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ClinicalTrials.gov public records Last synced Oct 14, 2026, 5:23 AM EDT

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Showing 409–432 of 1,314 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anesthesia, Dental Clear all
Not listed Phase 2Phase 3 Interventional Accepts healthy volunteers

Subcutaneous Injection of Large Volumes of Tumescent Lidocaine and Epinephrine by Laypersons

NCT04733781
View directory record Official record
Conditions
Venomous Snakebites, Local Anesthesia, Painless Injection, Regional Anesthesia, Dermatologic Surgery, Cutaneous Pain, Musculoskeletal Pain
Interventions
Tumescent Lidocaine and Epinephrine
Drug
Lead sponsor
Jeffrey Alan Klein, MD
Industry
Eligibility
16 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
San Juan Capistrano, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Oct 14, 2026, 5:23 AM EDT
Active, not recruiting Phase 4 Interventional

The Effect of General Anesthesia on Pharmacokinetics of Oxycodone in Pediatric

NCT03054831
View directory record Official record
Conditions
Liquid Oxycodone
Interventions
liquid oxycodone
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 8 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Oct 14, 2026, 5:23 AM EDT
Terminated Not applicable Interventional Results available

Intravenous Versus Inhalational Anesthesia in Parkinson's Disease

NCT00615472
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Isoflurane, Remifentanil, Propofol
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 13, 2015 · Synced Oct 14, 2026, 5:23 AM EDT
Completed No phase listed Observational

Evaluation of Non-Invasive Respiratory Volume Monitor

NCT03039881
View directory record Official record
Conditions
Monitoring for Low Minute Ventilation Post Surgery
Interventions
Non-Invasive Respiratory Volume Monitor
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Oct 14, 2026, 5:23 AM EDT
Completed Not applicable Interventional

Erector Spinae Plane Versus Interscalene Blocks for Shoulder Surgery

NCT03807505
View directory record Official record
Conditions
Anesthesia, Local, Phrenic Nerve Paralysis, Upper Extremity Injury, Shoulder Injury
Interventions
Interscalene brachial plexus nerve block, Erector spinae plane block
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Oct 14, 2026, 5:23 AM EDT
Recruiting Early Phase 1 Interventional

Study Comparing Local/ MAC Anesthesia in Lumbar Decompression

NCT04992572
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Propofol Injection, Lidocaine Hydrochloride, Injectable
Drug
Lead sponsor
Stanford University
Other
Eligibility
40 Years to 95 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
2
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 14, 2026, 5:23 AM EDT
Completed Not applicable Interventional Results available

Opioid Use After Thyroid and Parathyroid Surgeries

NCT04955444
View directory record Official record
Conditions
Thyroidectomy, Parathyroidectomy, Opioid Use, Pain, Postoperative
Interventions
Quality improvement bundle
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Oct 14, 2026, 5:23 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effective Use of Pecs and Transversus Thoracics Plane Blocks for Subcutaneous Cardiac Pacemaker Insertion: A Case Series

NCT03899701
View directory record Official record
Conditions
Anesthesia, Local
Interventions
PEC I and PEC II blocks
Procedure
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2022 · Synced Oct 14, 2026, 5:23 AM EDT
Completed Phase 4 Interventional

Paravertebral Block to Reduce the Incidence of New Onset Atrial Fibrillation After Cardiac Surgery

NCT04472299
View directory record Official record
Conditions
New Onset Atrial Fibrillation, Anesthesia, Local, Cardiac Disease
Interventions
Ropivacaine 0.2% Injectable Solution
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Oct 14, 2026, 5:23 AM EDT
Completed Not applicable Interventional

Structural Modification In Supraglottic Airway Device

NCT04498598
View directory record Official record
Conditions
Airway Complication of Anesthesia, Ventilation Therapy; Complications, Hypoxia, Hypoventilation
Interventions
A/Z Supraglottic airway
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 14, 2026, 5:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mask Study: One-handed vs. Two Handed Technique in Children

NCT03215121
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
One handed mask airway, switch to two hands, Two handed mask airway + jaw thrust, Two handed mask airway, switch to one hand
Procedure
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
1 Year to 8 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jan 23, 2020 · Synced Oct 14, 2026, 5:23 AM EDT
Not yet recruiting Not applicable Interventional

MRI and Local Anesthesia

NCT07602686
View directory record Official record
Conditions
Dental Anesthesia
Interventions
ddMRI
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 14, 2026, 5:23 AM EDT
Completed Not applicable Interventional

Regional Anesthesia EMG Study

NCT06287151
View directory record Official record
Conditions
Surgery
Interventions
BlockSynop surface electromyography device, Clonidine, Sevoflurane
Device · Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
0 Years to 5 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 14, 2026, 5:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hemodynamic and Respiratory Variations During Laparoscopic Surgery With and Without Deep Neuromuscular Blockade.

NCT02025075
View directory record Official record
Conditions
Intraoperative Complications, Postoperative Complications, Laparoscopy, Surgical Complications From General Anesthesia, Ventilator-Induced Lung Injury
Interventions
Rocuronium
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 14, 2026, 5:23 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Decreasing Emergence Delirium With Personalized Music

NCT06236477
View directory record Official record
Conditions
Emergence Delirium
Interventions
Personalized Music, No Music
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
3 Years to 9 Years
Enrollment
394 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 14, 2026, 5:23 AM EDT
Terminated Not applicable Interventional Results available

Intraoperative Warming During Major Surgical Procedures Using the Esophageal Temperature Management System

NCT03790683
View directory record Official record
Conditions
Hypothermia Following Anesthesia, Hypothermia, Surgery
Interventions
EnsoETM, Surface Warming
Device
Lead sponsor
Advanced Cooling Therapy, Inc., d/b/a Attune Medical
Industry
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Oct 14, 2026, 5:23 AM EDT
Terminated Phase 4 Interventional Results available

Spinal Anesthesia in Total Hip Arthroplasty

NCT02818894
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
Lidocaine, Bupivacaine
Drug
Lead sponsor
Thomas L Bradbury
Other
Eligibility
18 Years to 90 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2022 · Synced Oct 14, 2026, 5:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Reality in Obstetric Patients

NCT03495531
View directory record Official record
Conditions
Obstetric Pain, Pain
Interventions
Virtual Reality
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Oct 14, 2026, 5:23 AM EDT
Terminated Not applicable Interventional Results available

Nerve Stimulator for Patients With Upper Extremity Disease, Vascular or Orthopedic Surgery

NCT03112642
View directory record Official record
Conditions
Other Biomechanical Lesions of Upper Extremity
Interventions
Local anesthetic block [0.35% marcaine], Braun DIG-R-C Stimuplex Blockade Monitor System
Procedure · Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
21 Years to 89 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 14, 2026, 5:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Two Injection Sites of Local Anesthetic for Hand Surgery

NCT02112006
View directory record Official record
Conditions
Hand Injury, Wrist Injury, Finger Injury
Interventions
0.5% bupivacaine injected in the forearm, 20-30ml of 0.5% bupivacaine.
Procedure
Lead sponsor
Jose Soberon, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 22, 2016 · Synced Oct 14, 2026, 5:23 AM EDT
Not listed Not applicable Interventional

Comparison Study of Intraoperative Patient Warming Systems

NCT00670826
View directory record Official record
Conditions
Orthopedic Surgery, General Anesthesia
Interventions
vitalHEAT vH2 Temperature Management System, Arizant Healthcare Bair Hugger Temperature Management System
Device
Lead sponsor
Dynatherm Medical Inc.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 2, 2008 · Synced Oct 14, 2026, 5:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effect of Night Float Call on Sleep and Activity Patterns Among Anesthesia Residents

NCT05043038
View directory record Official record
Conditions
Sleep Disorder, Shift Work, Fatigue, Sleep Disturbance
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Dec 18, 2024 · Synced Oct 14, 2026, 5:23 AM EDT
Recruiting Phase 3 Interventional Accepts healthy volunteers

Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration Repairs

NCT06910241
View directory record Official record
Conditions
Laceration of Skin
Interventions
Lidocaine, Diphenhydramine
Drug
Lead sponsor
Florida Atlantic University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boynton Beach, Florida
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 14, 2026, 5:23 AM EDT
Not yet recruiting Phase 3 Interventional

Methadone for Enhanced Postoperative Analgesia in Intermediate-Risk Noncardiac Surgery (MELODY)

NCT07565870
View directory record Official record
Conditions
Postoperative Pain, Recovery
Interventions
Intravenous Methadone, Short-acting Opioids Intraoperative analgesia
Drug
Lead sponsor
Alexandre P. Joosten
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 14, 2026, 5:23 AM EDT