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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Alcohol-related Disorders Clear all
Terminated Phase 2 Interventional Results available

Kappa Opioid Receptor Antagonism for the Tx of AUD and Comorbid PTSD

NCT03852628
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Alcohol Abuse
Interventions
2mg Buprenex and 380mg Vivitrol, Placebo (SL pill qd, IM injection q4weeks)
Drug
Lead sponsor
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
Other
Eligibility
18 Years to 70 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Tuscaloosa, Alabama • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Not applicable Interventional Results available

Brief Therapy Intervention for Heavy/Hazardous Drinking in HIV-Positive Women

NCT00127231
View directory record Official record
Conditions
HIV Infections, Alcoholism
Interventions
Brief alcohol intervention based on Project Treat, Standard care
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
Female only
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 5, 2017 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 2 Interventional Results available

Double-blind Pilot Trial of Mirtazapine for the Treatment of Co-occurring AD/MDD.

NCT02185131
View directory record Official record
Conditions
Major Depressive Disorder, Alcohol Use Disorder
Interventions
Mirtazapine, Placebo
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Michigan SPARC Trial

NCT04861792
View directory record Official record
Conditions
Alcohol, Drinking, Alcohol Use Disorder (AUD)
Interventions
Michigan SPARC Quality Improvement Intervention
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
9,590 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 26, 2023 · Synced Jun 10, 2026, 6:18 AM EDT
Recruiting No phase listed Observational

Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMC

NCT06864819
View directory record Official record
Conditions
Postoperative Complications, Alcohol Use Disorder
Interventions
Blood Draw
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
21 Years to 79 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Personalized Drinking Feedback Interventions

NCT01211353
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Personalized Drinking Feedback, Education-Only
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 80 Years
Enrollment
325 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 15, 2017 · Synced Jun 10, 2026, 6:18 AM EDT
Recruiting No phase listed Observational

Effect of Alcohol and Drugs of Abuse on Immune Function in Critically Ill Patients With Respiratory Failure

NCT02299921
View directory record Official record
Conditions
Infection, Alcohol Abuse, Drugs of Abuse, Lung Injury
Interventions
Characterize alcohol and drug use
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 90 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2029
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Not applicable Interventional

Motivational Interviews for Incarcerated Teens - 1

NCT00227916
View directory record Official record
Conditions
Alcoholic Intoxication, Marijuana Abuse
Interventions
Behavior Therapy
Behavioral
Lead sponsor
Brown University
Other
Eligibility
14 Years to 19 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 24, 2014 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Not applicable Interventional

fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults

NCT01320748
View directory record Official record
Conditions
Substance Abuse, Substance Dependence, Alcohol Abuse, Drug Use, Relapse
Interventions
Dual Processing, Relapse Prevention
Behavioral
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 29, 2018 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 4 Interventional Results available

Sertraline Pharmacotherapy for Alcoholism Subtypes

NCT00368550
View directory record Official record
Conditions
Alcoholism
Interventions
Sertraline, Placebo
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 65 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 20, 2011 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Not applicable Interventional Results available

Automated Reinforcement Management System (ARMS)

NCT04656925
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Contingency management
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 1 Interventional

Clinical Trial to Evaluate the Safety of PT150 (Formerly ORG34517) When it is Taken Concurrently With Alcohol

NCT03548714
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Interaction
Interventions
PT150, Beverage
Drug · Other
Lead sponsor
Pop Test Oncology LLC
Industry
Eligibility
21 Years to 64 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2019 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Not applicable Interventional

ARCH Research Protocol for Provider Alcohol Pharmacotherapy Training and Assessment

NCT02610517
View directory record Official record
Conditions
HIV, Alcoholism
Interventions
Provider Training, Patient Intervention
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
3
States / cities
Birmingham, Alabama • Baltimore, Maryland • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 2, 2024 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 1Phase 2 Interventional

Open Label Trial of Acamprosate in Bipolar Alcoholics

NCT00330486
View directory record Official record
Conditions
Alcohol Dependence, Bipolar Disorder
Interventions
Acamprosate
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 18, 2008 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Cannabidiol in Youth Alcohol Use Disorder

NCT05317546
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Cannabidiol
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
16 Years to 22 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Pitt Center for Emergency Responder Wellness

NCT05357586
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression, Anxiety, Alcohol Use Disorder
Interventions
Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 3 Interventional Results available

A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin

NCT01143246
View directory record Official record
Conditions
Hepatorenal Syndrome
Interventions
Terlipressin, Placebo
Drug
Lead sponsor
Mallinckrodt
Industry
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
71
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 51 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2022 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 2 Interventional Results available

Sweet Preference and Alcohol Craving

NCT01296646
View directory record Official record
Conditions
Alcohol Dependence, Alcohol Abuse
Interventions
Naltrexone, Brenda Therapy Sessions, Placebo
Drug · Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 24, 2013 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 2 Interventional Results available

Oxytocin Suppresses Substance Use Disorders Associated With Chronic Stress

NCT02742532
View directory record Official record
Conditions
Alcohol Use Disorder, Stress Disorders, Post-Traumatic, Anxiety Disorders, Substance Use Disorders
Interventions
Oxytocin, Placebo
Drug
Lead sponsor
Jennifer Mitchell
Other
Eligibility
18 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 2 Interventional

Maximizing the Efficacy of Cognitive Behavior Therapy and Contingency Management

NCT00350649
View directory record Official record
Conditions
Marijuana Dependence
Interventions
Standard CBT, CBT+CM/adherence, CM/abstinence, CM/abstinence+CBT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 26, 2011 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Not applicable Interventional Results available

Telephone Disease Management At-Risk Drinking (TDM II)

NCT00123409
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Telephone disease management, Usual Care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 3 Interventional

COMBINE (Acamprosate/Naltrexone)

NCT00006206
View directory record Official record
Conditions
Alcoholism
Interventions
naltrexone (Revia), acamprosate (Campral)
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
1,375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2006
U.S. locations
12
States / cities
New Haven, Connecticut • Miami, Florida • Belmont, Massachusetts + 8 more
Source: ClinicalTrials.gov public record
Updated May 2, 2010 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 4 Interventional

Naltrexone Treatment of Alcohol Dependence

NCT00000452
View directory record Official record
Conditions
Alcoholism
Interventions
naltrexone (Revia), Compliance Enhancement Tech., Cognitive Behavior Therapy
Drug · Behavioral
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
18 Years to 75 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2003
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jun 10, 2026, 6:18 AM EDT
Completed Phase 3 Interventional Results available

Pharmacogenetic Treatment With Anti-Glutaminergic Agents for Comorbid PTSD & AUD

NCT02884908
View directory record Official record
Conditions
PTSD, Alcohol Use Disorder
Interventions
Pregabalin plus BBCET, Placebo plus BBCET
Drug · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Jun 10, 2026, 6:18 AM EDT