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ClinicalTrials.gov public records Last synced Jul 22, 2026, 3:47 PM EDT

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Showing 1–24 of 1,306 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Anesthesia, Dental Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

TIVA vs TXA in Sinus Surgery to Evaluate Operative Blood Loss and Surgical Field Quality

NCT05639686
View directory record Official record
Conditions
Rhinosinusitis Chronic, Sinus Cancer, Sinus Polyp, Encephalocele
Interventions
Tranexamic acid injection, Total Intravenous Anesthesia, Inhalational isoflurane
Drug
Lead sponsor
Our Lady of the Lake Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Jul 22, 2026, 3:47 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Interscalene Block With Liposomal Bupivacaine vs. Interscalene Block With Bupivacaine and Adjuvants

NCT03845894
View directory record Official record
Conditions
Shoulder Arthroplasty
Interventions
Liposomal bupivacaine, Bupivacaine with adjuvants
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Jul 22, 2026, 3:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tegaderm vs. EyeGard for Eye Protection

NCT03549429
View directory record Official record
Conditions
Erythema
Interventions
Medical tapes: TegadermTM and EyeGard®
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Jul 22, 2026, 3:47 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Prospective Trial of Alerting to Extended Hypotensive Exposures on Long-Term Outcome After Surgery

NCT02217969
View directory record Official record
Conditions
Anesthesia, Hypotension
Interventions
Electronic alert to SLUScore increase
Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 13, 2018 · Synced Jul 22, 2026, 3:47 PM EDT
Terminated Not applicable Interventional Results available

Evaluation of Patient Reported Outcomes (PRO) After Total Knee Arthroplasty (TKA) Under Spinal Anesthesia

NCT03053453
View directory record Official record
Conditions
Knee Injuries
Interventions
Spinal Surgery, Verasense Knee System device
Procedure · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
50 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2023 · Synced Jul 22, 2026, 3:47 PM EDT
Recruiting Phase 4 Interventional

Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use

NCT06719180
View directory record Official record
Conditions
Hysterectomy, Post Operative Analgesia
Interventions
Bupivacain, Saline (NaCl 0,9 %) (placebo)
Drug · Other
Lead sponsor
MediSys Health Network
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Flushing, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Jul 22, 2026, 3:47 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

ED90 for Hyperbaric Bupivacaine in Super Obese Parturients

NCT03781388
View directory record Official record
Conditions
Obesity, Morbid, Spinal Anesthesia, Cesarean Delivery
Interventions
Bupivacaine
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Jul 22, 2026, 3:47 PM EDT
Not listed Not applicable Interventional

Esophageal Manometry During Recovery From Anesthesia: Pilot Study

NCT02661386
View directory record Official record
Conditions
Motility Function
Interventions
Motility Procedure
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Jul 22, 2026, 3:47 PM EDT
Completed Phase 4 Interventional Results available

Narcotic Free TIVA and Incidence of Unacceptable Movements Under Anesthesia During ACDF Surgery

NCT03643796
View directory record Official record
Conditions
Anterior Cervical Discectomy and Fusion (ACDF)
Interventions
Remifentanil, Ketamine, Dexmedetomidine
Drug
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2023 · Synced Jul 22, 2026, 3:47 PM EDT
Not listed No phase listed Observational

Effects of Postoperative Residual Paralysis on Hospital Costs

NCT01718860
View directory record Official record
Conditions
Residual Paralysis, Post-Anesthesia
Interventions
Quantitative measurement of neuromuscular transmission
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Jul 22, 2026, 3:47 PM EDT
Completed Phase 4 Interventional Results available

Using the SEDLine for the Titration of Sevoflurane in Elderly Patients Recovery Using the SEDLine TM for the Titration of Sevoflurane in Elderly Patients Undergoing Non-Cardiac Surgery After Beta-Adrenergic Blockade

NCT00938782
View directory record Official record
Conditions
Anesthesia, General
Interventions
Sedline
Device
Lead sponsor
Stanford University
Other
Eligibility
65 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
2
States / cities
Stanford, California • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2015 · Synced Jul 22, 2026, 3:47 PM EDT
Completed Phase 4 Interventional

General Anesthetics in CAncer REsection Surgery (GA-CARES) Trial

NCT03034096
View directory record Official record
Conditions
Anesthesia, General, Surgical Oncology
Interventions
Propofol, Volatile Agent
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
1,826 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
5
States / cities
Buffalo, New York • New Hyde Park, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Jul 22, 2026, 3:47 PM EDT
Completed Not applicable Interventional

Effect of Patient Preference for Intraoperative Opioid Use on Early Postoperative Quality of Recovery

NCT06855641
View directory record Official record
Conditions
Opioid Analgesia, Quality of Recovery (QoR-15), Outcome Assessment, Opioid Free Anesthesia
Interventions
Opioid based Anesthesia, opioid free anesthesia
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Jul 22, 2026, 3:47 PM EDT
Recruiting Phase 4 Interventional

The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

NCT06802224
View directory record Official record
Conditions
Anesthesia, Surgery With General Anesthesia, Noncardiac Surgery, Hypotension During Surgery, Acute Kidney Injury (AKI), Myocardial Injury After Noncardiac Surgery (MINS), Vasopressor
Interventions
Norepinephrine, Phenylephrine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
18,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
9
States / cities
San Francisco, California • College Park, Maryland • Ann Arbor, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Jul 22, 2026, 3:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery

NCT01550094
View directory record Official record
Conditions
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot, Complete Tear, Ankle and/or Foot Ligament, Pathological Fracture - Ankle and/or Foot, Loose Body in Joint of Ankle and/or Foot
Interventions
Not listed
Lead sponsor
Jose Soberon, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 13, 2015 · Synced Jul 22, 2026, 3:47 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Jet Injection of 1% Buffered Lidocaine Versus Topical ELA-Max for Anesthesia Prior to Intravenous (IV) Catheterization in Children

NCT00444756
View directory record Official record
Conditions
Pain
Interventions
J-tip jet injection of 1% buffered lidocaine
Procedure
Lead sponsor
Norton Healthcare
Other
Eligibility
8 Years to 15 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 7, 2007 · Synced Jul 22, 2026, 3:47 PM EDT
Completed Phase 2 Interventional Results available

Balloon REmodeling Antrostomy THErapy Study

NCT00645762
View directory record Official record
Conditions
Sinusitis
Interventions
RS-Series Rhinosinusitis Treatment System, FinESS Balloon
Device
Lead sponsor
Entellus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
13
States / cities
Fresno, California • Evanston, Illinois • Maywood, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2013 · Synced Jul 22, 2026, 3:47 PM EDT
Terminated Phase 2 Interventional Results available

Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy

NCT05017246
View directory record Official record
Conditions
Cancer Debulking, Enlarged Uterus, Fibroid Uterus, Adnexal Mass
Interventions
Bupivacaine, Morphine, Lidocaine
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Jul 22, 2026, 3:47 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

MRI of Glymphatic Clearance During Anesthetic Sedation

NCT02768688
View directory record Official record
Conditions
Glymphatic Flow
Interventions
Brain connectivity and physiology, Dexmedetomidine
Other · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
20 Years to 40 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Jul 22, 2026, 3:47 PM EDT
Recruiting Not applicable Interventional

SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke

NCT03737786
View directory record Official record
Conditions
Acute Stroke
Interventions
Tight control of end-tidal CO2 levels
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 110 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 25, 2025 · Synced Jul 22, 2026, 3:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid

NCT01350024
View directory record Official record
Conditions
Blepharoptosis
Interventions
Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine, Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine
Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 100 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Jul 22, 2026, 3:47 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Incidence of Difficult Airway and Difficult Neuraxial Placement in Obstetric Patients

NCT02193542
View directory record Official record
Conditions
Indication for Care or Intervention Related to Labor or Delivery With Baby Delivered
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 22, 2026, 3:47 PM EDT
Recruiting No phase listed Observational

The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes

NCT07022951
View directory record Official record
Conditions
Anesthesia, Sedation, Monitored Anesthesia Care, Procedure, Surgery, Day, Surgery, Surgery Scheduled, Fasting Before Operation, Aspiration; Gastric Contents, Anesthesia
Interventions
Preoperative fasting
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
1,200,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Jul 22, 2026, 3:47 PM EDT
Completed Not applicable Interventional Results available

Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia

NCT03734822
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
End tidal CO2 (EtCO2), Transcutaneous CO2 (TCO2), Capillary CO2 (CapCO2), Arterial blood gas (ABG)
Other · Device · Diagnostic Test
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Jul 22, 2026, 3:47 PM EDT