- Conditions
- Peripheral Arterial Disease, Peripheral Vascular Disease, Amputation, Lower Limb Amputation Knee, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
- Interventions
- Ischemic Conditioning Low - Sham Comparator, Ischemic Conditioning High - Active Comparator
- Procedure
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
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Showing 1–24
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Phantom Limb Pain
- Interventions
- Distractor and Lower limb VR
- Device
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Foot Ulcer, Diabetic
- Interventions
- NEOX® CORD 1K, Standard of Care (Pressure Bandage)
- Other · Procedure
- Lead sponsor
- Amniox Medical, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 3
- States / cities
- Tucson, Arizona • Castro Valley, California • Newnan, Georgia
- Conditions
- Lower Limb Amputation
- Interventions
- Conventional Prosthetic Transfemoral Socket System, Novel Prosthetic transfemoral socket system
- Device
- Lead sponsor
- Ohio Willow Wood
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 8 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2014
- U.S. locations
- 2
- States / cities
- Columbus, Ohio • Mount Sterling, Ohio
- Conditions
- Amputation Wound, Traumatic Amputation of Toe, Dysvascular Amputation of Lower Limb
- Interventions
- Not listed
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 27 Years to 89 Years · Male only
- Enrollment
- 4,549 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2016
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Above Knee (Injury)
- Interventions
- Questionnaire
- Other
- Lead sponsor
- Minneapolis Veterans Affairs Medical Center
- Federal
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Lower-Limb Amputation
- Interventions
- Powered and passive lower limb prosthesis and control
- Device
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2032
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Neuroma, Neuroma Amputation, Neuroma of Upper Limb, Neuroma of Lower Limb
- Interventions
- Indocyanine green
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Amputation; Lower Extremity, Pain, Persistent Postsurgical
- Interventions
- Surgical Implantation
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Diabetes Mellitus, Critical Limb Ischemia, Lower Limb Amputation Knee, Peripheral Arterial Disease
- Interventions
- Active Arm N-acetyl cysteine (NAC), Placebo Arm
- Drug
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 30 Years to 90 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Extremity Lower Wounds
- Interventions
- SPY Intra-operative Angiography
- Combination Product
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Traumatic Amputation of Lower Extremity
- Interventions
- Not listed
- Lead sponsor
- Major Extremity Trauma Research Consortium
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2021
- U.S. locations
- 10
- States / cities
- San Francisco, California • Tampa, Florida • Baltimore, Maryland + 7 more
- Conditions
- Lower Limb Amputation
- Interventions
- Active vacuum test prosthesis
- Device
- Lead sponsor
- Indiana University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Transfemoral Amputation, Unilateral Traumatic Amputation of Leg at or Above Knee
- Interventions
- C leg compared to subject's mechanical leg (Otto Bock)
- Device
- Lead sponsor
- Shirley Ryan AbilityLab
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2019
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Phantom Limb Pain
- Interventions
- Lower extremity amputation
- Procedure
- Lead sponsor
- North Texas Veterans Healthcare System
- Federal
- Eligibility
- 18 Years and older
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Amputation, Physical Activity
- Interventions
- Weekly exercise sessions with physical therapist and psychologist, Home-based exercises
- Behavioral
- Lead sponsor
- Rosalind Franklin University of Medicine and Science
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 2
- States / cities
- North Chicago, Illinois
- Conditions
- Severe Distal Tibia Injury, Severe Ankle Injury, Severe Foot Injury, Major Soft Tissue Loss, Major Bone Articular Surface Loss, Major Ankle Articular Surface Loss
- Interventions
- Not listed
- Lead sponsor
- Major Extremity Trauma Research Consortium
- Other
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 664 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2019
- U.S. locations
- 33
- States / cities
- Birmingham, Alabama • San Diego, California • San Francisco, California + 26 more
- Conditions
- Lower Extremity Amputation, Trans-Tibial Amputation, Traumatic Lower Extremity Amputation, Agonist-Antagonist Myoneural Interface
- Interventions
- Modified Amputation, Standard Amputation
- Procedure
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Diabetic Foot Ulcer
- Interventions
- Not listed
- Lead sponsor
- Boise VA Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- Boise, Idaho
- Conditions
- Transtibial Amputation
- Interventions
- Virtual Reality Gait Training, Treadmill Gait Training
- Other
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Amputation; Traumatic, Leg, Lower
- Interventions
- Tap dance program
- Other
- Lead sponsor
- University of Nevada, Las Vegas
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Las Vegas, Nevada
- Conditions
- Amputation
- Interventions
- Balance and fall recovery training
- Behavioral
- Lead sponsor
- University of Nevada, Las Vegas
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Las Vegas, Nevada
- Conditions
- Acute Pain Management, Analgesic, Nonopioid, Amputation of Lower Extremity, All Causes
- Interventions
- Oral Ketamine
- Drug
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2021
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Amputation
- Interventions
- Fillauer Slope Adaptive Foot, Fillauer Motion Foot SLX
- Device
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota