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ClinicalTrials.gov public records Last synced Sep 30, 2026, 6:51 PM EDT

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Showing 25–48 of 108 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: American Indian or Alaska Native Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Qoyangnuptu: Qoyangnuptu Intervention (QI) App

NCT06254924
View directory record Official record
Conditions
Mental Health Wellness 1
Interventions
QI App Users, Parents/Guardians of QI App Users
Behavioral
Lead sponsor
Northern Arizona University
Other
Eligibility
14 Years to 25 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Flagstaff, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 23, 2025 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Not applicable Interventional Results available

We Are Here Now: a Multi-level, Multicomponent Sexual and Reproductive Health Intervention for American Indian Youth

NCT03694418
View directory record Official record
Conditions
Reproductive Behavior, Sexual Behavior
Interventions
We are here now: a multi-level, multi-component sexual and reproductive health intervention for American Indian youth
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
14 Years to 18 Years
Enrollment
453 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Bozeman, Montana • Poplar, Montana
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Sep 30, 2026, 6:51 PM EDT
Active, not recruiting Not applicable Interventional

Counseling for Harm Reduction and Retention in Medication-assisted Treatment - Cherokee Nation

NCT05733442
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Treatment as usual (TAU), CHaRRM-CN
Other
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Tahlequah, Oklahoma • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 30, 2026, 6:51 PM EDT
Completed No phase listed Observational

American Indian and Alaska Native Head Start Family and Child Experiences Survey

NCT03842111
View directory record Official record
Conditions
Head Start Participation
Interventions
Not listed
Lead sponsor
Mathematica Policy Research, Inc.
Other
Eligibility
3 Years and older
Enrollment
1,194 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Culturally Grounded Early Substance Use Prevention for American Indian Families

NCT02383225
View directory record Official record
Conditions
Substance Use
Interventions
Lakota Language enhancement, Facebook Supplement, Substance Use Resistance Skills
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 85 Years
Enrollment
449 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 20, 2020 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Not applicable Interventional Results available

Community Trial in the Cherokee Nation

NCT04839978
View directory record Official record
Conditions
Opioid Abuse
Interventions
Connect Program, Communities Mobilizing for Change and Action (CMCA)
Behavioral
Lead sponsor
Emory University
Other
Eligibility
15 Years to 17 Years
Enrollment
919 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Tahlequah, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alzheimer's Disease and Precision Medicine Research Among Native People

NCT03448601
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Culturally tailored brochure intervention group, Culturally tailored video intervention group
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years to 100 Years
Enrollment
523 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Rapid City, South Dakota
Source: ClinicalTrials.gov public record
Updated Jun 27, 2024 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Strategies: Motivational Interviewing/Psychoeducation

NCT03458299
View directory record Official record
Conditions
Alcohol Use, Underage, Substance Use, Underage Drinking
Interventions
Motivational Interviewing, Psychoeducation
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
13 Years to 20 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Valley Center, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2022 · Synced Sep 30, 2026, 6:51 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Happy Teeth for Hopi Tots: Cultural Adaptation of an Oral Health Entertainment-Education Intervention

NCT05297526
View directory record Official record
Conditions
Early Childhood Caries
Interventions
Culturally adapted children's book, Standard informational brochure on children's oral health
Behavioral
Lead sponsor
Northern Arizona University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Flagstaff, Arizona
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Healthy Children, Strong Families: American Indian Communities Preventing Obesity

NCT01776255
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Healthy Children, Strong Families, Child Safety
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
2 Years to 5 Years
Enrollment
900 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
5
States / cities
White Earth, Minnesota • Browning, Montana • Albuquerque, New Mexico + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Sep 30, 2026, 6:51 PM EDT
Recruiting No phase listed Observational

Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study

NCT07214610
View directory record Official record
Conditions
Breast Cancer, Breast Neoplasms
Interventions
Structured behavioral intervention
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
20 Years to 74 Years · Female only
Enrollment
3,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2044
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Health Effects of Traditional Indigenous Chokeberry

NCT05410327
View directory record Official record
Conditions
Inflammation, Mental Health Wellness 1, Oxidative Stress
Interventions
Chokeberry (Aronia melanocarpa) juice
Other
Lead sponsor
University of North Dakota
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated May 1, 2023 · Synced Sep 30, 2026, 6:51 PM EDT
Completed No phase listed Observational Results available

Evaluating the Navajo Community Outreach and Patient Empowerment (COPE) Program

NCT03326206
View directory record Official record
Conditions
Diabetes Mellitus, Metabolic Syndrome, Hypertension, Chronic Disease
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
28,813 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
6
States / cities
Chinle, Arizona • Fort Defiance, Arizona • Kayenta, Arizona + 3 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Not applicable Interventional

Motivational Incentives for Alcohol Abstinence in American Indian and Native Alaskan Adults

NCT02174315
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Contingency Management
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Pullman, Washington
Source: ClinicalTrials.gov public record
Updated May 1, 2023 · Synced Sep 30, 2026, 6:51 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Diabetes Nutrition Education for American Indian and Alaska Native Communities

NCT04254653
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
American Indian and Alaska Native What Can I Eat?
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
3
States / cities
Lakeport, California • Cherokee, North Carolina • Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Sep 30, 2026, 6:51 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Strong Heart Water Study

NCT03725592
View directory record Official record
Conditions
Arsenic Poisoning
Interventions
Standard Treatment, Intensive Education
Other · Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
10 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Culturally Tailoring an Advance Care Planning Intervention for American Indians

NCT05304117
View directory record Official record
Conditions
Advance Care Planning
Interventions
Advance Care Planning
Behavioral
Lead sponsor
Western Carolina University
Other
Eligibility
18 Years and older
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Asheville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Sep 30, 2026, 6:51 PM EDT
Recruiting Not applicable Interventional

A Nutrition & Exercise Prehabilitation Intervention on Inflammatory Biomarkers in AI Cancer Patients

NCT06644560
View directory record Official record
Conditions
Cancer
Interventions
Prehabilitation Intervention
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nxstan: A Culturally Tailored Intervention to Prevent Diabetes in American Indian Men

NCT02952352
View directory record Official record
Conditions
Diabetes
Interventions
Diabetes Prevention Program
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
21 Years to 65 Years · Male only
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Nespelem, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 30, 2026, 6:51 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

It's Native: Nudging Healthy Ways

NCT05470296
View directory record Official record
Conditions
Diet, Healthy, Physical Activity
Interventions
Move & Eat 2 Live
Behavioral
Lead sponsor
University of Southern Mississippi
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated Nov 13, 2024 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Immunogenicity of H. Influenzae Type b PRP-OMP Vaccines in American Indian and Alaska Native Children (the HibVax Study)

NCT04978818
View directory record Official record
Conditions
Haemophilus Influenzae Type B Infection
Interventions
Vaxelis, PedvaxHIB
Drug
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
6 Weeks to 12 Weeks
Enrollment
333 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
5
States / cities
Anchorage, Alaska • Chinle, Arizona • Fort Defiance, Arizona + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2024 · Synced Sep 30, 2026, 6:51 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predicting Insulin Resistance in American Indian Youth

NCT00498030
View directory record Official record
Conditions
Insulin Resistance, Stress, Psychological
Interventions
Not listed
Lead sponsor
University of Nebraska
Other
Eligibility
5 Years to 18 Years
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2018
U.S. locations
1
States / cities
Rosebud, South Dakota
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Sep 30, 2026, 6:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents

NCT02904629
View directory record Official record
Conditions
Sex, Unprotected Sex, Contraception, Alcohol Use, Drug Use, Pregnancy
Interventions
Respecting the Circle of Life (RCL), Control Program
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
11 Years and older
Enrollment
1,072 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 19, 2022 · Synced Sep 30, 2026, 6:51 PM EDT
Active, not recruiting No phase listed Observational

Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population

NCT05863052
View directory record Official record
Conditions
Immune Checkpoint Inhibitors, Metastatic Solid Tumor, Nonsmall Cell Lung Cancer, Melanoma, Renal Cell Carcinoma, Gastrointestinal Cancer, Squamous Cell Carcinoma
Interventions
Immunotherapy
Biological
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 99 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
6
States / cities
Tucson, Arizona • Albuquerque, New Mexico • Oklahoma City, Oklahoma + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Sep 30, 2026, 6:51 PM EDT