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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Anesthesia, Pediatric Clear all
Withdrawn No phase listed Observational Accepts healthy volunteers

Oxidative Stress in OR Personnel

NCT02654834
View directory record Official record
Conditions
Oxidative Stress
Interventions
Exposure to nitrous oxide or other volatile anesthetics
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Sep 25, 2026, 8:45 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Decreasing Emergence Delirium With Personalized Music

NCT06236477
View directory record Official record
Conditions
Emergence Delirium
Interventions
Personalized Music, No Music
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
3 Years to 9 Years
Enrollment
394 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 25, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Healthcare Provider Behavior and Children's Perioperative Distress

NCT01878747
View directory record Official record
Conditions
Pain, Postoperative, Infant Behavior
Interventions
Provider Tailored Intervention for Perioperative Stress
Behavioral
Lead sponsor
University of California, Irvine
Other
Eligibility
2 Years to 14 Years
Enrollment
1,471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
5
States / cities
Los Angeles, California • Menlo Park, California • Orange, California + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2019 · Synced Sep 25, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Use of an Adaptive Sensory Environment in Autism Spectrum Disorder (ASD) Patients in the Perioperative Environment

NCT04994613
View directory record Official record
Conditions
Autism Spectrum Disorder, Anesthesia, Procedural Anxiety, Sensory Processing Disorder
Interventions
Sensory adaptive environment
Other
Lead sponsor
Dayton Children's Hospital
Other
Eligibility
3 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Sep 25, 2026, 8:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Multi-center Isoelectric EEG Study in Children Under General Anesthesia

NCT03432351
View directory record Official record
Conditions
Electroencephalography, General Anesthesia, Pediatric Anesthesia
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Up to 36 Months
Enrollment
687 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
3
States / cities
Cincinnati, Ohio • Philadelphia, Pennsylvania • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 27, 2020 · Synced Sep 25, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Nasotracheal Intubation With VL vs DL in Infants Trial

NCT05433155
View directory record Official record
Conditions
Intubation Complication, Intubation; Difficult or Failed, Hypoxia, Hypoxemia, Anesthesia Intubation Complication, Pediatric HD
Interventions
Nasotracheal intubation
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Day to 365 Days
Enrollment
680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
8
States / cities
Aurora, Colorado • Washington D.C., District of Columbia • Philadelphia, Pennsylvania + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Sep 25, 2026, 8:45 PM EDT
Recruiting Phase 4 Interventional

Induction in the Dark

NCT06144177
View directory record Official record
Conditions
Anesthesia Induction
Interventions
Dark with star projector, Preoperative midazolam, Parental Presence
Other · Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
2 Years to 6 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 25, 2026, 8:45 PM EDT
Completed Not applicable Interventional

Virtual Parental Presence on Induction

NCT04574219
View directory record Official record
Conditions
Anxiety, Surgery
Interventions
Use of Facetime with child and parents during induction
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
4 Years to 12 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Sep 25, 2026, 8:45 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparison of Pain of Conventional to Buffered Local Anesthesia During Injection in Pediatric Dental Patients

NCT01622296
View directory record Official record
Conditions
Pain
Interventions
Sodium bicarbonate, Lidocaine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
9 Years to 12 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 16, 2014 · Synced Sep 25, 2026, 8:45 PM EDT
Withdrawn Phase 4 Interventional

Caudal vs. Pudendal Block in Peds GU

NCT05708989
View directory record Official record
Conditions
Hypospadias, Penile Torsion, Chordee, Phimosis
Interventions
Caudal Block, Ultrasound-guided Pudendal Block, Injectable 1 ml/kg of 0.25% ropivacaine with 1mcg/kg dexmedetomidine, Injection of 0.5 ml/kg per side of injectable 0.2-0.3% ropivacaine with 0.5 mcg/kg dexmetomedine.
Procedure · Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
6 Months to 3 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 25, 2024 · Synced Sep 25, 2026, 8:45 PM EDT
Completed No phase listed Observational

Society for Pediatric Anesthesia Improvement Network- Anterior Cruciate Ligament Reconstruction Outcomes Project

NCT04329117
View directory record Official record
Conditions
Anterior Cruciate Ligament Injuries
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 18 Years
Enrollment
526 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Boston, Massachusetts • Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Sep 25, 2026, 8:45 PM EDT
Completed No phase listed Observational

Review of Diagnostic Yield of MRI Brain Results in Children Under Age 3 Years

NCT03561168
View directory record Official record
Conditions
Seizures, Development Delay, Anesthetic Neurotoxicity
Interventions
Change in plan of care based on MRI results
Diagnostic Test
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 1095 Days
Enrollment
561 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Sep 25, 2026, 8:45 PM EDT
Completed No phase listed Observational

The Evaluation of a Noninvasive Respiratory Monitor in Pediatric Patients Undergoing General Anesthesia

NCT02336022
View directory record Official record
Conditions
Respiratory Complications
Interventions
Respiratory Motion Inc
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Year to 17 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 26, 2016 · Synced Sep 25, 2026, 8:45 PM EDT
Terminated Phase 2 Interventional Results available

Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Pediatric

NCT03962634
View directory record Official record
Conditions
Caries,Dental, Apical Periodontitis
Interventions
Kovanaze Nasal Spray, Articaine Injection
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
6 Years to 18 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Sep 25, 2026, 8:45 PM EDT
Completed Phase 2 Interventional Results available

Local Anesthetic Cream in Younger Patients Undergoing Lumbar Punctures

NCT01516684
View directory record Official record
Conditions
Malignant Neoplasm
Interventions
placebo administration, EMLA, propofol, fentanyl citrate
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 22 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 5, 2019 · Synced Sep 25, 2026, 8:45 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Effect of Dexmedetomidine on the Minimum Alveolar Concentration of Sevoflurane

NCT03384563
View directory record Official record
Conditions
Pediatric Anesthesia
Interventions
Dexmedetomidine
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
1 Month to 36 Months
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 25, 2026, 8:45 PM EDT
Recruiting Phase 4 Interventional

A Clinical Trial on the Use of Lidocaine Infusion During Surgery for Pediatric Upper Extremity Fractures and Its Impact on Total Perioperative Opioid Requirements

NCT07552766
View directory record Official record
Conditions
Fracture Arm, Fracture Closed of Lower End of Forearm, Unspecified, Fracture Elbow, Fracture Fixation, Fracture Fixation, Internal, Fracture Forearm, Fracture Distal Radius
Interventions
Lidocaine Infusion, Standard of Care (SOC)
Drug · Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
3 Years to 18 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 25, 2026, 8:45 PM EDT
Completed Not applicable Interventional Results available

Methadone in Pediatric Anesthesiology II

NCT01990573
View directory record Official record
Conditions
Pain
Interventions
0.3mg/kg IV methadone HCl, 0.4mg/kg IV methadon HCl, control no methadone
Drug · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
11 Years to 18 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Sep 25, 2026, 8:45 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Dose-Ranging Study of Intranasal Kovacaine Mist in Pediatric Subjects

NCT01701505
View directory record Official record
Conditions
Anesthesia
Interventions
400uL of Kovacaine Mist, 200uL of Kovacaine Mist, 120uL of Kovacaine Mist
Drug
Lead sponsor
St. Renatus, LLC
Industry
Eligibility
3 Years to 17 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 29, 2017 · Synced Sep 25, 2026, 8:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Photobiomodulation and Tooth Analgesia

NCT06691269
View directory record Official record
Conditions
Dental Anaesthesia, Dental Pain, Dental Analgesia
Interventions
Photobiomodulation, Topical Benzocaine, Local Anesthesia
Device · Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
6 Years to 12 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 25, 2026, 8:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Audiovisual Interactive Games to Alleviate Pediatric Perioperative Anxiety

NCT06111742
View directory record Official record
Conditions
Anxiety
Interventions
Bedside Entertainment and Relaxation Theater (BERT)
Device
Lead sponsor
Yale University
Other
Eligibility
4 Years to 14 Years
Enrollment
178 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 25, 2026, 8:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Extubation Criteria in Children With Upper Respiratory Infection (URI)

NCT04155892
View directory record Official record
Conditions
Upper Respiratory Tract Infections
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 7 Years
Enrollment
760 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 25, 2026, 8:45 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Childhood Anesthesia and Cognitive Function

NCT01359215
View directory record Official record
Conditions
Cognitive Deficits, Cognitive Ability, General
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
6 Years to 12 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
2
States / cities
Davis, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2013 · Synced Sep 25, 2026, 8:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Just-In-Time Rapid Cycle Deliberate Practice Simulation Intubation Training Among Novice Pediatric Anesthesia Trainees: A Randomized Control Study

NCT04472195
View directory record Official record
Conditions
Anesthesia
Interventions
Simulation Airway Coaching
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Not listed
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Sep 25, 2026, 8:45 PM EDT