Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 1,446 matching trials from the live ClinicalTrials.gov search.
Conditions
Alcohol Use Disorder
Interventions
Intravenous Ethanol, 18F-PF-06445974
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
21 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Post Traumatic Stress Disorder, Alcohol Abuse
Interventions
2mg Buprenex and 380mg Vivitrol, Placebo (SL pill qd, IM injection q4weeks)
Drug
Lead sponsor
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Other
Eligibility
18 Years to 70 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Tuscaloosa, Alabama • West Haven, Connecticut
Completed Phase 1 Interventional Results available

The Women's Recovery Group Study: Stage I Trial

NCT00230100
Conditions
Alcohol-Related Disorders, Substance-Related Disorders
Interventions
The Women's Recovery Group, mixed-gender Group Drug Counseling
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Belmont, Massachusetts
Conditions
Alcohol Use Disorder
Interventions
Low frequency repetitive transcranial magnetic stimulation (rTMS), Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 35 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Recruiting Not applicable Interventional Accepts healthy volunteers

Primary Connections for Youth and Families

NCT05964010
Conditions
Substance Use
Interventions
Standard Screening, Standard Psychoeducation, Standard Brief Negotiated Interview (BNI), Standard Referral to Treatment (RT), Family Screening, Family Psychoeducation, Family Brief Negotiated Interview (BNI), Family Facilitated Conversation (FC) & Referral to Treatment (RT)
Behavioral
Lead sponsor
The National Center on Addiction and Substance Abuse at Columbia University
Other
Eligibility
12 Years to 17 Years
Enrollment
2,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
New York, New York
Conditions
Alcohol Dependence
Interventions
VIVITROL 380 mg, Placebo
Drug
Lead sponsor
Alkermes, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Belmont, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acute Alcohol Response In Bipolar Disorder: a fMRI Study

NCT04063384
Conditions
Bipolar Disorder, Alcohol Drinking, Alcohol Use Disorder
Interventions
alcohol beverage, Placebo beverage
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
21 Years to 26 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Austin, Texas
Conditions
Alcohol Use Disorder, Post Traumatic Stress Disorder
Interventions
Computerized Plasticity-Based Adaptive Cognitive Training
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Alcohol Dependence, Depression
Interventions
Mecamylamine, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Alcohol Use Disorder (AUD), Transcranial Magnetic Stimilation
Interventions
Deep Transcranial Magnetic Stimulation (dTMS) H7 coil - Active, Deep Transcranial Magnetic Stimulation (dTMS) H7 coil - Sham
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Bipolar Disorder, Alcoholism, Alcohol Dependence
Interventions
Topiramate
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
Palo Alto, California
Recruiting Not applicable Interventional Accepts healthy volunteers

Adaptation of the Family Check-Up Online

NCT07025083
Conditions
Substance Use (Drugs, Alcohol)
Interventions
Adapted Family Check-Up Online, Original Family Check-Up Online
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
11 Years to 14 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Eugene, Oregon
Conditions
Substance Use, Stress, Relation, Interpersonal, Bullying, Victimisation, Mental Health Issue, Sleep, Inadequate, Social Skills
Interventions
PeerLearning.net
Behavioral
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
Not listed
Enrollment
924 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Eugene, Oregon
Conditions
Alcohol Use Disorder
Interventions
Intravenous Alcohol
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 65 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Alcohol Use Disorder
Interventions
Zonisamide, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 70 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
West Haven, Connecticut
Conditions
Alcohol Use Disorder
Interventions
Mazdutide, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
21 Years to 65 Years
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
25
States / cities
Scottsdale, Arizona • Rogers, Arkansas • Fountain Valley, California + 20 more
Conditions
Cirrhosis, Cirrhosis, Liver, Cirrhosis Early, Cirrhosis Due to Hepatitis B, Cirrhosis Advanced, Cirrhosis Infectious, Cirrhosis Alcoholic, Cirrhosis Due to Hepatitis C
Interventions
Rosuvastatin
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 75 Years
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
13
States / cities
La Jolla, California • Los Angeles, California • San Francisco, California + 7 more
Conditions
Tobacco Use Disorder
Interventions
Standard treatment plus brief alcohol intervention, Standard treatment (ST)
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years to 95 Years
Enrollment
236 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Accepts healthy volunteers

Understanding Genetic Risk for Alcohol Use Disorder

NCT05143073
Conditions
Alcohol Use Disorder
Interventions
Alcohol use disorder and strategies to reduce risk educational material, Complex polygenic risk scores, alcohol use disorder, and strategies to reduce risk educational material
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Richmond, Virginia
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Fetal Alcohol Syndrome/ARND Research Consortion

NCT00164554
Conditions
Fetal Alcohol Syndrome
Interventions
Parent-child Interaction Therapy (PCIT)
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
3 Years to 7 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Conditions
Alcohol Dependence
Interventions
Computerized Alcohol Screening, Brief Negotiated Interview
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
840 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Bridgeport, Connecticut
Conditions
Attention Deficit Hyperactivity Disorder, Alcohol-Related Disorders, Substance-Related Disorders
Interventions
SUCCEEDS Program, Living a Healthy College Lifestyle
Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 24 Years
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
College Park, Maryland
Conditions
Liver Diseases, Alcoholic
Interventions
A-CHESS
Device
Lead sponsor
New York Presbyterian Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Completed Phase 1 Interventional Results available

W-SUDs for COVID-19

NCT04460027
Conditions
Substance Use Disorders, Alcohol Use Disorder
Interventions
Woebot Substance Use Disorder
Other
Lead sponsor
Woebot Health
Industry
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Palo Alto, California