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ClinicalTrials.gov public records Last synced Oct 6, 2026, 7:57 PM EDT

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Showing 121–144 of 183 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anesthesia , Analgesia Clear all
Recruiting Phase 1 Interventional

Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau

NCT06639503
View directory record Official record
Conditions
Tibial Plateau Fractures
Interventions
Bupivacain
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 6, 2026, 7:57 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Laparoscopic Assisted Plane Block (LAPB) Trial

NCT03730402
View directory record Official record
Conditions
Opioid Use
Interventions
Bupivacaine, Exparel 266 milligram Per 20 ML Injection, Saline
Drug
Lead sponsor
Santa Barbara Cottage Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Santa Barbara, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Oct 6, 2026, 7:57 PM EDT
Terminated Phase 4 Interventional Results available

Erector Spinae Plane Block (ESPB): in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.

NCT03691935
View directory record Official record
Conditions
Nephrectomy, Partial Nephrectomy, Incision Site Discomfort
Interventions
Ropivacaine, Normal saline
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 6, 2026, 7:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Patient Preferences in Anesthesia for Abortion Care

NCT03030443
View directory record Official record
Conditions
Pregnancy Termination in First Trimester
Interventions
Not listed
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 31, 2023 · Synced Oct 6, 2026, 7:57 PM EDT
Not yet recruiting Not applicable Interventional

Quadratus Lumborum Versus Placebo in Open Ventral Hernia Repair

NCT06953635
View directory record Official record
Conditions
Hernia, Ventral, Pain Management
Interventions
Quadratus Lumborum (QL) Block, Placebo
Procedure
Lead sponsor
University of Tennessee Graduate School of Medicine
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 1, 2025 · Synced Oct 6, 2026, 7:57 PM EDT
Completed Not applicable Interventional Results available

Nurse Initiated Acupressure for Pain Management

NCT04044716
View directory record Official record
Conditions
Pain, Postoperative, Pain, Acute
Interventions
Auricular acupressure, Standard of care pain management
Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Bermuda Run, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 7, 2022 · Synced Oct 6, 2026, 7:57 PM EDT
Completed No phase listed Observational

ADVANCE: Assessment for Defining Variability in Anesthesia Through Novel Clinical EEG

NCT00689130
View directory record Official record
Conditions
Pain
Interventions
Not listed
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
3
States / cities
Atlanta, Georgia • Louisville, Kentucky • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2012 · Synced Oct 6, 2026, 7:57 PM EDT
Withdrawn Phase 3 Interventional

Multimodal Analgesia in Shoulder Arthroplasty

NCT03586934
View directory record Official record
Conditions
Shoulder Pain, Opioid Use
Interventions
Acetaminophen, Celecoxib 200mg, Celecoxib 400 mg, Ropivacaine, Ketorolac, Acetaminophen Injectable Product, Oxycodone, Tramadol, Morphine Injectable Solution, hydrocodone bitartrate and acetaminophen, Morphine, Oxycodone Hydrochloride, Meloxicam
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 6, 2026, 7:57 PM EDT
Terminated Phase 4 Interventional Results available

Success of External Cephalic Version Study

NCT03106753
View directory record Official record
Conditions
External Cephalic Version
Interventions
Bupivacaine, Terbutaline
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 9, 2020 · Synced Oct 6, 2026, 7:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Regional Anesthesia (Supra-Orbital and Infra-Orbital Nerve Block) (SION) for Pain Management in Trans-sphenoidal Hypophysectomy

NCT04670614
View directory record Official record
Conditions
Post-operative Surgical Pain
Interventions
Nerve Block with ropivicaine 0.5% Injectable Solution, Nerve Block with Placebo sham control of 0.9% Normal Saline
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2020 · Synced Oct 6, 2026, 7:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

SZMN Blocks for Pain Control in Pediatric Patients Undergoing T&A

NCT04797559
View directory record Official record
Conditions
Postoperative Pain, Opioid Use
Interventions
SZMN Block
Procedure
Lead sponsor
Stanford University
Other
Eligibility
6 Months to 18 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 6, 2026, 7:57 PM EDT
Terminated Not applicable Interventional Results available

Preemptive Femoral & Lateral Femoral Cutaneous Nerve Blocks for THA Acute Pain

NCT01997567
View directory record Official record
Conditions
Internal Derangement of Hip, Acetabular Labrum Tear
Interventions
Ropivacaine, Placebo
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Oak Park, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Oct 6, 2026, 7:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Transversus Abdominis Plane (TAP) Block Techniques: Surgeon vs Anesthesia - Ultrasound Guidance

NCT03577912
View directory record Official record
Conditions
Post Operative Analgesia, Non-inferiority Trial
Interventions
TAP block administered by Surgery, TAP block administered by Anesthesia
Procedure
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Oct 6, 2026, 7:57 PM EDT
Completed Not applicable Interventional

Combination Ketamine and Propofol vs Propofol for Emergency Department Sedation: A Prospective Randomized Trial

NCT01269307
View directory record Official record
Conditions
Sedation
Interventions
1:1 ketamine-propofol mixture sedation, Propofol Sedation
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 12, 2014 · Synced Oct 6, 2026, 7:57 PM EDT
Completed Phase 4 Interventional Results available

Effect of Fentanyl on Coughing and Recovery After Anesthesia With an LMA Laryngeal Mask Airway)for Airway Management

NCT01368809
View directory record Official record
Conditions
Ambulatory Surgery, Coughing
Interventions
Saline, Fentanyl
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2016 · Synced Oct 6, 2026, 7:57 PM EDT
Completed Not applicable Interventional Results available

Comparison of Pre-op and Post-op Pectoralis Nerve Block

NCT03653988
View directory record Official record
Conditions
Breast Cancer, Postoperative Pain, Anesthesia, Nerve Block
Interventions
PEC I/II blocks by anesthesiologist - pre-operative, PEC I/II blocks by surgeon - intra-operative
Procedure
Lead sponsor
Melinda Seering
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 16, 2024 · Synced Oct 6, 2026, 7:57 PM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Parturient Controlled Epidural Analgesia (PCEA) With or Without a Basal Infusion for Early Labor

NCT00871442
View directory record Official record
Conditions
Labor Pain
Interventions
No Basal Infusion, Basal infusion, PCEA solution (bupivacaine and fentanyl)
Other · Drug
Lead sponsor
Neil Roy Connelly, MD
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 18, 2015 · Synced Oct 6, 2026, 7:57 PM EDT
Terminated Phase 4 Interventional

Use of Long-acting Bupivacaine In Lower Extremity Amputation

NCT04360421
View directory record Official record
Conditions
Amputation, Anesthesia, Local, Opioid Use
Interventions
Liposomal bupivacaine
Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Oct 6, 2026, 7:57 PM EDT
Completed Phase 2 Interventional

Rofecoxib and Bupivacaine to Prevent Pain After Third Molar (Wisdom Tooth) Extraction

NCT00050362
View directory record Official record
Conditions
Pain, Tooth Extraction
Interventions
Rofecoxib and Bupivacaine
Drug
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 6, 2026, 7:57 PM EDT
Enrolling by invitation No phase listed Observational

Characterizing the EEG Signature of Fentanyl and Its Association With Drug Liking

NCT06699953
View directory record Official record
Conditions
Brain Activity Related to Opioid Administration, Brain Activity Related to Drug Liking
Interventions
Observational study in patients receiving fentanyl for surgery
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 6, 2026, 7:57 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties

NCT05868330
View directory record Official record
Conditions
Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
Interventions
Interscalene Catheter, Exparel Single Shot Interscalene Block
Procedure
Lead sponsor
Melinda Seering
Other
Eligibility
18 Years to 90 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 6, 2026, 7:57 PM EDT
Completed Phase 3 Interventional Results available

Regional Anesthesia and Breast Cancer Recurrence

NCT00418457
View directory record Official record
Conditions
Breast Neoplasms
Interventions
General anesthesia and opioids, Regional analgesia and propofol
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
2,108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 16, 2020 · Synced Oct 6, 2026, 7:57 PM EDT
Completed Not applicable Interventional

The Effect of a Culturally Sensitive Educational Intervention on Acceptance of Neuraxial Anesthesia

NCT02672397
View directory record Official record
Conditions
Labor Pain
Interventions
Additional Epidural Education
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 6, 2026, 7:57 PM EDT
Not yet recruiting Phase 4 Interventional

IPP Placement & Intracavernosal Block

NCT07246642
View directory record Official record
Conditions
Erectile Dysfunction (ED)
Interventions
Exparel/bupivacaine mixture
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older · Male only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 6, 2026, 7:57 PM EDT