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ClinicalTrials.gov public records Last synced Oct 15, 2026, 5:25 PM EDT

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Showing 697–720 of 1,314 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anesthesia, Dental Clear all
Recruiting Phase 3 Interventional

Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)

NCT05358535
View directory record Official record
Conditions
Anesthesia, Propofol Adverse Reaction, Etomidate Adverse Reaction, Anesthesia Complication, Anesthesia; Adverse Effect, Anesthesia; Reaction
Interventions
Admixture of propofol and etomidate at a ratio by volume of 75%/25% (P7E2), Admixture of propofol and etomidate at a ratio by volume of 25%/75% (P2E7)
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Phase 3 Interventional Results available

Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery

NCT02423876
View directory record Official record
Conditions
Intraoperative Complication, Malignant Female Reproductive System Neoplasm, Pain
Interventions
Epidural analgesia, Intraoperative Complication Management and Prevention, Pain Therapy
Drug · Other · Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older · Female only
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Oct 15, 2026, 5:25 PM EDT
Terminated Phase 4 Interventional Results available

Deep Brain Stimulation (DBS) Sedation

NCT03283150
View directory record Official record
Conditions
Brain, Sedation
Interventions
Remifentanil, Propofol, Dexmedetomidine
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 5, 2024 · Synced Oct 15, 2026, 5:25 PM EDT
Terminated Not applicable Interventional Results available

Evaluation of Patient Reported Outcomes (PRO) After Total Knee Arthroplasty (TKA) Under Spinal Anesthesia

NCT03053453
View directory record Official record
Conditions
Knee Injuries
Interventions
Spinal Surgery, Verasense Knee System device
Procedure · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
50 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Early Phase 1 Interventional Results available

Caffeine and Neurologic Recovery Following Surgery and General Anesthesia

NCT03577730
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Caffeine Citrate, Dextrose Water
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 6, 2021 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Phase 4 Interventional Results available

Best Management of Muscle Relaxation- Objective Monitoring

NCT03958201
View directory record Official record
Conditions
Residual Paralysis, Post Anesthesia
Interventions
Protocol for Management of Muscle Relaxation With Rocuronium Using Objective Monitoring and Reversal With Neostigmine or Sugammadex
Combination Product
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a New Training Model for Ultrasound Guided Regional Anesthesia - A Feasibility Study

NCT02370472
View directory record Official record
Conditions
Regional Anesthesia
Interventions
tool developed using cameras and a computer
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
25 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 2, 2018 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy

NCT04440475
View directory record Official record
Conditions
Anesthesia, Local, Prolapse, Prolapse; Female, Prolapse, Vaginal, Prolapse; Vagina, Posthysterectomy, Pain, Postoperative
Interventions
TAP block
Procedure
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Not applicable Interventional Results available

Splanchnic Nerve Anesthesia in Heart Failure

NCT02669407
View directory record Official record
Conditions
Heart Failure
Interventions
splanchnic nerve anesthesia with a local anesthetic, regional nerve block with a local anesthetic (Lidocaine)
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 90 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 6, 2019 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Risk of Oxygen During Cardiac Surgery Trial

NCT02361944
View directory record Official record
Conditions
Cardiac Surgery
Interventions
Oxygen - normoxia, Oxygen - hyperoxia
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Oct 15, 2026, 5:25 PM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Regional Anesthesia Block in Fibula Free Flap Reconstruction

NCT03906838
View directory record Official record
Conditions
Anesthesia, Local, Surgery, Opioid Use, Pain, Postoperative, Head and Neck Neoplasms
Interventions
Ropivacaine injection
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Oct 15, 2026, 5:25 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effect of a Mental Wellness App on the Mental Wellness of Medical and Nurse Anesthesia Students

NCT05925062
View directory record Official record
Conditions
Mental Health Issue
Interventions
QActual
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sedline EEG Guided Depth of Anesthesia

NCT05051982
View directory record Official record
Conditions
Anesthesia, Surgery
Interventions
Sedline EEG in View
Device
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Not applicable Interventional

A Study of the Effect of Arterial Carbon Dioxide Tension on the Recovery of Spontaneous Respiration

NCT01733446
View directory record Official record
Conditions
Surgery, Anesthesia
Interventions
Continuation of High Frequency Jet Ventilation (HFJV)
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 23, 2018 · Synced Oct 15, 2026, 5:25 PM EDT
Completed No phase listed Observational

Perioperative Local Anesthesia Block in Spine Surgery

NCT05094427
View directory record Official record
Conditions
Lumbar Spine Disease, Lumbar Disc Herniation, Lumbar Spinal Stenosis
Interventions
Preoperative fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
232 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Oct 15, 2026, 5:25 PM EDT
Completed No phase listed Observational

Tongue Pull Versus Jaw Thrust

NCT00833118
View directory record Official record
Conditions
Surgery
Interventions
Jaw thrust maneuver (Intubation)
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 12, 2010 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Dexmedetomidine of Gastrointestinal Motility

NCT04798482
View directory record Official record
Conditions
Anesthesia
Interventions
Dexmedetomidine
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
3 Years to 18 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Phase 4 Interventional Results available

Comparing Local Anesthetics for TAP Block During Abdominally-based Free Flap for Breast Reconstruction

NCT03700970
View directory record Official record
Conditions
Breast Reconstruction, Anesthesia, Transverse Abdominis Plane Block
Interventions
Liposomal bupivacaine, Regular bupivacaine
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Oct 15, 2026, 5:25 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Incidence of Difficult Airway and Difficult Neuraxial Placement in Obstetric Patients

NCT02193542
View directory record Official record
Conditions
Indication for Care or Intervention Related to Labor or Delivery With Baby Delivered
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

MRI of Glymphatic Clearance During Anesthetic Sedation

NCT02768688
View directory record Official record
Conditions
Glymphatic Flow
Interventions
Brain connectivity and physiology, Dexmedetomidine
Other · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
20 Years to 40 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Phase 4 Interventional Results available

Sugammadex Versus Neostigmine for Reversal of Rocuronium Neuromuscular

NCT03322657
View directory record Official record
Conditions
Neuromuscular Blockade, Anesthesia
Interventions
Neostigmine, Glycopyrrolate, Sugammadex
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 16, 2021 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Clinical Evaluation of no Needle Dental Anesthesia Compared to Syringe Anesthesia Delivery

NCT06874244
View directory record Official record
Conditions
Local Anesthesia Injection Pain
Interventions
Local Anesthesia (lidocaine hydrochloride), Iontophoresis of Tetracaine and oxymetazoline
Drug
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Use of an Adaptive Sensory Environment in Autism Spectrum Disorder (ASD) Patients in the Perioperative Environment

NCT04994613
View directory record Official record
Conditions
Autism Spectrum Disorder, Anesthesia, Procedural Anxiety, Sensory Processing Disorder
Interventions
Sensory adaptive environment
Other
Lead sponsor
Dayton Children's Hospital
Other
Eligibility
3 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 28, 2023 · Synced Oct 15, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade

NCT03677778
View directory record Official record
Conditions
Anesthesia, Local, Phrenic Nerve Paralysis, Upper Extremity Injury, Phrenic Nerve Palsy on the Left, Phrenic Nerve Palsy on the Right
Interventions
Normal saline injected via interscalene nerve catheter, Placebo
Procedure · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Oct 15, 2026, 5:25 PM EDT