Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 16, 2026, 8:19 AM EDT

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Showing 937–960 of 1,314 matching trials from the live ClinicalTrials.gov search.
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Influence of Lidocaine Infusion on Motor Evoked Potential Thresholds

NCT06792474
Conditions
Spinal Disease, Anesthesia, Post Operative Pain
Interventions
Lidocaine in Saline, Normal saline
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Lebanon, New Hampshire
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Anesthetic Technique on NK Cells

NCT02669186
Conditions
Pain, Anesthesia, Cancer
Interventions
Bupivacaine + Fentanyl, Bupivacaine
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Adolescent Idiopathic Scoliosis, Juvenile Idiopathic Scoliosis
Interventions
Methadone, Liposomal bupivacaine (LB, Exparel)
Drug
Lead sponsor
Dr. Casey Stondell, MD
Other
Eligibility
11 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Conditions
Hypotension, Arterial Stiffness
Interventions
SphygmoCor system
Device
Lead sponsor
University of Iowa
Other
Eligibility
50 Years to 85 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Hysterectomy, Post Operative Analgesia
Interventions
Bupivacain, Saline (NaCl 0,9 %) (placebo)
Drug · Other
Lead sponsor
MediSys Health Network
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Flushing, New York
Conditions
Lung Volume Reduction Surgery
Interventions
Propofol, Desflurane
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
New York, New York
Active, not recruiting Not applicable Interventional

Sonographic Assessment of Cricoid Pressure

NCT04190524
Conditions
Aspiration; Gastric Contents, Anesthesia, Intubation Complication
Interventions
Application of cricoid pressure, Application of Left lateral paratracheal pressure
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 17 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

Opioid Use After Thyroid and Parathyroid Surgeries

NCT04955444
Conditions
Thyroidectomy, Parathyroidectomy, Opioid Use, Pain, Postoperative
Interventions
Quality improvement bundle
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Postoperative Opioids in Patients Undergoing Laparoscopic Hiatal Hernia

NCT05953428
Conditions
Hiatal Hernia
Interventions
Opioid Sparing Anesthesia Protocol (OSA), Opioid Based Anesthesia Protocol (OBA)
Other
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Evanston, Illinois
Conditions
Anxiety, Hypotension
Interventions
Pandora Music, Mozart Music
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Airway Management Skills Amongst Anesthesia Providers

NCT05055401
Conditions
Airway Management
Interventions
Direct Laryngoscopy, Laryngeal Mask Airways, Video Laryngoscopy
Procedure
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
Not listed
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Greenville, South Carolina
Completed Early Phase 1 Interventional Accepts healthy volunteers

MRI of Glymphatic Clearance During Anesthetic Sedation

NCT02768688
Conditions
Glymphatic Flow
Interventions
Brain connectivity and physiology, Dexmedetomidine
Other · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
20 Years to 40 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Results available

Pharmacokinetics of Ketamine in Infants and Children

NCT00553839
Conditions
The Pk of IV Ketamine in Children With Heart Disease
Interventions
ketamine hydrochloride
Drug
Lead sponsor
Stanford University
Other
Eligibility
Up to 17 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Palo Alto, California • Denver, Colorado
Conditions
Pain During and After Endovenous Laser Obliteration of Large Saphenous Vein Based on Lidocaine Tumescent Concentration
Interventions
Lidocaine
Drug
Lead sponsor
Midwest Vein Center
Other
Eligibility
16 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2014
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Breast Surgery
Interventions
Erector Spinae (single injection), Paravertebral (single injection)
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
San Diego, California
Completed Phase 3 Interventional Results available

Regional Anesthesia and Breast Cancer Recurrence

NCT00418457
Conditions
Breast Neoplasms
Interventions
General anesthesia and opioids, Regional analgesia and propofol
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
2,108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Venomous Snakebites, Local Anesthesia, Painless Injection, Regional Anesthesia, Dermatologic Surgery, Cutaneous Pain, Musculoskeletal Pain
Interventions
Tumescent Lidocaine and Epinephrine
Drug
Lead sponsor
Jeffrey Alan Klein, MD
Industry
Eligibility
16 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
San Juan Capistrano, California
Conditions
Drug Reaction to Analgesic Nos
Interventions
RX0041 4%, Placebo, RX0041 8%
Drug
Lead sponsor
Pharmaceutical Project Solutions, Inc.
Industry
Eligibility
18 Years and older
Enrollment
648 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Mount Arlington, New Jersey • Columbia, South Carolina
Conditions
Respiratory Complications
Interventions
Respiratory Motion Inc
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Year to 17 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Benign/Malignant Neoplasm, Long Bone Fracture
Interventions
propofol
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Newark, New Jersey
Conditions
Anesthesia, Pediatrics
Interventions
Inhalation induction with parosmia
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
5 Years to 13 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Analgesia, Pain
Interventions
20 ml of ropivacaine 0.5%, 30 ml of ropivacaine 0.5%, 40 ml of ropivacaine 0.5%
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Results available

Methadone in Ambulatory Surgery

NCT02300077
Conditions
Post-operative Pain, Anesthesia
Interventions
methadone, Control (Intra-operative administration of opioids, other than methadone)
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Hypotension, Pregnancy
Interventions
ondansetron, placebo
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Charlottesville, Virginia