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ClinicalTrials.gov public records Last synced Oct 20, 2026, 7:02 AM EDT

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Showing 1–24 of 252 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anesthesia, General Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Task-based Credentialing for Medical Officers in Spinal Anesthesia

NCT04438811
View directory record Official record
Conditions
Spinal Anesthesia, Task Sharing in Anesthetic Delivery in Areas With Limited Access to Care
Interventions
delivery of the spinal anesthetic by a trained medical officer, delivery of spinal anesthetic by a consultant anesthetist
Other
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years to 65 Years
Enrollment
486 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Oct 20, 2026, 7:02 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Airway Management and Weight in Children

NCT03996343
View directory record Official record
Conditions
Perioperative Respiratory Adverse Events, Airway Management
Interventions
Endotracheal intubation, Laryngeal mask airway
Device
Lead sponsor
University of Michigan
Other
Eligibility
2 Years to 17 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 24, 2019 · Synced Oct 20, 2026, 7:02 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

EEG Studies of Sevoflurane-Induced General Anesthesia

NCT03503578
View directory record Official record
Conditions
Anesthesia
Interventions
Sevoflurane, Ketamine
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced Oct 20, 2026, 7:02 AM EDT
Completed Phase 3 Interventional

Comparison of Paravertebral Block With General Anesthesia in Patients Undergoing Breast Cancer Surgery

NCT00645138
View directory record Official record
Conditions
Breast Cancer
Interventions
Paravertebral Block, General Anesthesia
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 5, 2011 · Synced Oct 20, 2026, 7:02 AM EDT
Recruiting Not applicable Interventional

Impact of Intraoperative Oxygenation Practices on Patient Outcomes

NCT07224243
View directory record Official record
Conditions
Surgeries Undergoing General Anesthesia
Interventions
Lower FiO2, Intermediate FiO2, Higher FiO2
Other
Lead sponsor
Frederic T Billings IV
Other
Eligibility
18 Years and older
Enrollment
54,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Ann Arbor, Michigan • Omaha, Nebraska • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 20, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

A Comparison of Different Ventilation Strategies in Infants Using the PLMA™

NCT03235817
View directory record Official record
Conditions
Ventilation
Interventions
Spontaneous ventilation, Pressure support ventilation, Pressure control ventilation
Other · Device
Lead sponsor
Wake Forest University
Other
Eligibility
1 Month to 11 Months
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2022 · Synced Oct 20, 2026, 7:02 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Comparative Analysis of Spinal Anesthesia Versus General Anesthesia for vNOTES

NCT05688943
View directory record Official record
Conditions
Anesthesia, Tubal Ligation
Interventions
Spinal Anesthesia, General Anesthesia
Procedure
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
21 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 20, 2026, 7:02 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Dose-Finding and Human Abuse Potential Study Of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users

NCT05614544
View directory record Official record
Conditions
General Anesthesia
Interventions
HSK3486, Propofol, Placebo
Drug
Lead sponsor
Haisco-USA Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 13, 2023 · Synced Oct 20, 2026, 7:02 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia?

NCT01737593
View directory record Official record
Conditions
Emergence Agitation, Pain
Interventions
Acetaminophen
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
6 Months to 6 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 21, 2016 · Synced Oct 20, 2026, 7:02 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Does Spinal Anesthesia for Prolapse Surgery With Lead to Urinary Retention?

NCT02547155
View directory record Official record
Conditions
Urinary Retention, Uterine Prolapse
Interventions
Spinal anesthesia, General anesthesia
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Oct 20, 2026, 7:02 AM EDT
Enrolling by invitation Phase 3 Interventional Accepts healthy volunteers

GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries

NCT05444751
View directory record Official record
Conditions
Lumbar Disc Herniation, Lumbar Disc Disease, Lumbar Radiculopathy
Interventions
General anesthetic, SA + ESP
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 20, 2026, 7:02 AM EDT
Completed No phase listed Observational

Prognostic Factors Associated With Postoperative Cognitive Dysfunction After Surgery

NCT03443440
View directory record Official record
Conditions
Postoperative Cognitive Dysfunction
Interventions
Neurocognitive Testing
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
50 Years to 99 Years
Enrollment
57 participants
Timeline
2018 – 2020
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Oct 20, 2026, 7:02 AM EDT
Terminated Phase 2 Interventional Results available

Chloroprocaine Spinal for Outpatient Knee Surgery

NCT03365752
View directory record Official record
Conditions
Knee Arthroscopy
Interventions
Chloroprocaine, Mepivacaine, General Anesthetics
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2022 · Synced Oct 20, 2026, 7:02 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

NCT07203287
View directory record Official record
Conditions
Post Operative Pulmonary Complications, Neuromuscular Blockade, General Anesthesia
Interventions
Rocuronium, Cisatracurium, Sugammadex, Neostigmine
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 80 Years
Enrollment
490 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 20, 2026, 7:02 AM EDT
Completed Not applicable Interventional

Acupuncture for the Prevention of Emergence Delirium in Children Undergoing Myringotomy Tube Placement

NCT02383004
View directory record Official record
Conditions
Delirium, Psychomotor Agitation
Interventions
Acupuncture
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
1 Year to 6 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 18, 2017 · Synced Oct 20, 2026, 7:02 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Continuous Interscalene Block Results in Superior Recovery Throughout the First Postoperative Week

NCT01881776
View directory record Official record
Conditions
Postoperative Pain, Adverse Effects
Interventions
ISB
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 75 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2014 · Synced Oct 20, 2026, 7:02 AM EDT
Completed No phase listed Observational

Evaluation of Non-Invasive Respiratory Volume Monitor

NCT03039881
View directory record Official record
Conditions
Monitoring for Low Minute Ventilation Post Surgery
Interventions
Non-Invasive Respiratory Volume Monitor
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Oct 20, 2026, 7:02 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Study to Determine the Pharmacokinetics and Pharmacodynamic Effects of Phenylephrine on BP Via IV

NCT02323399
View directory record Official record
Conditions
Hypotension
Interventions
Phenylephrine
Drug
Lead sponsor
West-Ward Pharmaceutical
Industry
Eligibility
12 Years to 16 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2024
U.S. locations
10
States / cities
Wilmington, Delaware • Washington D.C., District of Columbia • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Oct 20, 2026, 7:02 AM EDT
Completed No phase listed Observational

Provider Variability in the Use of Neuromuscular Blocking Drugs and Reversal

NCT03585348
View directory record Official record
Conditions
Neuromuscular Blockade, Residual Curarisation, Postoperative, Surgery Under General Anaesthesia
Interventions
Neuromuscular blocking agents
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
265,537 participants
Timeline
2018 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 20, 2026, 7:02 AM EDT
Completed Not applicable Interventional Results available

Inducibility and Stability of Ventricular Tachycardia Inpatients Undergoing VT Ablation Under General Anesthesia

NCT02419547
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Versed, Fentanyl, Propofol, Sevoflurane
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 9, 2019 · Synced Oct 20, 2026, 7:02 AM EDT
Recruiting Phase 4 Interventional

Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia

NCT06757075
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Ibuprofen, Acetominophen
Drug
Lead sponsor
Boston University
Other
Eligibility
4 Years to 6 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Brighton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 20, 2026, 7:02 AM EDT
Completed No phase listed Observational Results available

Pediatric Temperature Variation in the MRI Scanner Under General Anesthesia

NCT01119248
View directory record Official record
Conditions
Children Requiring MRI
Interventions
axillary temperature before MRI and after the MRI
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
6 Months to 8 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced Oct 20, 2026, 7:02 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Isoflurane at Subanesthetic Concentrations - 6

NCT00000254
View directory record Official record
Conditions
Opioid-Related Disorders, Substance-Related Disorders
Interventions
40% Nitrous oxide, Sham comparator, 0.2% isoflurane, 0.4% isoflurane, 0.6% isoflurane
Drug · Other
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 34 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1995
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Oct 20, 2026, 7:02 AM EDT
Completed Phase 4 Interventional

Light Sedation or Intubated General Anesthesia in Patients With Brain Cancer Undergoing Craniotomy

NCT02193568
View directory record Official record
Conditions
Adult Brain Tumor
Interventions
Arm I (light sedation), Arm II (intubated general anesthesia), Arm II (intubated general anesthesia), Arm I (light sedation)
Procedure · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
19 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 13, 2019 · Synced Oct 20, 2026, 7:02 AM EDT