior
Interventions
Standard Brief Intervention, Trauma-Informed and Peer-Supported Brief Intervention, Assessment only
Behavioral
Lead sponsor
Western Kentucky University
Other
Eligibility
18 Years to 25 Years
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Bowling Green, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 23, 2026, 5:31 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Supporting Adolescent Alcohol Treatment With Computer-Based ('Path180') Skills Training

NCT07713251
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Path180
Behavioral
Lead sponsor
Brown University
Other
Eligibility
13 Years to 19 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 23, 2026, 5:31 AM EDT
Completed Phase 2 Interventional

The iHealth Study in College Students

NCT00183131
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence, Unhealthy Alcohol Use, Risky Alcohol Consumption Amounts, Hazardous Alcohol Use
Interventions
Brief Personalized Feedback
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
4,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 6, 2010 · Synced Oct 23, 2026, 5:31 AM EDT