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Showing 625–648 of 1,446 matching trials from the live ClinicalTrials.gov search.
Conditions
Aggression, Substance-Related Disorders
Interventions
MI-CBT, MI-CBT+CC, E-TAU
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Bipolar I Disorder, Alcohol Dependence
Interventions
Quetiapine fumarate, lithium, divalproex
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
21 Years to 60 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
38
States / cities
Cerritos, California • San Diego, California • New Haven, Connecticut + 35 more
Conditions
Alcohol Use Disorder
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Antonio, Texas
Completed No phase listed Observational Accepts healthy volunteers

Epi-Genetic Modulators of Fear Extinction in Alcohol Dependence

NCT02438969
Conditions
Fear, Stress, Alcohol Dependence
Interventions
Not listed
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Alcohol Use Disorder, Liver Diseases
Interventions
DALC Digital Clinic
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Scottsdale, Arizona • Rochester, Minnesota
Conditions
HIV, Alcohol Use Disorder
Interventions
Relapse Prevention Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

Text-based Alcohol Prevention for First Year College Students

NCT03864237
Conditions
College Drinking
Interventions
Alcohol texts, Attention control
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 20 Years
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Breast Cancer, Alcohol Drinking
Interventions
Sobriety Digital Intervention
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
40 Years and older · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Miami, Florida
Conditions
Major Depression, Mania, Anxiety Disorders, Psychotic Disorder, Alcohol Dependence, Drug Dependence, Eating Disorders, Suicidality, Dysthymia, ADHD, Tourettes Disorder, Conduct Disorder, Oppositional Defiant Disorder, Pervasive Developmental Disorder
Interventions
MINI-KID
Other
Lead sponsor
University of South Florida
Other
Eligibility
6 Years to 17 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Tampa, Florida
Recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Blood Pressure in Mid-life Adult Binge Drinkers

NCT05522075
Conditions
Alcohol Drinking, Binge Drinking, Blood Pressure, Alcohol Abstinence, Aging, Lifestyle Factors, Vasodilation, Behavioral Problem
Interventions
Exercise Training, Alcohol Abstinence Intervention
Behavioral
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
50 Years to 64 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Arlington, Texas
Conditions
Alcohol Use Disorder
Interventions
Cervical transcutaneous vagus nerve stimulation (active comparator), Cervical transcutaneous vagus nerve stimulation (sham comparator)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 65 Years · Male only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Diego, California
Conditions
Bipolar Disorder, Alcohol Use Disorder
Interventions
Adherence therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Alcohol Dependence
Interventions
Naltrexone, Naltrexone plus Gabapentin, Inactive Placebo
Drug · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Mentored Research on Improving Alcohol Brief Interventions in Medical Settings

NCT02978027
Conditions
Alcohol Abuse
Interventions
Brief Advice, NIAAA Clinician's Guide, Motivational Interviewing (MI)
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Albuquerque, New Mexico
Conditions
Bipolar Disorder
Interventions
Senyo Health App
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Tobacco Use Disorder
Interventions
Tobacco Use Disorder
Behavioral
Lead sponsor
Inflexxion, Inc.
Industry
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
7
States / cities
La Puente, California • Athol, Massachusetts • Ann Arbor, Michigan + 4 more
Conditions
Alcohol Use Disorder, Harm Reduction, Housing First (eg. Permanent Supportive Housing)
Interventions
eHaRT-A
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
21 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers

Michigan SPARC Trial

NCT04861792
Conditions
Alcohol, Drinking, Alcohol Use Disorder (AUD)
Interventions
Michigan SPARC Quality Improvement Intervention
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
9,590 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Enrolling by invitation Not applicable Interventional

Personalizing Treatment Delivery

NCT05821634
Conditions
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
Interventions
Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Conditions
Alcohol Use Disorder
Interventions
In-Hospital Recovery Coach Intervention
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Alcoholism
Interventions
acamprosate
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
485 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Rochester, Minnesota
Recruiting Not applicable Interventional Accepts healthy volunteers

Native Spirit: Significant Aim 3: Intervention

NCT06785311
Conditions
Substance Use, Self Esteem, Youth Drinking, Prevention, Suicide
Interventions
Native Spirit After-School Program
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Scottsdale, Arizona • Tucson, Arizona
Conditions
Alcohol Related Disorders
Interventions
acetaminophen
Drug
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2004
U.S. locations
2
States / cities
Denver, Colorado • Seattle, Washington
Completed No phase listed Observational

Study of Structural Imaging

NCT02564991
Conditions
Chemically-Induced Disorders, Substance-Related Disorders, Mental Disorders, Alcohol Dependence, Alcohol-Related Disorders
Interventions
Not listed
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
30 Years to 60 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland