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ClinicalTrials.gov public records Last synced Oct 19, 2026, 8:02 AM EDT

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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anesthesia; Functional Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers

Sevoflurane's Effect on Neurocognition Study

NCT06044740
View directory record Official record
Conditions
Anesthesia, Pain, Amnesia
Interventions
Sevoflurane, Peripheral Nerve Stimulation
Drug · Device
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years to 59 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 19, 2026, 8:02 AM EDT
Completed Not applicable Interventional Results available

Transcranial Electrostimulation and Obstructive Sleep Apnea Surgery

NCT03735004
View directory record Official record
Conditions
Transcranial Electrical Stimulation
Interventions
Transcranial electrostimulation (TES)
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 19, 2026, 8:02 AM EDT
Completed Not applicable Interventional

Music Distraction and Its Influence on Anesthetic Requirements During Elective Knee Surgery

NCT03486106
View directory record Official record
Conditions
Anesthesia; Functional, Surgery
Interventions
Music, Headphones, Propofol
Other · Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Oct 19, 2026, 8:02 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Transverse Abdominal Plane Anesthesia for Abdominal Wall Reconstruction

NCT02274077
View directory record Official record
Conditions
Hernia, Ventral
Interventions
EXPAREL, Normal Saline
Drug
Lead sponsor
Chester Mays
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 11, 2016 · Synced Oct 19, 2026, 8:02 AM EDT
Completed Phase 4 Interventional

Oral vs IV Sedation for Cataract Surgery in Older Adults

NCT07154147
View directory record Official record
Conditions
Cataract Surgery, Sedation, Cognition Function, Perioperative Care, Older Adults
Interventions
Alprazolam, Midazolam
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 19, 2026, 8:02 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Neural Correlates of Lidocaine Analgesia

NCT05501600
View directory record Official record
Conditions
Anesthesia, Pain
Interventions
Peripheral Nerve Stimulation, Lidocaine IV
Device · Drug
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 24, 2024 · Synced Oct 19, 2026, 8:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pre-op Use of Incentive Spirometry in Obese Patients

NCT01004146
View directory record Official record
Conditions
Lung Function, Bariatric Surgery
Interventions
Incentive Spirometry
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2014 · Synced Oct 19, 2026, 8:02 AM EDT
Completed Phase 4 Interventional Results available

Air-Q Intubating Laryngeal Airway Versus the Laryngeal Mask Airway (LMA)-Proseal

NCT01328405
View directory record Official record
Conditions
Difficult Airway, Anesthesia; Functional
Interventions
Laryngeal Mask Airway (LMA)
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 23, 2015 · Synced Oct 19, 2026, 8:02 AM EDT
Recruiting Not applicable Interventional

Prospective Randomized Observer Blinded Single Center Study Comparing 90-day Functional Outcome in Patients Who Received Intravenous Propofol Infusion Versus Inhalational Sevoflurane for General Anesthesia During Mechanical Thrombectomy in Patients Who Suffered From Acute Ischemic Stroke

NCT07001267
View directory record Official record
Conditions
Acute Ischemic Stroke Patients
Interventions
Anesthesia drugs during the surgery
Procedure
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 19, 2026, 8:02 AM EDT
Withdrawn Phase 3 Interventional

Effectiveness of Fascia Iliaca Nerve Block for Post Hip Arthroscopy

NCT02717728
View directory record Official record
Conditions
Hip Surgery Corrective, Anesthesia; Functional
Interventions
Drug group Fascia iliaca nerve block, Control group sham nerve block
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Years to 35 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 28, 2022 · Synced Oct 19, 2026, 8:02 AM EDT
Withdrawn Phase 4 Interventional

How Lidocaine Affects Outcomes In Orthopedic Surgery Patients

NCT01179100
View directory record Official record
Conditions
General Anesthesia, Surgeries Requiring A Minimum One Day Hospitalization, Elderly
Interventions
Lidocaine
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 7, 2015 · Synced Oct 19, 2026, 8:02 AM EDT
Completed No phase listed Observational

The Determination of the Effect of Volatile Anesthetics on Leukocyte Function ex Vivo

NCT02207842
View directory record Official record
Conditions
Leukocyte Function, Anesthesia
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
12 Months and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 1, 2017 · Synced Oct 19, 2026, 8:02 AM EDT
Withdrawn Phase 2 Interventional

Hemodynamic and Pharmacokinetic Analysis of Oxymetazoline Absorption

NCT02062996
View directory record Official record
Conditions
Dental Anesthesia, Nasal Surgical Procedures, Intranasal Drug Administration
Interventions
Oxymetazoline
Drug
Lead sponsor
Richard Cartabuke
Other
Eligibility
2 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 7, 2015 · Synced Oct 19, 2026, 8:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Restoration of Consciousness With Ultrasonic Deep Brain Stimulation During Anesthetic Sedation

NCT07221539
View directory record Official record
Conditions
Mental Function
Interventions
Propofol for fMRI, Dexmedetomidine for fMRI, Dorsolateral prefrontal cortex (DLPFC) pulsation, Anterior insular cortex (AIC) pulsation, Central thalamus (CT) pulsation
Procedure · Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 40 Years
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 19, 2026, 8:02 AM EDT
Completed No phase listed Observational

Hand Exercise and Upper Arm Anesthesia to Improvements Hand Function in Chronic Stroke Patients

NCT00006414
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 19, 2026, 8:02 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Nitrous Oxide Neuroimaging

NCT06702631
View directory record Official record
Conditions
Anesthesia, Pain, Amnesia
Interventions
Nitrous oxide, Peripheral Nerve Stimulation
Drug · Device
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years to 59 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 19, 2026, 8:02 AM EDT
Completed No phase listed Observational

Study of the Effect of Inhaled Anesthetics on Diastolic Heart Function Using a Doppler-derived Efficiency Index

NCT00907439
View directory record Official record
Conditions
Diastolic Dysfunction, Coronary Artery Disease, General Anesthesia
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 5, 2010 · Synced Oct 19, 2026, 8:02 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer

NCT05698576
View directory record Official record
Conditions
Prostate Cancer, Adverse Effects Surgery, MRI, Ultrasound, Sexual Function Disturbances, Urinary Incontinence, Urinary Function Disorders, Prostate Biopsy, Ablation
Interventions
TRANBERG® Transperineal Fusion Laser--Induced Thermal Therapy of Prostate Cancer (TPF-LITT)
Device
Lead sponsor
Urological Research Network, LLC
Other
Eligibility
50 Years to 80 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2033
U.S. locations
1
States / cities
Hialeah, Florida
Source: ClinicalTrials.gov public record
Updated Jan 26, 2023 · Synced Oct 19, 2026, 8:02 AM EDT
Completed No phase listed Observational

Optimizing Postoperative Cognition the Elderly

NCT02650687
View directory record Official record
Conditions
Postoperative Cognitive Dysfunction, POCD
Interventions
Processed EEG
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
65 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Oct 19, 2026, 8:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Functional Magnetic Resonance Imaging (fMRI) Findings in Children With Early Exposure to General Anesthesia

NCT01229514
View directory record Official record
Conditions
Exposed to Anesthesia
Interventions
fMRI
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
10 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 2, 2012 · Synced Oct 19, 2026, 8:02 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Anesthesia and Functional Connectivity: An Analysis of fMRI Changes

NCT02196259
View directory record Official record
Conditions
Changes in Brain Network Connectivity
Interventions
Anesthetics, Dissociative
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Oct 19, 2026, 8:02 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Remimazolam NeuroImaging

NCT07290205
View directory record Official record
Conditions
Anesthesia, Pain, Remimazolam
Interventions
Remimazolam, Peripheral Nerve Stimulation
Drug · Device
Lead sponsor
Keith M Vogt
Other
Eligibility
18 Years to 59 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 19, 2026, 8:02 AM EDT
Completed Not applicable Interventional Results available

Comparison of the ToFscan and TetraGraph During Recovery of Neuromuscular Function in the Post Anesthesia Care Unit

NCT03920670
View directory record Official record
Conditions
Residual Neuromuscular Blockade
Interventions
TetraGraph (TG), ToFscan (TS)
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Jacksonville, Florida • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Oct 19, 2026, 8:02 AM EDT
Completed Phase 4 Interventional Results available

Quality of Recovery After Reversal With Neostigmine or Sugammadex.

NCT02909439
View directory record Official record
Conditions
Incomplete Reversal of Neuromuscular Block
Interventions
Sugammadex, Neostigmine
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 99 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated May 22, 2020 · Synced Oct 19, 2026, 8:02 AM EDT