Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jun 10, 2026, 10:17 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Amputations Clear all
Recruiting Not applicable Interventional

Surgical Treatments for Postamputation Pain

NCT05009394
View directory record Official record
Conditions
Residual Limb Pain, Amputation Neuroma, Phantom Limb Pain, Pain, Neuropathic, Pain, Nerve
Interventions
Targeted Muscle Reinnervation (TMR), Regenerative Peripheral Nerve Interface (RPNI), Standard neuroma treatment, neuroma excision, and muscle burying
Procedure
Lead sponsor
Prometei Pain Rehabilitation Center
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
3
States / cities
Chicago, Illinois • Boston, Massachusetts • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

Functional Outcomes in Dysvascular Transfemoral Amputees

NCT01537211
View directory record Official record
Conditions
Transfemoral Amputation, Unilateral Traumatic Amputation of Leg at or Above Knee
Interventions
C leg compared to subject's mechanical leg (Otto Bock)
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 5, 2019 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional

A Test-Drive Strategy for the Prescription of Prosthetic Feet for People With Leg Amputations

NCT03651830
View directory record Official record
Conditions
Amputation
Interventions
Prosthetic Foot Emulator, Commercially available prosthetic feet
Device
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years to 89 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
3
States / cities
Minneapolis, Minnesota • San Antonio, Texas • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Jun 10, 2026, 10:17 PM EDT
Completed No phase listed Observational

Study of Medial-Lateral Center of Pressure Displacement in Unilateral Transfemoral Amputees

NCT02299674
View directory record Official record
Conditions
Unilateral Transfemoral Amputation
Interventions
Level overground ambulation
Other
Lead sponsor
Southern California Institute for Research and Education
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reduction of Shear Forces Using Semi-flexible Sockets on Transtibial Amputees

NCT03390153
View directory record Official record
Conditions
Amputation
Interventions
semi flexible socket, rigid fiber socket
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Jun 10, 2026, 10:17 PM EDT
Terminated Phase 4 Interventional Results available

Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain

NCT05046639
View directory record Official record
Conditions
Pain, Amputation
Interventions
10 mL 2% lidocaine, 10 mL preservative free saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 2, 2025 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Virtual Reality Prosthetic Training and Rehabilitation

NCT02666859
View directory record Official record
Conditions
Amputation of Upper Limb
Interventions
Virtual Reality
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 11, 2019 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

Intent Recognition for Prosthesis Control

NCT05537792
View directory record Official record
Conditions
Amputation
Interventions
Robotic Knee/Ankle Prosthesis
Device
Lead sponsor
Georgia Institute of Technology
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Jun 10, 2026, 10:17 PM EDT
Withdrawn Not applicable Interventional

An Uneven Terrain Surface to Improve Locomotor Robustness in People With Amputation

NCT05560061
View directory record Official record
Conditions
Amputation
Interventions
Gait practice on an uneven terrain surface, Gait practice on a flat terrain surface
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees

NCT05267639
View directory record Official record
Conditions
Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User, Lower Limb Amputation Above Knee (Injury), Amputation; Traumatic, Leg: Thigh, Between Hip and Knee
Interventions
Power Knee
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Holliston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 2)

NCT04750538
View directory record Official record
Conditions
Pain Management
Interventions
BreEStim 120, BreEStim 240
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Jun 10, 2026, 10:17 PM EDT
Completed No phase listed Observational

Dual-tasking for Individuals With Lower Limb Amputation: Exploring the Relationship to Falls and Instrumental Activities of Daily Living

NCT05119192
View directory record Official record
Conditions
Amputation
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 89 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 14, 2024 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Design, Prototyping, and Testing of a Robotic Prosthetic Leg

NCT04616378
View directory record Official record
Conditions
Amputation; Traumatic, Leg, Lower
Interventions
Phase 2 Prescribed Prosthesis, Phase 2 Robotic Prosthetic Leg, Phase 3 No Prosthesis, Phase 3 Robotic Prosthetic Leg, Phase 3 Prescribed Prosthesis
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2022 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

Strength, Pain and Function in Operation Iraqi Freedom/Operation Enduring Freedom Amputees: A Nurse-Managed Program

NCT00942890
View directory record Official record
Conditions
Traumatic Amputation
Interventions
NMES (EMPI 300PV stimulator) plus standard of care, TMARP standard of care
Device · Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
3
States / cities
San Diego, California • Bethesda, Maryland • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 9, 2018 · Synced Jun 10, 2026, 10:17 PM EDT
Recruiting Not applicable Interventional

Improving Prosthetic Provision in Rural Communities: Limb Scanning With Caregiver Assistance

NCT05884203
View directory record Official record
Conditions
Lower Extremity Amputation
Interventions
Caregiver socket, Prosthetist socket
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Reality Treatment for Phantom Limb Pain

NCT03338842
View directory record Official record
Conditions
Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Phantom Limb Pain
Interventions
Distractor and Lower limb VR
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

Evidence Based Amputee Rehabilitation (EBAR) Program

NCT00126126
View directory record Official record
Conditions
Amputation Stumps, Diabetes Mellitus
Interventions
EBAR Program
Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
40 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 19, 2015 · Synced Jun 10, 2026, 10:17 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Stability and 3D Motion Study of an Experimental Prosthetic Foot

NCT00968292
View directory record Official record
Conditions
Amputation
Interventions
Experimental prosthetics foot (K3 Promoter)
Device
Lead sponsor
Tensegrity Prosthetics
Industry
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Arvada, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 27, 2009 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Phase 3 Interventional

Efficacy and Safety of XRP0038/NV1FGF in Critical Limb Ischemia Patients With Skin Lesions

NCT00566657
View directory record Official record
Conditions
Peripheral Vascular Diseases
Interventions
riferminogene pecaplasmid, Placebo (for riferminogene pecaplasmid)
Biological
Lead sponsor
Sanofi
Industry
Eligibility
50 Years and older
Enrollment
525 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated May 1, 2016 · Synced Jun 10, 2026, 10:17 PM EDT
Not listed Phase 3 Interventional

Once Daily Gabapentin in the Treatment of Post Amputation Pain

NCT01776671
View directory record Official record
Conditions
Pain, Quality of Life
Interventions
Gralise
Drug
Lead sponsor
Chicago Anesthesia Pain Specialists
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 13, 2017 · Synced Jun 10, 2026, 10:17 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Longitudinal Study of Weight Change Following Lower Limb Amputation

NCT00932399
View directory record Official record
Conditions
Amputation Wound, Traumatic Amputation of Toe, Dysvascular Amputation of Lower Limb
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
27 Years to 89 Years · Male only
Enrollment
4,549 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 7, 2016 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

Validation of Point Partial User Needs With Partial Finger Amputees

NCT05012657
View directory record Official record
Conditions
Amputation; Traumatic, Hand
Interventions
Point Partial
Device
Lead sponsor
Point Designs
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Aurora, Colorado • Lafayette, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 7, 2024 · Synced Jun 10, 2026, 10:17 PM EDT
Not yet recruiting Not applicable Interventional

Below-the-Knee Interventions for Limb Salvage: Use of Multifunctional Angioplasty Balloon Catheters

NCT06906055
View directory record Official record
Conditions
Peripheral Arterial Disease Below the Knee, Peripheral Arterial Disease, Rutherford 4 and 5 with Possibility to Improve Vascularization
Interventions
Multicath, Standard of Care (SOC)
Device
Lead sponsor
Summa Therapeutics, LLC
Industry
Eligibility
18 Years to 120 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Wilmington, Delaware • Vineland, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Jun 10, 2026, 10:17 PM EDT
Completed Not applicable Interventional Results available

Auto Control of Volume Management for Limb Loss

NCT03550118
View directory record Official record
Conditions
Lower Limb Amputation Below Knee (Injury)
Interventions
Adjustable socket
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Jun 10, 2026, 10:17 PM EDT