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ClinicalTrials.gov public records Last synced Oct 22, 2026, 7:28 PM EDT

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Showing 217–240 of 252 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anesthesia, General Clear all
Completed No phase listed Observational

Functional Near Infrared Spectroscopy to Detect Pain in Young Children Under General Anesthesia

NCT04362423
View directory record Official record
Conditions
Pain
Interventions
fNIRS
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Month to 16 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Not applicable Interventional

Hyperoxia on Ventilation During Recovery From General Anesthesia

NCT05922020
View directory record Official record
Conditions
Ventilatory Depression, Postoperative Respiratory Failure
Interventions
Oxygen gas
Other
Lead sponsor
Stanford University
Other
Eligibility
20 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2024 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Reversal of General Anesthesia With Methylphenidate

NCT02051452
View directory record Official record
Conditions
Post Operative Cognitive Dysfunction, Emergence From Anesthesia
Interventions
Methylphenidate, Saline
Drug · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 22, 2019 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Not applicable Interventional

Protective Ventilation With Higher Versus Lower PEEP During General Anesthesia for Surgery in Obese Patients

NCT02148692
View directory record Official record
Conditions
Morbid Obesity, Surgery, General Anesthesia
Interventions
Higher PEEP, Lower PEEP
Procedure
Lead sponsor
Technische Universität Dresden
Other
Eligibility
18 Years and older
Enrollment
2,013 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 3, 2019 · Synced Oct 22, 2026, 7:28 PM EDT
Terminated No phase listed Observational

Recovery of Ventilation After General Anesthesia in Morbidly Obese Patients

NCT03925610
View directory record Official record
Conditions
Morbid Obesity, Opioid-Related Disorders, Surgery--Complications, Sleep Apnea Syndromes
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2021 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Cardiovascular Effects of Racemic Epinephrine Pellets

NCT04688346
View directory record Official record
Conditions
Epinephrine Causing Adverse Effects in Therapeutic Use
Interventions
HemeRX epinephrine pellets
Drug
Lead sponsor
University of Washington
Other
Eligibility
2 Years to 9 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Phase 4 Interventional Results available

Effect of Dexmedetomidine on Emergence Agitation in Children With or Without Tube Insertion Under General Anesthesia

NCT01535287
View directory record Official record
Conditions
Myringotomy
Interventions
Dexmedetomidine
Drug
Lead sponsor
Martin Mueller
Other
Eligibility
1 Year to 10 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 9, 2018 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Dose-Finding and Human Abuse Potential Study Of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users

NCT05614544
View directory record Official record
Conditions
General Anesthesia
Interventions
HSK3486, Propofol, Placebo
Drug
Lead sponsor
Haisco-USA Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 13, 2023 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Continuous Interscalene Block Results in Superior Recovery Throughout the First Postoperative Week

NCT01881776
View directory record Official record
Conditions
Postoperative Pain, Adverse Effects
Interventions
ISB
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 75 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2014 · Synced Oct 22, 2026, 7:28 PM EDT
Not listed No phase listed Observational

Cognitive Outcomes and Neuroimages Associated With Anesthesia-Related EEG Signatures

NCT03442179
View directory record Official record
Conditions
Elderly, General Anesthesia
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
65 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 22, 2026, 7:28 PM EDT
Completed No phase listed Observational

Electroencephalographic Changes Under General Anesthesia in Patients With Gynecologic Cancers With and Without History of Chemotherapy

NCT04593550
View directory record Official record
Conditions
Malignant Female Reproductive System Neoplasm
Interventions
Biospecimen Collection, BrainCheck Cognitive Assessment, Cognitive Assessment, Electroencephalography
Procedure · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
40 Years to 60 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Efficacy and Safety of HSK3486 Compared to Propofol in Induction of General Anesthesia in Adults Having Elective Surgery

NCT04711837
View directory record Official record
Conditions
Anesthesia
Interventions
HSK3486, Propofol
Drug
Lead sponsor
Haisco-USA Pharmaceuticals, Inc.
Industry
Eligibility
18 Years and older
Enrollment
255 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
13
States / cities
Phoenix, Arizona • Pasadena, California • Tamarac, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 22, 2026, 7:28 PM EDT
Withdrawn Phase 4 Interventional

GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture

NCT03226080
View directory record Official record
Conditions
Hip Fractures, Anesthesia, Spinal, Anesthesia, General, Neuromuscular Blockade
Interventions
Rocuronium, Sugammadex, Normal saline
Drug
Lead sponsor
Loyola University
Other
Eligibility
55 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Not applicable Interventional Results available

Regional Versus General Anesthesia for Promoting Independence After Hip Fracture

NCT02507505
View directory record Official record
Conditions
Hip Fractures
Interventions
Regional Anesthesia, General Anesthesia
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
1,848 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
38
States / cities
Birmingham, Alabama • Sacramento, California • Hartford, Connecticut + 31 more
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Oct 22, 2026, 7:28 PM EDT
Recruiting Not applicable Interventional

Prospective Randomized Observer Blinded Single Center Study Comparing 90-day Functional Outcome in Patients Who Received Intravenous Propofol Infusion Versus Inhalational Sevoflurane for General Anesthesia During Mechanical Thrombectomy in Patients Who Suffered From Acute Ischemic Stroke

NCT07001267
View directory record Official record
Conditions
Acute Ischemic Stroke Patients
Interventions
Anesthesia drugs during the surgery
Procedure
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 22, 2026, 7:28 PM EDT
Terminated Not applicable Interventional

Regional Anesthesia and Lung Cancer Recurrence

NCT01179308
View directory record Official record
Conditions
Lung Cancer
Interventions
General-epidural anesthesia, Balanced general anesthesia and postoperative opioids
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2016 · Synced Oct 22, 2026, 7:28 PM EDT
Active, not recruiting No phase listed Observational

Gastric Ultrasound in Pediatric Trauma Patients

NCT05330351
View directory record Official record
Conditions
Trauma; Complications, Aspiration
Interventions
Gastric Ultrasound
Diagnostic Test
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
0 Years to 17 Years
Enrollment
40 participants
Timeline
2022 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 22, 2026, 7:28 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Deflated and Inflated Cuff Endotracheal Extubations

NCT06990308
View directory record Official record
Conditions
Anesthesia Airway Management, Respiratory Complications
Interventions
Inflated Cuff Extubation, Deflated Cuff Extubation
Procedure
Lead sponsor
Naval Medical Center Camp Lejeune
Federal
Eligibility
18 Years to 50 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Marine Corps Base Camp Lejeune, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Phase 2 Interventional

A Randomized Study of the Efficacy of Low Venous Pressure General Anesthesia Versus Combined Spinal-Epidural Anesthesia in Decreasing Blood Loss During Prostate Surgery

NCT00200187
View directory record Official record
Conditions
Prostate Cancer
Interventions
low venous pressure general anesthesia, combined spinal-epidural anesthesia
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 26, 2007 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Not applicable Interventional Results available

Comparison of Different Ventilator and Vaporizer Technologies to Study Economic and Environmental Implications

NCT04851314
View directory record Official record
Conditions
Anesthetic Gas Consumption and Cost-Effectiveness
Interventions
ICU certified ventilator, Non-ICU certified ventilator
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2021 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Not applicable Interventional

Comparison of the Efficiency of Mouth-to-nose Breathing With Mouth-to-mouth Breathing

NCT00785447
View directory record Official record
Conditions
Cardiopulmonary Resuscitation, Respiratory Physiology
Interventions
Mouth-to-mouth or mouth-to-nose breathing
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 59 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 25, 2012 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Not applicable Interventional Results available

Effect of Location of Tetanic Stimuli on Photoplethysmogram

NCT03648853
View directory record Official record
Conditions
Stress Reaction
Interventions
Tetanic Stimulus
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 22, 2020 · Synced Oct 22, 2026, 7:28 PM EDT
Completed Not applicable Interventional

Lower Extremity Elevation to Minimize Hemodynamic Instability During Induction of General Anesthesia

NCT06513169
View directory record Official record
Conditions
Post Induction Hypotension
Interventions
Group 1: LEE
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 22, 2026, 7:28 PM EDT
Terminated Phase 4 Interventional

Cardiac and Renal Biomarkers in Arthroplasty Surgery

NCT03940651
View directory record Official record
Conditions
Renal Injury, Anesthesia, Myocardial Injury, Arthropathy of Knee, Arthropathy of Hip
Interventions
Spinal Anesthesia, General Anesthetics
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 5, 2021 · Synced Oct 22, 2026, 7:28 PM EDT