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ClinicalTrials.gov public records Last synced Sep 30, 2026, 7:26 PM EDT

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Showing 49–72 of 72 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anesthesia, Intravenous Clear all
Recruiting Phase 4 Interventional

A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements

NCT07552766
View directory record Official record
Conditions
Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified, Fracture Elbow, Fracture Fixation, Fracture Fixation, Internal, Fracture Forearm, Fracture Distal Radius
Interventions
Lidocaine Infusion, Standard of Care (SOC)
Drug · Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
3 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 30, 2026, 7:26 PM EDT
Terminated Not applicable Interventional Results available

Intravenous Sedation Versus General Anesthesia in Patients Undergoing Minor Gynecologic Surgery

NCT01890707
View directory record Official record
Conditions
Surgery, Anesthesia, Pain
Interventions
General Anesthesia, Deep Sedation
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 2, 2020 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections

NCT01734161
View directory record Official record
Conditions
Postoperative Nausea and Vomiting
Interventions
Dexamethasone, Placebo
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 46 Years · Female only
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Phase 4 Interventional

Effects of Desflurane and Propofol During Lung Volume Reduction Surgery

NCT04226625
View directory record Official record
Conditions
Lung Volume Reduction Surgery
Interventions
Propofol, Desflurane
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Sep 30, 2026, 7:26 PM EDT
Completed No phase listed Observational

Color Doppler and Peripheral Venous Catheters

NCT03889678
View directory record Official record
Conditions
Extravasation, Vein Injury
Interventions
Color flow doppler
Diagnostic Test
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Phase 3 Interventional

THRIVE Feasibility Trial

NCT05346588
View directory record Official record
Conditions
Surgery--Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia Emergence Delirium, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Nausea, Postoperative, Anesthesia Morbidity, Depression, Sleep Disorders, Circadian Rhythm
Interventions
Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Stanford, California • Ann Arbor, Michigan • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 24, 2023 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Total Intravenous Anesthesia in Sinus Surgery

NCT02578862
View directory record Official record
Conditions
Advanced Chronic Rhinosinusitis
Interventions
Propofol, Sevoflurane
Drug
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 21, 2018 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Phase 4 Interventional Results available

Analgesic Benefits of Perineural Versus Intravenous Dexamethasone in Patients Receiving Sciatic Nerve Block

NCT01616173
View directory record Official record
Conditions
Fracture of Ankle
Interventions
Dexamethasone, Saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 20, 2014 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Jet Lidocaine for Pain Relief During Needle Insertion in a Pediatric Emergency Department

NCT00681902
View directory record Official record
Conditions
Pain
Interventions
Lidocaine, Placebo
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
5 Years to 19 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2009 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation

NCT03255824
View directory record Official record
Conditions
Anesthesia
Interventions
Dexmedetomidine and Midazolam, Propofol, Midazolam, and Fentanyl
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 35 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Not applicable Interventional Results available

Anesthesia During Neurophysiologic Monitoring in Scoliosis Patients

NCT01549873
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
propofol, Desflurane
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 26, 2015 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Not applicable Interventional Results available

Does a Single Intravenous Dose of Ketamine Reduce the Need for Supplemental Opioids in Post-Cesarean Section Patients?

NCT00486902
View directory record Official record
Conditions
Ketamine Adverse Reaction, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy, Complication of Labor and/or Delivery
Interventions
Ketamine, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2014 · Synced Sep 30, 2026, 7:26 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Total Intravenous Anesthesia With Propofol vs. General Anesthesia in Outpatient Shoulder Arthroscopic Surgeries

NCT04793022
View directory record Official record
Conditions
Rotator Cuff Tears, Rotator Cuff Injuries, Orthopedic Disorder, Sports Injury, Anesthesia
Interventions
TIVA with Propofol, Inhaled Anesthesia
Drug
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Phase 4 Interventional Results available

Effect IV Ibuprofen and Inflammatory Responses

NCT01938040
View directory record Official record
Conditions
Gallbladder Disease
Interventions
ibuprofen, sugar water/placebo
Drug · Other
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years to 89 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
4
States / cities
Newark, New Jersey • Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 21, 2016 · Synced Sep 30, 2026, 7:26 PM EDT
Withdrawn Not applicable Interventional

Intravenous Anesthesia Versus Anesthesia With Volatile Agents in Elective Craniotomy for Tumors

NCT00555984
View directory record Official record
Conditions
Brain Neoplasms
Interventions
Propofol + Remifentanil, Sevoflurane + Remifentanil
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 20, 2017 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cataract Monitored Anesthesia Care (MAC) Feasibility Pilot Study

NCT06506669
View directory record Official record
Conditions
Cataract, Bilateral Senile Cataract, Anesthesia, Patient Satisfaction
Interventions
Oral sedation, Placebo
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 30, 2026, 7:26 PM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

EEG Study of IV Methylphenidate-Induced Emergence From Propofol Sedation

NCT03610282
View directory record Official record
Conditions
Anesthesia
Interventions
IV Methylphenidate, Propofol
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 21, 2020 · Synced Sep 30, 2026, 7:26 PM EDT
Terminated Not applicable Interventional

Determining if the Buzzy® Personal Pain Relief Device Reduces Injection Pain of Propofol as Much as Intravenous Lidocaine in Children

NCT07770581
View directory record Official record
Conditions
Propofol Injection Pain in Children
Interventions
Buzzy device, Intravenous lidocaine
Device · Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
12 Years to 17 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Sep 30, 2026, 7:26 PM EDT
Completed No phase listed Observational

Remifentanil Propofol Infusion in Pediatric Spinal Surgery

NCT00761072
View directory record Official record
Conditions
Spinal Fusion
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Day to 18 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 7, 2013 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Phase 2 Interventional Results available

Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures

NCT01516684
View directory record Official record
Conditions
Malignant Neoplasm
Interventions
placebo administration, EMLA, propofol, fentanyl citrate
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 22 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Sep 30, 2026, 7:26 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Investigating Near-Threshold Perception During Anesthetic Sedation

NCT06403852
View directory record Official record
Conditions
Propofol, Anesthesia, fMRI
Interventions
Functional Magnetic Resonance Imaging (fMRI) with propofol
Combination Product
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 40 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 30, 2026, 7:26 PM EDT
Terminated Phase 4 Interventional Results available

Multi-dose Acetaminophen for Patients Undergoing General Anesthesia

NCT02832687
View directory record Official record
Conditions
Recovery Following Cholecystectomy
Interventions
Acetaminophen, normal saline
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Newark, New Jersey • Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 30, 2026, 7:26 PM EDT
Terminated Phase 4 Interventional Results available

Comparative Study of Superficial Cervical Plexus Block and Nerve of Arnold Block and Incidence of PONV for Inner Ear Surgery

NCT02724033
View directory record Official record
Conditions
Anesthesia, Pediatrics, Surgery
Interventions
regional nerve block, Antiemetic
Procedure · Drug
Lead sponsor
Indiana University
Other
Eligibility
1 Year to 18 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 16, 2020 · Synced Sep 30, 2026, 7:26 PM EDT
Recruiting No phase listed Observational

Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients

NCT03431064
View directory record Official record
Conditions
Anesthesia, Intravenous Fluid, Blood Pressure
Interventions
Lung Recruitment Maneuver, Fluid Administration
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 17 Years
Enrollment
48 participants
Timeline
2018 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 30, 2026, 7:26 PM EDT