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ClinicalTrials.gov public records Last synced Oct 28, 2026, 6:19 AM EDT

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Showing 1177–1200 of 1,448 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Alcohol-Related Disorders Clear all
Completed Phase 4 Interventional

Naltrexone Treatment for Alcoholism

NCT00000438
View directory record Official record
Conditions
Alcoholism
Interventions
naltrexone (Revia)
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
30 Years to 55 Years
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2003
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 14, 2010 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of an Evidence-based Stepped Care System for Alcohol and Other Drug Use Problems Among Congolese Refugees in Zambia

NCT05471921
View directory record Official record
Conditions
Alcohol and Substance-Related Mental Disorders
Interventions
SBIRT, Treatment as usual
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
15 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Phase 4 Interventional

Naltrexone Treatment of Alcohol Dependence

NCT00000452
View directory record Official record
Conditions
Alcoholism
Interventions
naltrexone (Revia), Compliance Enhancement Tech., Cognitive Behavior Therapy
Drug · Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 75 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2003
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 28, 2026, 6:19 AM EDT
Terminated Phase 2 Interventional

Ondansetron for the Treatment of Heavy Drinking Among Emerging Adults

NCT00890149
View directory record Official record
Conditions
Alcohol Abuse, Alcoholism
Interventions
Ondansetron, Placebo, BASICS Plus
Drug · Behavioral
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 25 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Columbia, Maryland
Source: ClinicalTrials.gov public record
Updated May 26, 2023 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Not applicable Interventional Results available

Improving Outcomes Among Medical/Surgical Inpatients With Alcohol Use Disorders

NCT03258632
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Drinking Options - Motivate, Shared Decisions, Telemonitor (DO-MoST)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Palo Alto, California • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preliminary Effectiveness of Remotely Monitored Blood Alcohol Concentration Device as Treatment Modality

NCT04380116
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Soberlink
Device
Lead sponsor
Yale University
Other
Eligibility
21 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
North Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 26, 2023 · Synced Oct 28, 2026, 6:19 AM EDT
Active, not recruiting Not applicable Interventional

Chicago Social Drinking Project

NCT00961792
View directory record Official record
Conditions
Alcoholism
Interventions
Ethanol, Placebo, Diphenhydramine, Caffeine
Drug
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 65 Years
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 28, 2026, 6:19 AM EDT
Recruiting Not applicable Interventional

MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

NCT04998916
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Drinking, Substance Use, Drinking, Alcohol, Alcohol Use Disorder (AUD)
Interventions
Real TBS to the mPFC, Sham TBS to the mPFC
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 65 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Phase 2 Interventional

A Study of LY2940094 in Participants With Alcohol Dependency

NCT01798303
View directory record Official record
Conditions
Alcoholism
Interventions
LY2940094, Placebo
Drug
Lead sponsor
BlackThorn Therapeutics, Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
5
States / cities
New Haven, Connecticut • North Miami, Florida • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2017 · Synced Oct 28, 2026, 6:19 AM EDT
Not listed No phase listed Observational

Soberlink Within In-Home Addiction Treatment Program

NCT03902171
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Soberlink
Device
Lead sponsor
In-Home Addiction Treatment Institute, Inc.
Other
Eligibility
21 Years to 75 Years
Enrollment
30 participants
Timeline
2019 – 2020
U.S. locations
2
States / cities
North Haven, Connecticut • Bedford, New Hampshire
Source: ClinicalTrials.gov public record
Updated Apr 5, 2019 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Characterization of [11C]Flumazenil to Image GABA Transmission in Healthy Adult Subjects and Subjects With Alcohol Dependence

NCT01904487
View directory record Official record
Conditions
Alcoholism
Interventions
[11C]flumazenil, Tiagabine
Radiation · Drug
Lead sponsor
Rajesh Narendran
Other
Eligibility
18 Years to 45 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 29, 2017 · Synced Oct 28, 2026, 6:19 AM EDT
Recruiting Not applicable Interventional

Validating an Autonomous Interactive Internet-Based Delivery of an Empirically Supported Cognitive Behavioral Therapy for Comorbidity

NCT05117255
View directory record Official record
Conditions
Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder, Alcohol Use Disorder, Depression
Interventions
Negative Emotions and Addiction Tools Program (NEAT)- Cognitive Behavioral Therapy, Progressive Muscle Relaxation Training (PMRT)
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Endotoxin on Alcohol Consumption

NCT04527185
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Endotoxin
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The Men's Domestic Abuse Check-Up Engages Adult Men Concerned About Their Abusive Behavior and Alcohol or Drug Use

NCT01621334
View directory record Official record
Conditions
Domestic Violence, Substance Abuse
Interventions
Motivational Enhancement Therapy, Educational information
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Male only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 18, 2012 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Community Wise: An Innovative Multi-level Intervention to Reduce Alcohol and Illegal Drug Use

NCT02951455
View directory record Official record
Conditions
Substance Use Disorders
Interventions
Critical Dialogue, Capacity Building Project, Quality of Life Wheel, PF, LC
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years and older · Male only
Enrollment
602 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 23, 2022 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of Alcoholism

NCT00612352
View directory record Official record
Conditions
Alcoholism
Interventions
Ethanol High Dose, Ethanol Low Dose, and Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 30 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Not applicable Interventional

Improving Brief Alcohol Interventions With a Behavioral Economic Supplement

NCT02834949
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Brief Motivational Intervention (BMI), Substance-Free Activity Session (SFAS), Relaxation Session
Behavioral
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 27 Years
Enrollment
393 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Columbia, Missouri • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 28, 2026, 6:19 AM EDT
Recruiting Phase 2 Interventional

Cannabidiol and Alcohol Use Disorder Phenotypes

NCT07279558
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Full-Spectrum Cannabidiol (CBD), Broad-Spectrum Cannabidiol (CBD), Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 28, 2026, 6:19 AM EDT
Withdrawn Phase 2 Interventional

MAP4343 Treatment for Alcohol Use Disorder

NCT04157114
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
MAP4343, Placebo, Standardized behavioral counseling
Drug · Behavioral
Lead sponsor
The Scripps Research Institute
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2022 · Synced Oct 28, 2026, 6:19 AM EDT
Not listed Phase 2 Interventional

Brief Intervention to Reduce Drinking Among Batterers

NCT00539955
View directory record Official record
Conditions
Intimate Partner Violence, Alcohol Use
Interventions
Standard Batterer Intervention, Brief Alcohol Intervention
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
Male only
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2012
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 18, 2012 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Based Prevention of Alcohol and Risky Sex for Older Teens

NCT03521115
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcohol Poison, Alcohol-Related Disorders, Alcohol Impairment, Alcohol Withdrawal, Alcohol Abstinence, Alcohol; Harmful Use, Sex Behavior, Sexual Aggression, Sexual Harassment, Relation, Interpersonal
Interventions
Smart Choices 4 Teens
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
16 Years to 17 Years
Enrollment
411 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Phase 3 Interventional

Combined Pharmacotherapies for Alcoholism

NCT00768508
View directory record Official record
Conditions
Alcoholism
Interventions
Ondansetron 4 ug/kg b.i.d. + Cognitive Behavioral Therapy, Naltrexone 50 mg/day + Cognitive Behavioral Therapy, Ondansetron 4 ug/kg b.i.d.+ Naltrexone 50 mg/day + Cognitive Behavioral Therapy, Placebo + Cognitive Behavioral Therapy
Drug · Other
Lead sponsor
Bankole Johnson
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
2
States / cities
Charlottesville, Virginia • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 15, 2013 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Phase 2 Interventional Results available

Mifepristone Treatment of Alcohol Use Disorder

NCT02179749
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Use Disorders, Alcohol Abuse, Alcoholism
Interventions
Mifepristone 1200 mg daily, Standardized behavioral therapy, Placebo
Drug · Behavioral
Lead sponsor
The Scripps Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Oct 28, 2026, 6:19 AM EDT
Completed Not applicable Interventional Results available

Alcohol, Inflammation, and Mindfulness Study (AIM)

NCT02994043
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Mindfulness-Based Relapse Prevention Therapy, Relapse Prevention Therapy
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 60 Years
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 19, 2023 · Synced Oct 28, 2026, 6:19 AM EDT