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ClinicalTrials.gov public records Last synced Oct 14, 2026, 5:58 AM EDT

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Showing 433–456 of 1,314 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anesthesia, Dental Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Virtual Reality on Pre-Operative Anxiety and Induction of Anesthesia in Children and Adolescents

NCT03239743
View directory record Official record
Conditions
Tonsillectomy
Interventions
Virtual Reality, Midazolam
Device · Drug
Lead sponsor
Valley Anesthesiology Consultants
Other
Eligibility
5 Years to 11 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 19, 2018 · Synced Oct 14, 2026, 5:58 AM EDT
Suspended Phase 2 Interventional Accepts healthy volunteers

A Study of Human Multi-Sensory Integration

NCT03498391
View directory record Official record
Conditions
Anesthesia Awareness
Interventions
Propofol, Ketamine Injectable Product
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 14, 2026, 5:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Pilot Analysis of the Association Between Anesthesia Induction Dosing and AKI in the Elderly Population

NCT03699696
View directory record Official record
Conditions
Acute Kidney Injury, Hypotension, Anesthesia; Adverse Effect
Interventions
Propofol
Drug
Lead sponsor
Yale University
Other
Eligibility
65 Years and older
Enrollment
541 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Oct 14, 2026, 5:58 AM EDT
Completed Phase 4 Interventional

Mepivacaine vs Bupivacaine Spinal Anesthesia for TKA

NCT06291727
View directory record Official record
Conditions
Anesthesia, Spinal, Arthroplasty, Replacement, Knee
Interventions
Mepivacaine, Bupivacaine
Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Oct 14, 2026, 5:58 AM EDT
Terminated Not applicable Interventional Results available

Comparison of 3 Direct Laryngoscopes for Tracheal Intubation in Patients Undergoing Lumbar Spine Surgery

NCT02955511
View directory record Official record
Conditions
Anesthesia, Airway
Interventions
Blade MAC size 3, Blade MAC size 3.5, Inscope Blade size 3.5
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Oct 14, 2026, 5:58 AM EDT
Not listed Phase 2 Interventional

Effect of Pectoral Nerve Block on Post-op Pain in Patients Undergoing Mastectomy and Immediate Reconstruction

NCT02913573
View directory record Official record
Conditions
Breast Neoplasm
Interventions
Ultrasound, 0.25% bupivacaine
Device · Drug
Lead sponsor
Huntington Memorial Hospital
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2016 · Synced Oct 14, 2026, 5:58 AM EDT
Completed Not applicable Interventional

Pain Management After TKA: Comparison of Short- and Long-term Nerve Blocks

NCT03245359
View directory record Official record
Conditions
Anesthesia, Local, Pain, Postoperative
Interventions
Short-term ON-Q, Short-term ON-Q, Long-term ON-Q, Long-term ON-Q
Device · Drug
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 2, 2019 · Synced Oct 14, 2026, 5:58 AM EDT
Completed Not applicable Interventional

Dexmedetomidine After Cesarean for the Treatment of Nausea and Shivering

NCT03370562
View directory record Official record
Conditions
Shivering, Nausea and Vomiting, Postoperative
Interventions
Dexmedetomidine, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 1, 2021 · Synced Oct 14, 2026, 5:58 AM EDT
Recruiting Not applicable Interventional

Non-inferiority Trial Between Sotair® Device Attached to Manual Resuscitator Versus Mechanical Ventilation

NCT06117683
View directory record Official record
Conditions
Airway Management, Respiration, Artificial
Interventions
ADULT Sotair Device
Device
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 14, 2026, 5:58 AM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Parturient Controlled Epidural Analgesia (PCEA) With or Without a Basal Infusion for Early Labor

NCT00871442
View directory record Official record
Conditions
Labor Pain
Interventions
No Basal Infusion, Basal infusion, PCEA solution (bupivacaine and fentanyl)
Other · Drug
Lead sponsor
Neil Roy Connelly, MD
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2015 · Synced Oct 14, 2026, 5:58 AM EDT
Recruiting Phase 4 Interventional

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

NCT05029726
View directory record Official record
Conditions
Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis, Lumbar Radiculopathy, Lumbar Spine Instability, Synovial Cyst, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Intervertebral Discs
Interventions
Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
Drug
Lead sponsor
John O'Toole
Other
Eligibility
18 Years to 80 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 14, 2026, 5:58 AM EDT
Completed No phase listed Observational

Assessment of Ventilatory Management During General Anesthesia for Robotic Surgery

NCT02989415
View directory record Official record
Conditions
Robotic Surgery, Mechanical Ventilation
Interventions
Mechanical Ventilation
Other
Lead sponsor
Hospital Israelita Albert Einstein
Other
Eligibility
18 Years and older
Enrollment
1,015 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
4
States / cities
San Francisco, California • Boston, Massachusetts • Rochester, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Oct 14, 2026, 5:58 AM EDT
Active, not recruiting Phase 4 Interventional

Oral Methadone in Cardiac Surgery

NCT07221617
View directory record Official record
Conditions
Pain, Postoperative, Anesthesia, Cardiac Surgery
Interventions
Methadone, oral, Methadone, intravenously
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 14, 2026, 5:58 AM EDT
Completed Phase 2 Interventional Results available

Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures

NCT01516684
View directory record Official record
Conditions
Malignant Neoplasm
Interventions
placebo administration, EMLA, propofol, fentanyl citrate
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 22 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 14, 2026, 5:58 AM EDT
Completed Phase 4 Interventional

Evaluation of Vitrase as an Adjuvant to Increase Absorption and Dispersion of Other Injected Anesthetics

NCT00198549
View directory record Official record
Conditions
Pain
Interventions
Vitrase (ovine hyaluronidase) Lyophilized
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 19, 2013 · Synced Oct 14, 2026, 5:58 AM EDT
Completed No phase listed Observational Results available

Pediatric Temperature Variation in the MRI Scanner Under General Anesthesia

NCT01119248
View directory record Official record
Conditions
Children Requiring MRI
Interventions
axillary temperature before MRI and after the MRI
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
6 Months to 8 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced Oct 14, 2026, 5:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cognitive Effects of Anesthesia on Children

NCT02005185
View directory record Official record
Conditions
Procedures Requiring Anesthesia
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
6 Years to 11 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
3
States / cities
Davis, California • Oakland, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2020 · Synced Oct 14, 2026, 5:58 AM EDT
Completed Phase 4 Interventional

Transthecal Metacarpal Block Versus Traditional Digital Block for Painful Finger Procedures in Children

NCT00130104
View directory record Official record
Conditions
Finger Injuries
Interventions
Transthecal Metacarpal Block
Procedure
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 18 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2007 · Synced Oct 14, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

Ultrasound-image Guided Versus Doppler Guided Versus Palpation Technique for Arterial Cannulation in Adults

NCT01276171
View directory record Official record
Conditions
Anesthesia
Interventions
Ultrasound, Doppler, Palpation
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 99 Years
Enrollment
749 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Oct 14, 2026, 5:58 AM EDT
Completed Phase 4 Interventional Results available

Pectoralis Block vs Paravertebral Nerve Blocks for Breast Surgery

NCT04742309
View directory record Official record
Conditions
Breast Surgery
Interventions
Pecs-2 block (single injection), Paravertebral block (single injection)
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Oct 14, 2026, 5:58 AM EDT
Completed Phase 4 Interventional

Study Evaluating Whether the Bispectral Index Prevents Patients at Higher Risk From Being Awake During Surgery and Anesthesia

NCT00682825
View directory record Official record
Conditions
Explicit Recall of Intra-Operative Events
Interventions
Bispectral index protocol, End tidal anesthetic gas-guided
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
2
States / cities
Chicago, Illinois • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 4, 2011 · Synced Oct 14, 2026, 5:58 AM EDT
Completed No phase listed Observational Results available

In-vitro Study to Assess the Coagulation Effects of Exogenous Oxytocin Using Thromboelastography.

NCT00788255
View directory record Official record
Conditions
Anesthesia
Interventions
Final exogenous oxytocin concentration=22.5 μU/mL, Final exogenous oxytocin concentration=30.1μU/mL, Final exogenous oxytocin concentration=32.9μU/mL
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2016 · Synced Oct 14, 2026, 5:58 AM EDT
Completed Not applicable Interventional Results available

King Vision Video Laryngoscope Ambu (aBlade) System for Use in Children

NCT02841189
View directory record Official record
Conditions
Pediatric Anesthesia, King Vision Video Laryngoscope Intubation
Interventions
King Vision video Laryngoscope
Device
Lead sponsor
Indiana University
Other
Eligibility
1 Month to 10 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 14, 2026, 5:58 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment

NCT03799484
View directory record Official record
Conditions
Forehead Rhytides, Forehead Wrinkles
Interventions
Botulinum toxin type A, 2.5% lidocaine/2.5% prilocaine, petrolatum ointment
Drug · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Oct 14, 2026, 5:58 AM EDT