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Showing 1057–1080 of 1,419 matching trials from the live ClinicalTrials.gov search.
Conditions
Anesthesia, General
Interventions
Sedline
Device
Lead sponsor
Stanford University
Other
Eligibility
65 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
2
States / cities
Stanford, California • Philadelphia, Pennsylvania
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A PK/PD Study of Fospropofol Disodium Compared With Propofol Injectable Emulsion

NCT01260142
Conditions
Anesthesia
Interventions
Fospropofol disodium, propofol
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Study to Determine if Caffeine Accelerates Emergence From Anesthesia

NCT02567968
Conditions
Anesthesia
Interventions
Caffeine, Placebo Control
Drug
Lead sponsor
University of Chicago
Other
Eligibility
25 Years to 40 Years · Male only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Pelvic Organ Prolapse
Interventions
Bupivacaine liposomal, Lidocaine
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 95 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Hartford, Connecticut
Conditions
Brain Activity Related to Opioid Administration, Brain Activity Related to Drug Liking
Interventions
Observational study in patients receiving fentanyl for surgery
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years to 85 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Local Anesthesia
Interventions
lidocaine, sodium bicarbonate
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 100 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Anesthesia Morbidity, Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
Anesthesia Type
Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
12,466 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
South San Francisco, California
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Residual Neuromuscular Blockade in Cardiac Surgery Patients

NCT03574337
Conditions
Residual Neuromuscular Blockade
Interventions
Sugammadex, neostigmine/glycopyrolate
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Detroit, Michigan
Withdrawn Not applicable Interventional

The BALANCED Anaesthesia Study

NCT02073357
Conditions
Effect of General Anesthetic Dose on Recovery From Surgery
Interventions
Light general anaesthesia (BIS = 50), deep general anaesthesia (BIS = 35)
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
60 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
ENT Patients Scheduled for Surgery
Interventions
Not listed
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 89 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Redlands, California
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effects of Local Anesthesia on Post-operative Pain During Laparoscopic Inguinal Hernia Repair

NCT02055053
Conditions
Post Operative Pain (Post Laparoscopic Hernia Repair)
Interventions
0.5% Bupivicaine
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Burlington, Massachusetts
Completed Not applicable Interventional Results available

Effect of Location of Tetanic Stimuli on Photoplethysmogram

NCT03648853
Conditions
Stress Reaction
Interventions
Tetanic Stimulus
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
San Francisco, California
Conditions
Benign/Malignant Neoplasm, Long Bone Fracture
Interventions
propofol
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Newark, New Jersey
Conditions
Propofol Injection Pain in Children
Interventions
Buzzy device, Intravenous lidocaine
Device · Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
12 Years to 17 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Pain
Interventions
Lidocaine Cream 4%, Placebo
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
0 Days to 60 Days
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Buffalo, New York
Conditions
Anesthesia
Interventions
Dural puncture epidurals (DPE), Traditional epidurals (EPI), Combined-spinal epidural technique (CSE)
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Pain, Postoperative
Interventions
Ropivacaine infusion
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 4 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Surgery, Anesthesia, Children
Interventions
Not listed
Lead sponsor
The Society for Pediatric Anesthesia
Other
Eligibility
Up to 21 Years
Enrollment
5,000,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2040
U.S. locations
37
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Los Angeles, California + 32 more
Conditions
Orthopedic Surgery, Ventilation
Interventions
Low tidal Volume, High tidal Volume, Low PEEP, High PEEP
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
2,860 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Anesthesia, General
Interventions
SNAP monitor; Bispectral Index Monitor (BIS Monitor)
Device
Lead sponsor
Stryker Instruments
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
4
States / cities
Miami, Florida • Chicago, Illinois • Royal Oak, Michigan + 1 more
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Study of Remimazolam for Cataract Surgery

NCT07325227
Conditions
Cataract Surgery Anesthesia
Interventions
Arm 1 Cataract Surgery performed with remimazolam as sedative, Arm 2 Cataract Surgery performed with standard of care sedative
Drug
Lead sponsor
Fred E, Shapiro
Other
Eligibility
55 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Lower Limb Compression Prevents Hypotension After Epidural in Labor

NCT04750486
Conditions
Labor Pain, Maternal Hypotension
Interventions
Sequential compression devices
Device
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Carpal Tunnel Syndrome
Interventions
Decision Aid for Surgical Modality Choice
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Detroit, Michigan