Search | Clinical Trials Finder

Conditions: Amputation
Interventions: Not listed
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 1,572 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2016
U.S. locations: 2
States / cities: Miami, Florida • Seattle, Washington

Conditions: Amputation of Lower Limb
Interventions: Prosthetic foot, Physical therapy; Other
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Amputation of Lower Limb Above Knee, Amputee, Amputation
Interventions: Bio Leg; Device
Lead sponsor: University of Florida; Other
Eligibility: 40 Years to 70 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Ambulation With the "Take Home" or Passive Prosthesis, Ambulation With the Motorized Prosthesis in the "Off" Configuration, Ambulation With the Motorized Prosthesis in the "Transparent" Condition, Ambulation With the Motorized Prosthesis in the "Powered" Condition
Interventions: Passive prosthesis, Motorized prosthesis; Device
Lead sponsor: Northern Arizona University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Flagstaff, Arizona

Conditions: Lower Limb Amputation
Interventions: Comprehensive assessment of walking patterns and functional mobility, Comprehensive assessment of eye movements during walking, Questionnaire Assessments completed; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Lower Extremity Amputation
Interventions: Torsionally adaptive prosthesis with 0:1 coupling ratio, Torsionally adaptive prosthesis with 1:6 coupling ratio, Torsionally adaptive prosthesis with 1:4 coupling ratio, Torsionally adaptive prosthesis with 1:3 coupling ratio, Torsionally adaptive prosthesis with 1:2 coupling ratio; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Amputation, Diabetes Complications
Interventions: Custom prosthetic socket with mechanical vibrators (stochastic resonance), Conventional prosthetic socket (current clinical practice); Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 70 Years
Enrollment: 17 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2018
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Lower Limb Amputation Below Knee (Injury)
Interventions: Apply ENABLE sensing pad, Insert small pads at pressure tolerant locations; Device
Lead sponsor: North Carolina State University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Raleigh, North Carolina

Conditions: Amputation
Interventions: Unrectified prosthetic socket, Rectified prosthetic socket; Device
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2005
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Amputation
Interventions: Clinical Descriptive Measures related to amputation collected, GPS device education/distributed, activPAL device education/distributed, Questionnaire Assessments completed; Other
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Lower-Limb Amputation
Interventions: Exercise self-management, Attention control; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 40 Years to 89 Years
Enrollment: 95 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Diabetes Mellitus, Critical Limb Ischemia, Lower Limb Amputation Knee, Peripheral Arterial Disease
Interventions: Active Arm N-acetyl cysteine (NAC), Placebo Arm; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 30 Years to 90 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Lower Limb Amputation Below Knee (Injury)
Interventions: Not listed
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Diabetic Foot Ulcer Outcome, Quality of Patient Care
Interventions: cellular and tissue based therapy, negative pressure wound therapy, debridement, advanced wound therapy, Nutritional screening, off-loading, Hyperbaric oxygen Therapy; Biological · Device · Procedure + 1 more
Lead sponsor: U.S. Wound Registry; Other
Eligibility: Not listed
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: The Woodlands, Texas

Conditions: Amputation, Prosthesis User, Amputation; Traumatic, Leg: Thigh, Between Hip and Knee, Limb; Absence, Congenital, Lower, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Above Knee
Interventions: Ottobock C-Leg 4 Microprocessor Knee, Ottobock Kenevo; Device
Lead sponsor: Hanger Institute for Clinical Research and Education, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Amputation; Traumatic, Leg, Lower
Interventions: Tap dance program; Other
Lead sponsor: University of Nevada, Las Vegas; Other
Eligibility: 18 Years and older
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Amputation
Interventions: Not listed
Lead sponsor: Össur Iceland ehf; Industry
Eligibility: 18 Years and older
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2033
U.S. locations: 1
States / cities: Irvine, California

Conditions: Amputation
Interventions: massage; Other
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Lower Limb Amputation Below Knee (Injury), Diurnal Residual Limb Fluid Volume Fluctuation
Interventions: Auto Adjusting Prosthesis; Device
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Above Knee (Injury)
Interventions: Questionnaire; Other
Lead sponsor: Minneapolis Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2023
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Diabetic Foot Ulcer
Interventions: Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic; Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Amputation
Interventions: Not listed
Lead sponsor: University of South Florida; Other
Eligibility: 21 Years to 65 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Infections, Infected Wound, Nonunion of Fracture, Injury Leg, Amputation, Internal Fixation; Complications, Infection or Inflammation, Fracture, Lower Extremity Fracture, Antibiotic Side Effect
Interventions: Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics; Drug
Lead sponsor: Major Extremity Trauma Research Consortium; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 13
States / cities: Indianapolis, Indiana • Baltimore, Maryland • Minneapolis, Minnesota + 9 more

Conditions: Amputation, Anesthesia, Local, Opioid Use
Interventions: Liposomal bupivacaine; Drug
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years and older
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Loma Linda, California

Search by objective public record fields.

A Client-Based Outcome System for Individuals With Lower Limb Amputation

Personalized Prosthetic Foot Prescription and Rehabilitation for Veterans With Lower Limb Loss

Bio Leg: Advancing Mobility (BAM)

Investigation of Motorized Lower-limb Prostheses

The Role of Visual Attention and Environmental Complexity in Real-world Mobility for People With Lower Limb Amputation

Pivot-Flex Foot: Optimal Coupling Ratio Between Transverse and Sagittal-plane Motions Using a Torsionally Adaptive Prosthesis for Individuals With Lower Limb Amputation

Use of Subtle Vibration to Improve Walking Ability by Lower Limb Amputees

R21: An Easy-to-use, iNtelligent, Affordable LinEr (ENABLE) System for Socket Fit Assessment

Prosthetic Limbs After Leg Amputation: Alternative Method of Socket Design

Assessing Ambulatory and Non-ambulatory Community Mobility in People With Lower Limb Amputation

Walking Exercise Sustainability Through Telehealth for Veterans With Lower-limb Amputation

N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes

Influence of Socket Volume on Prosthesis Performance

The Diabetic Foot Ulcer Registry

Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators

Tap Dance for Adults With Lower Limb Amputation

Pro APP Prosthetic Outcome Registry

Massage on Pain Levels, Range of Motion, and Muscle Strength in Unilateral Lower Limb Amputees

An Automatically Adjusting Prosthetic Socket for People With Transtibial Amputation

Women's-Specific Footwear With Prosthetic Feet

Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot Ulceration Or Subsequent Amputation in Patients With a History of a Diabetic Foot Ulceration

Comparison of Prosthetic Knee Performance During Sitting and Standing

PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation

Use of Long-acting Bupivacaine In Lower Extremity Amputation