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ClinicalTrials.gov public records Last synced May 21, 2026, 11:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Amputation; Traumatic, Leg, Lower Clear all
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Amputation, Amputation, Traumatic, Amputation; Traumatic, Leg, Lower
Interventions
Compliant Adaptive Energy Storage and Return Foot, AllPro
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 26, 2024 · Synced May 21, 2026, 11:08 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Not listed
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
10
States / cities
San Francisco, California • Tampa, Florida • Baltimore, Maryland + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2021 · Synced May 21, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Amputation, Surgical, Amputation, Traumatic, Phantom Limb Pain, Phantom Pain Following Amputation of Lower Limb
Interventions
ACTIVE cryoneurolysis, SHAM cryoneurolysis
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced May 21, 2026, 11:08 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Elevated Metabolic Cost
Interventions
Gait Training
Other
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 45 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2007
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 20, 2010 · Synced May 21, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Amputation, Amputation; Traumatic, Leg, Lower
Interventions
Laminated Socket, Quatro, Infinite Socket, CJ Socket
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced May 21, 2026, 11:08 PM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
ArtAssist© Device
Device
Lead sponsor
Temple University
Other
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 7, 2016 · Synced May 21, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Amputation, Traumatic, Traumatic Amputation of Lower Extremity, Wounds and Injuries
Interventions
Otto Bock prosthesis, Ossur prosthesis, Freedom Innovations prosthesis
Device
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced May 21, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Amputation, Prosthesis User, Amputation; Traumatic, Leg: Thigh, Between Hip and Knee, Limb; Absence, Congenital, Lower, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Above Knee
Interventions
Ottobock C-Leg 4 Microprocessor Knee, Ottobock Kenevo
Device
Lead sponsor
Hanger Institute for Clinical Research and Education, LLC
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced May 21, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Above Knee (Injury), Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
Interventions
Power Knee
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Holliston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced May 21, 2026, 11:08 PM EDT
Enrolling by invitation No phase listed Observational
View directory record Official record
Conditions
Lower Extremity Amputation, Trans-Tibial Amputation, Traumatic Lower Extremity Amputation, Agonist-Antagonist Myoneural Interface
Interventions
Modified Amputation, Standard Amputation
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced May 21, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Amputation; Traumatic, Leg, Lower
Interventions
Phase 2 Prescribed Prosthesis, Phase 2 Robotic Prosthetic Leg, Phase 3 No Prosthesis, Phase 3 Robotic Prosthetic Leg, Phase 3 Prescribed Prosthesis
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2022 · Synced May 21, 2026, 11:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Powered ankle-foot prosthesis
Device
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced May 21, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity
Interventions
FES
Device
Lead sponsor
Alicia Koontz
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 1, 2024 · Synced May 21, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Transtibial Amputation, Peripheral Artery Disease, Diabetes Mellitus
Interventions
Error-augmentation gait training, Error-correction gait training, Supervised walking
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 89 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Aurora, Colorado • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced May 21, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Above Knee (Injury), Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
Interventions
Ossur Power Knee, Reboocon Intuy Knee
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced May 21, 2026, 11:08 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Interventions
Spinal cord stimulator
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced May 21, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Ischemic Preconditioning
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced May 21, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Amputation; Traumatic, Leg, Lower
Interventions
OPRA
Device
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
22 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Bethesda, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced May 21, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Powered ankle-foot prosthesis, No device
Device · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 24, 2014 · Synced May 21, 2026, 11:08 PM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Amputation, Amputation of Lower Limb, Amputation of Upper Limb, Amputation, Limb Loss, Amputation, Traumatic/Surgery, Cryo Analgesia
Interventions
cryoablation
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2035
U.S. locations
4
States / cities
Pittsfield, Massachusetts • Manchester, New Hampshire • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced May 21, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity
Interventions
Specialized Functional Prosthetic Training
Other
Lead sponsor
Miami VA Healthcare System
Federal
Eligibility
40 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 24, 2011 · Synced May 21, 2026, 11:08 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Amputation; Traumatic, Leg, Lower
Interventions
Tap dance program
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced May 21, 2026, 11:08 PM EDT
Terminated Not applicable Interventional Results available
View directory record Official record
Conditions
Traumatic Amputation of Lower Extremity, Phantom Limb Pain
Interventions
Spinal cord stimulator
Device
Lead sponsor
Lee Fisher, PhD
Other
Eligibility
22 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced May 21, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Amputation, Amputation; Traumatic, Leg, Lower, Amputation Stump, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Below Knee (Injury)
Interventions
ICE Condition, Sham Condition
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Holliston, Massachusetts • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced May 21, 2026, 11:08 PM EDT