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ClinicalTrials.gov public records Last synced Oct 2, 2026, 5:59 AM EDT

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Showing 49–72 of 164 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Anesthesia and Analgesia Clear all
Terminated Not applicable Interventional Results available

The Optimal Dosage of Intrathecal Morphine for Peripartum Analgesia

NCT01146457
View directory record Official record
Conditions
Labor Pain
Interventions
Morphine, Saline
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Oct 2, 2026, 5:59 AM EDT
Completed Early Phase 1 Interventional

Erector Spinae Regional Anesthesia for Pain Control

NCT05794828
View directory record Official record
Conditions
Pain Management
Interventions
Bupivacaine Injection
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Ridley Park, Pennsylvania • Upland, Pennsylvania • San Antonio, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Oct 2, 2026, 5:59 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

EpiFaith Resident Learning Curve Trial

NCT07395622
View directory record Official record
Conditions
Epidural Analgesia, Epidural Analgesia for Labour and Delivery, Learning Curve
Interventions
EpiFaith epidural syringe, Control (glass) syringe
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 2, 2026, 5:59 AM EDT
Completed Phase 2 Interventional Results available

Great Auricular Nerve Block for Children Undergoing Tympanomastoid Surgery

NCT01638052
View directory record Official record
Conditions
Tympanomastoid Surgery, Cochlear Implant, Mastoidectomy, Cholesteatoma
Interventions
0.25% Bupivacaine + Clonidine
Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
1 Year to 18 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 4, 2021 · Synced Oct 2, 2026, 5:59 AM EDT
Terminated Phase 4 Interventional Results available

Exparel vs. Standard Bupivicaine for Abdominoplasty

NCT01853176
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Liposomal Injection Bupivacaine (Exparel), Standard bupivicaine
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 3, 2014 · Synced Oct 2, 2026, 5:59 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Study to Compare Reduction in Pain After Surgery With and Without Local Anesthesia During Laparoscopy

NCT01452633
View directory record Official record
Conditions
Post Operative Pain
Interventions
0.25% bupivicaine will be injected at the study port site prior to incision, Saline will be injected at the study port site prior to incision, Saline will be in injected into the port site prior to closure, 0.25% bupivicaine will be injected into the port site prior to closure
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
21 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2013 · Synced Oct 2, 2026, 5:59 AM EDT
Completed No phase listed Observational

Chloroprocaine for Continuous Epidural Analgesia in Neonates and Infants

NCT02207855
View directory record Official record
Conditions
Anesthesia
Interventions
Chloroprocaine
Drug
Lead sponsor
Joseph D. Tobias
Other
Eligibility
Up to 2 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 29, 2016 · Synced Oct 2, 2026, 5:59 AM EDT
Completed Not applicable Interventional Results available

Adductor Canal Block for Total Knee Arthroplasty

NCT02453360
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee, Pain, Postoperative
Interventions
Adductor Canal Block, Adductor Canal Block
Procedure · Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 8, 2019 · Synced Oct 2, 2026, 5:59 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Epidural Anesthesia /Analgesia Versus PCA for Laparoscopic Complex Ventral Hernia Repair: A Randomized Controlled Trial

NCT00529074
View directory record Official record
Conditions
Analgesia
Interventions
Epidural Catheter for Analgesia
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 16, 2016 · Synced Oct 2, 2026, 5:59 AM EDT
Terminated Not applicable Interventional Results available

Combined Spinal Epidural Urinary Retention

NCT01597791
View directory record Official record
Conditions
Anesthesia, Pain, Urinary Retention
Interventions
Foley catheter, No foley catheter
Device · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 5, 2018 · Synced Oct 2, 2026, 5:59 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients

NCT01982838
View directory record Official record
Conditions
Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
Interventions
Epidural de novo, CSE
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 11, 2014 · Synced Oct 2, 2026, 5:59 AM EDT
Completed Not applicable Interventional

The Effect of a Culturally Sensitive Educational Intervention on Acceptance of Neuraxial Anesthesia

NCT02672397
View directory record Official record
Conditions
Labor Pain
Interventions
Additional Epidural Education
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 4, 2020 · Synced Oct 2, 2026, 5:59 AM EDT
Enrolling by invitation Phase 3 Interventional Accepts healthy volunteers

RCT to Test Regional Anesthesia Effect on Decreased Opiate Use

NCT06989866
View directory record Official record
Conditions
Postoperative Pain
Interventions
Bupivacaine, Saline (NaCl 0,9 %) (placebo)
Drug
Lead sponsor
United States Naval Medical Center, Portsmouth
Federal
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Oct 2, 2026, 5:59 AM EDT
Completed Not applicable Interventional Results available

Motor-Sparing Peripheral Nerve Blockade Facilitates Mobility Post Total Knee Arthroplasty: A Randomized Controlled Trial

NCT02773537
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee
Interventions
Femoral nerve catheter and sciatic nerve block, Adductor canal catheter and selective tibial block, Adductor canal catheter only
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 27, 2019 · Synced Oct 2, 2026, 5:59 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Regional Anesthesia Following Pediatric Cardiac Surgery

NCT05688670
View directory record Official record
Conditions
Atrial Septal Defect, Ventricular Septal Defect, Pain, Procedural
Interventions
Regional Anesthesia, Wound infiltration, Ropivacaine 0.2% Injectable Solution
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
Up to 17 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Oct 2, 2026, 5:59 AM EDT
Completed No phase listed Observational

Comparison of Epidural and TAP Block in Abdominal Surgery

NCT01848951
View directory record Official record
Conditions
Acute Pain, Surgery, Regional Anesthesia
Interventions
Epidural, TAP Block
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Oct 2, 2026, 5:59 AM EDT
Completed Not applicable Interventional Results available

A Pain Study Comparing Two Commonly Used Medications to Treat Pain After Bowel Surgery

NCT02849678
View directory record Official record
Conditions
Postoperative Pain
Interventions
Ropivacaine, Lidocaine
Drug
Lead sponsor
Jacques E. Chelly
Other
Eligibility
18 Years to 80 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Oct 2, 2026, 5:59 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Empathy Through Pain Control: Lidocaine Paracervical Block for IUD Placements

NCT06960317
View directory record Official record
Conditions
Contraception, Pain, Acute, Anesthesia, Local
Interventions
Buffered Lidocaine, Sham Comparator, Unbuffered lidocaine, Xylocaine jelly 2%, Surgilube
Drug · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
204 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2025 · Synced Oct 2, 2026, 5:59 AM EDT
Completed Not applicable Interventional

Pain Management After TKA: Comparison of Short- and Long-term Nerve Blocks

NCT03245359
View directory record Official record
Conditions
Anesthesia, Local, Pain, Postoperative
Interventions
Short-term ON-Q, Short-term ON-Q, Long-term ON-Q, Long-term ON-Q
Device · Drug
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 2, 2019 · Synced Oct 2, 2026, 5:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ultrasound Guided Posterior Quadratus Lumborum Block for Postoperative Analgesia in Gynecologic Surgery

NCT04549090
View directory record Official record
Conditions
Post-operative Pain, Gynecologic Surgery, Regional Anesthesia
Interventions
QL (quadratus lumborum) block administration
Drug
Lead sponsor
Pedram Bral
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Oct 2, 2026, 5:59 AM EDT
Withdrawn Not applicable Interventional

Clinical Evaluation of the Ultrasound-Guided Retroclavicular Brachial Plexus Block

NCT01605929
View directory record Official record
Conditions
Anesthesia, Upper Extremity Injury
Interventions
Retroclavicular Brachial Plexus Block and Catheter Insertion
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 7, 2015 · Synced Oct 2, 2026, 5:59 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Pupillometry in Identifying Risk of Postoperative Opioid-induced Respiratory Depression in Children Undergoing Tonsillectomy

NCT07573150
View directory record Official record
Conditions
Opioid-Induced Respiratory Depression, Postoperative Complications (Cardiopulmonary), Respiratory Complications Due to Anesthesia
Interventions
Infrared Pupillometry
Device
Lead sponsor
NeurOptics Inc
Industry
Eligibility
3 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
San Francisco, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 2, 2026, 5:59 AM EDT
Completed No phase listed Observational

Medical Review: Hand Surgery After Local Block Versus Non-block

NCT01110759
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Not listed
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2013 · Synced Oct 2, 2026, 5:59 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural

NCT05514431
View directory record Official record
Conditions
Anesthesia, Analgesia
Interventions
Epidural, Dural Puncture Epidural (DPE) technique, Combined Spinal-Epidural (CSE) technique
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
Female only
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 2, 2026, 5:59 AM EDT