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ClinicalTrials.gov public records Last synced Oct 26, 2026, 4:41 AM EDT

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Showing 961–984 of 1,446 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol-Related Disorders Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk Behaviors

NCT04360018
View directory record Official record
Conditions
Alcohol Consumption
Interventions
Alcohol beverage, Placebo beverage
Other
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Phase 2 Interventional

Safety of Acamprosate in Treating Alcohol Use Disorder in the Post Liver Transplant Populations

NCT06471686
View directory record Official record
Conditions
Alcohol Use Disorder, Liver Transplant; Complications
Interventions
Acamprosate
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2024 · Synced Oct 26, 2026, 4:41 AM EDT
Active, not recruiting No phase listed Observational

Observational Pilot Study to Explore the Social and Health Impacts of a New Model of Care in Oregon: Psilocybin Services on Alcoholism

NCT07189988
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
psilocybin
Other
Lead sponsor
Healing Advocacy Fund
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Oct 26, 2026, 4:41 AM EDT
Recruiting Phase 2Phase 3 Interventional

MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder

NCT07118839
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Alcohol Use Disorder
Interventions
Full Dose MDMA, MDMA-Assisted psychotherapy, Active Placebo Dose MDMA
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
West Haven, Connecticut • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Phase 2 Interventional

New Medications to Treat Alcohol Dependence

NCT00223639
View directory record Official record
Conditions
Alcoholism
Interventions
Topiramate
Drug
Lead sponsor
Bankole Johnson
Other
Eligibility
21 Years to 45 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
2
States / cities
Charlottesville, Virginia • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 7, 2012 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Not applicable Interventional

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients

NCT01671501
View directory record Official record
Conditions
HIV, Acquired Immunodeficiency Syndrome, Alcoholism, Alcoholic Intoxication, Substance-Related Disorders
Interventions
Motivational Interviewing, Email Feedback, Usual Care
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
614 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Psychosocial and Medication Treatment for Anxiety in Alcoholism

NCT00248612
View directory record Official record
Conditions
Alcohol-Related Disorders, Anxiety Disorders
Interventions
Venlafaxine, CBT, Progressive muscle relaxation therapy (PMR), Placebo medication
Drug · Behavioral · Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Phase 2 Interventional Results available

A Study in the Treatment of Alcohol Dependence.

NCT00805441
View directory record Official record
Conditions
Alcohol Dependence
Interventions
LY686017, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
21 Years to 65 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
21
States / cities
Oceanside, California • San Diego, California • Deerfield Beach, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2019 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Oxytocin Treatment of Alcohol Dependence

NCT02251912
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Intranasal Oxytocin, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Not applicable Interventional

Effects of tDCS Paired With Cognitive Training on Brain Networks Associated With Alcohol Use Disorder in Veterans

NCT04574167
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Phase 4 Interventional Results available

Extended-release Naltrexone and Care Management for Alcohol Dependent Frequent Emergency Department Users

NCT02445339
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Use Disorder
Interventions
XR-NTX+CM (Extended-Release Naltrexone plus Care Management)
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Not applicable Interventional

Theta Burst Stimulation as a Tool to Decrease Drinking in Treatment-seeking Alcohol Users

NCT04154111
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Abuse, Alcohol Dependence, Craving
Interventions
Real TBS to the vmPFC, Sham TBS to the vmPFC, Real TBS to the dlPFC, Sham TBS to the dlPFC
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 75 Years
Enrollment
147 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Not applicable Interventional

Behavioral and Functional Task Development, Implementation, and Testing

NCT02108054
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Drinking, Alcoholism, Alcohol Use Disorder, Addiction
Interventions
7T MRI
Device
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 26, 2026, 4:41 AM EDT
Not yet recruiting Phase 2 Interventional

Psilocybin-Assisted Psychotherapy for the Treatment of Severe Alcohol Use Disorder

NCT07296094
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Psilocybin
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Not applicable Interventional Results available

Scaling Up: A Multi-Site Trial of e-SBI for Alcohol Use in Pregnancy

NCT04332172
View directory record Official record
Conditions
Fetal Alcohol Spectrum Disorders, Fetal Alcohol Syndrome, Fetal Alcohol Effect
Interventions
General information, Baseline brief intervention, Remote online booster sessions, SMS
Other · Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 26, 2026, 4:41 AM EDT
Recruiting Not applicable Interventional

Understanding Pathways to Wellness and Recovery in Detroit - Digital Recovery Support Services

NCT07724275
View directory record Official record
Conditions
Alcohol Use Disorder, Recovery Outcomes, Digital Health
Interventions
Digital recovery support services
Behavioral
Lead sponsor
Brandeis University
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Phase 2 Interventional Results available

Oxytocin to Enhance Alcohol Behavioral Couple Therapy (ABCT)

NCT03846505
View directory record Official record
Conditions
Alcohol Use Disorder, Couples
Interventions
Oxytocin, Placebo
Drug · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 26, 2026, 4:41 AM EDT
Terminated Phase 2 Interventional Results available

Zonisamide for Heavy Drinkers With Bipolar Disorder

NCT01566370
View directory record Official record
Conditions
Alcohol Use Disorders, Bipolar Disorder
Interventions
Zonisamide, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 13, 2017 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Dutasteride Treatment for Reducing Heavy Drinking in AUD: Predictors of Efficacy

NCT04098302
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Dutasteride Capsules, Placebo Capsules
Drug
Lead sponsor
UConn Health
Other
Eligibility
35 Years to 70 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated May 9, 2025 · Synced Oct 26, 2026, 4:41 AM EDT
Not listed Phase 1 Interventional

Interactions Between Cocaine and Ethanol and Disulfiram - 1

NCT00094289
View directory record Official record
Conditions
Alcohol-Related Disorders, Cocaine-Related Disorders
Interventions
Disulfiram
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
2
States / cities
Los Angeles, California • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Phase 4 Interventional Results available

Alcohol Disorder hOsPital Treatment Trial

NCT02478489
View directory record Official record
Conditions
Heavy Drinking, Alcohol Dependence, Alcohol Use Disorder
Interventions
Oral naltrexone (PO-NTX), Extended-release injectable naltrexone (XR-NTX)
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Oct 26, 2026, 4:41 AM EDT
Completed No phase listed Observational

Developing a Music Listening mHealth Intervention for Stress Reduction in Early Recovery

NCT07052318
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Not listed
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Phase 1Phase 2 Interventional

Russia PREVENT (HIV Prevention Partnership in Russian Alcohol Treatment)

NCT00183118
View directory record Official record
Conditions
Alcohol Dependence, Drug Dependence
Interventions
Adapted Enhanced-RESPECT (HIV prevention intervention)
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Oct 26, 2026, 4:41 AM EDT
Completed Phase 2 Interventional

A Placebo-Controlled Trial of Memantine for Alcohol Dependence

NCT00246415
View directory record Official record
Conditions
Alcohol Dependence (Primary Condition), Alcohol Abuse
Interventions
Memantine
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2008 · Synced Oct 26, 2026, 4:41 AM EDT