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ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:59 PM EDT

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Showing 721–744 of 1,446 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol-Related Disorders Clear all
Completed Early Phase 1 Interventional Results available

Inpatient Single Dose Interventions for Alcohol Use Disorder

NCT04562779
View directory record Official record
Conditions
Alcohol Use Disorder, Severe
Interventions
Naltrexone 380 MG, Ketamine Hydrochloride, Enhanced linkage
Drug · Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Neurocognitive Habilitation for Children With Fetal Alcohol Syndrome (FAS)/Alcohol-Related Neurodevelopmental Disorder (ARND)

NCT00164346
View directory record Official record
Conditions
Fetal Alcohol Syndrome, Alcohol-related Neurodevelopmental Disorder
Interventions
neurocognitive habilitation
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
6 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 24, 2011 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Phase 3 Interventional Results available

Treatment With Acamprosate in Patients With Schizophrenia and Comorbid Alcoholism

NCT00463346
View directory record Official record
Conditions
Alcohol Dependence, Schizophrenia
Interventions
Acamprosate, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 31, 2020 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Cannabidiol in Youth Alcohol Use Disorder

NCT05317546
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Cannabidiol
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
16 Years to 22 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Phase 4 Interventional Results available

Baclofen to Reduce Alcohol Use in Veterans With HCV

NCT01008280
View directory record Official record
Conditions
Hepatitis C, Alcohol Use Disorders
Interventions
baclofen, placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
4
States / cities
Long Beach, California • San Diego, California • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2016 · Synced Oct 23, 2026, 8:59 PM EDT
Recruiting Not applicable Interventional

Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

NCT05910580
View directory record Official record
Conditions
Alcohol-Related Disorders, Substance-Related Disorders, Mental Health, Reproductive Health, Sexual Health, Sexually Transmitted Diseases, Contraception, Maternal Health, Pregnancy, Women's Health
Interventions
Screening, Brief Intervention, and Referral to Treatment (SBIRT)
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Boston, Massachusetts • Marlborough, Massachusetts • Springfield, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Phase 2 Interventional Results available

An Exploratory Study of Naltrexone Plus Aripiprazole for Alcohol Dependence

NCT00667875
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Placebo, Naltrexone, Naltrexone + Aripiprazole
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 29, 2017 · Synced Oct 23, 2026, 8:59 PM EDT
Recruiting Not applicable Interventional

Reset Challenge: Reducing High-risk Drinking for Cancer Prevention

NCT07591428
View directory record Official record
Conditions
Alcohol Drinking, Heavy Drinking, Binge Drinking
Interventions
30-Day Alcohol Abstinence Challenge
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 120 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 23, 2026, 8:59 PM EDT
Recruiting Phase 1 Interventional

Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)

NCT07559500
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Tirzepatide, Placebo, [11C]raclopride plus drug, [11C]NNC-112
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 65 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Phase 2 Interventional Results available

Topiramate for Alcohol and Cocaine Dependence

NCT00167245
View directory record Official record
Conditions
Alcoholism, Cocaine Dependence
Interventions
Topiramate, placebo
Drug
Lead sponsor
Kyle Kampman
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Broccoli Extract Supplementation in Older Adults With Alcohol Use Disorder

NCT05902754
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Generally Recognized as Safe - Sulforaphane, Placebo
Dietary Supplement
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
50 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Phase 4 Interventional

Trial of Seroquel SR for Alcohol Dependence and Comorbid Anxiety

NCT00352469
View directory record Official record
Conditions
Alcoholism, Anxiety Disorders, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, Panic Disorder, Obsessive-Compulsive Disorder
Interventions
Seroquel XR
Drug
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 8, 2008 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Not applicable Interventional

Enhancing Prospective Thinking in Early Recovery (NERF)

NCT06283446
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
High-Intensity Cue, Low-Intensity Cue
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 60 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 23, 2026, 8:59 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

MATAspire: Mental Health Awareness Tailored App for Substance Prevention and Integrated Resilience Education

NCT06553196
View directory record Official record
Conditions
Alcohol Use, Cannabis Use, Nicotine Use, Illicit Drug Use, Prescription Opioid Misuse
Interventions
MATAspire Web-app
Behavioral
Lead sponsor
California State University, Northridge
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Northridge, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Building Recovery By Improving Goals, Habits, and Thoughts

NCT01191788
View directory record Official record
Conditions
Depression, Substance Use
Interventions
Group Cognitive Behavioral Therapy, Group CBT for Depression
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
299 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Gardena, California
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Housing First Programs With a Social Network Substance Use Intervention

NCT02140359
View directory record Official record
Conditions
Alcohol Drinking, Drug Abuse, HIV
Interventions
Motivational Network Interview
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
Los Angeles, California • Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Nov 24, 2017 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Phase 4 Interventional

The Whole Day First Grade Program

NCT00257088
View directory record Official record
Conditions
Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency, High Risk Sex Behavior, Smoking Tobacco, School Failure
Interventions
whole day first grade program
Behavioral
Lead sponsor
American Institutes for Research
Other
Eligibility
Not listed
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 14, 2008 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Early Phase 1 Interventional Results available

Pentoxifylline Treatment of Acute Pancreatitis

NCT01292005
View directory record Official record
Conditions
Acute Pancreatitis
Interventions
Pentoxifylline, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Not applicable Interventional

Cerebellar Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Alcohol Use Disorder

NCT03829761
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Repetitive transcranial magnetic stimulation (rTMS), Sham transcranial magnetic stimulation
Device
Lead sponsor
The Mind Research Network
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Phase 4 Interventional Results available

Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

NCT02582905
View directory record Official record
Conditions
Alcohol Use Disorder, Bipolar Disorder, Schizoaffective Disorder Bipolar Type
Interventions
Placebo, Citicoline, Pregnenolone
Drug · Dietary Supplement
Lead sponsor
Sherwood Brown, MD, PhD
Other
Eligibility
18 Years to 70 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
3
States / cities
Miami, Florida • Dallas, Texas • Edinburg, Texas
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)

NCT04331288
View directory record Official record
Conditions
Potential Treatment for Alcohol Dependence-Alcohol Interaction
Interventions
PT150, Beverage
Drug · Other
Lead sponsor
Pop Test Oncology LLC
Industry
Eligibility
21 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2023 · Synced Oct 23, 2026, 8:59 PM EDT
Completed Not applicable Interventional

E-Health Coping Skills Training for Women Whose Partner Has a Drinking Problem

NCT02984241
View directory record Official record
Conditions
Alcohol Abuse
Interventions
eHealth Coping Skills Training, eHealth Usual Web Care, Coach Support
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older · Female only
Enrollment
456 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 23, 2026, 8:59 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Alcohol Use and Mental Health - Pilot Test of Video-assisted Drinking Topography

NCT03314454
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Beer, Videotaped drinking session
Drug · Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 55 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Oct 23, 2026, 8:59 PM EDT
Recruiting Not applicable Interventional

Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease

NCT06305624
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol-related Liver Disease
Interventions
Connections App
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
298 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Lansing, Michigan • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 23, 2026, 8:59 PM EDT