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Showing 1–24 of 159 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Airway Complication of Anesthesia
Interventions
Advanced airway management
Procedure
Lead sponsor
University of Turin, Italy
Other
Eligibility
18 Years and older
Enrollment
10,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Dallas, Texas • Houston, Texas
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects

NCT01557920
Conditions
Airway Complication of Anaesthesia, Healthy
Interventions
Propofol, Sevoflurane
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Anesthesia, General, Surgical Oncology
Interventions
Propofol, Volatile Agent
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
1,826 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
5
States / cities
Buffalo, New York • New Hyde Park, New York • New York, New York + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery

NCT00380978
Conditions
Labor Pain, Pregnancy
Interventions
combined spinal epidural analgesia, late analgesia (systemic)
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,026 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Anesthesia, Upper Extremity Injury
Interventions
Retroclavicular Brachial Plexus Block and Catheter Insertion
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Wellness, Self Compassion, Burnout, Anxiety, Depression
Interventions
App-based bundled mental fitness intervention, App-based wellness module collection
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Intravenous Anesthetics on Fear Learning and Memory

NCT00767767
Conditions
Phobias
Interventions
Placebos, Propofol 0.45mcg/mL, Propofol 0.90mcg/mL, Thiopental 1.5mcg/mL, Thiopental 3mcg/mL
Drug
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 50 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Perioperative Audio for Anaesthesia

NCT05291832
Conditions
Anesthesia
Interventions
Brain.fm Music, Spectrally-matched Noise
Other
Lead sponsor
Brain.fm, Inc.
Industry
Eligibility
Not listed
Enrollment
329 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Plano, Texas
Conditions
Complications; Cesarean Section, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Interventions
Phenylephrine
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Endotracheal Extubation, Airway Anesthesia, Paediatric
Interventions
Direct removal of endotracheal tube, Laryngeal mask airway inserted following deep extubation
Procedure
Lead sponsor
Telethon Kids Institute
Other
Eligibility
0 Years to 16 Years
Enrollment
1,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Philadelphia, Pennsylvania
Conditions
Pain
Interventions
Ofirmev, Caldolor
Drug
Lead sponsor
Anita Gupta
Other
Eligibility
18 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Airway Reflexes, Protective, Recovery After Neuromuscular Block, Anesthetic Recovery
Interventions
Sevoflurane, Desflurane, Rocuronium, Neostigmine, Glycopyrrolate
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
San Francisco, California
Conditions
Diastolic Dysfunction, Coronary Artery Disease, General Anesthesia
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Adverse Effect of Unspecified General Anesthetics
Interventions
Supreme Laryngeal mask airway, Proseal laryngeal mask airway
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Pain
Interventions
Vitrase (ovine hyaluronidase) Lyophilized
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Maternal Anaesthesia and Analgesia Affecting Fetus or Newborn, Breast Feeding, Fentanyl, Bupivacaine, Nalbuphine
Interventions
Not listed
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Phase 4 Interventional Results available

Effect of Ketorolac on Post Adenotonsillectomy Pain

NCT03467750
Conditions
Obstructive Sleep Apnea
Interventions
Ketorolac, Standard of Care
Drug
Lead sponsor
Emory University
Other
Eligibility
2 Years to 18 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Completed Phase 1 Interventional Accepts healthy volunteers

Safety Study of Long-Acting Local Anesthetic

NCT01786655
Conditions
Safety of Neosaxitoxin in Healthy Volunteers
Interventions
Neosaxitoxin in saline, NeoSTX + bupivacaine 0.2%, NeoSTX + bupivacaine 0.2% + epinephrine 5mcg/ml, Saline placebo
Drug · Other
Lead sponsor
Charles Berde
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

RHA® Redensity With New Anesthetic Agent - Perioral Rhytids

NCT04069585
Conditions
Aging, Pain
Interventions
RHA® Redensity with new anesthetic agent, RHA® Redensity with lidocaine
Device
Lead sponsor
Teoxane SA
Industry
Eligibility
22 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
3
States / cities
Beverly Hills, California • Coral Gables, Florida • Chicago, Illinois
Conditions
Liver Transplantation
Interventions
Methadone, ketamine, Hydromorphone, fentanyl
Drug
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Burlington, Massachusetts
Conditions
Septic Shock, Sepsis, Shock
Interventions
Not listed
Lead sponsor
Albany Medical College
Other
Eligibility
Not listed
Enrollment
50 participants
Timeline
2025 – 2027
U.S. locations
1
States / cities
Albany, New York
Not listed Phase 2 Interventional Accepts healthy volunteers

Pain After Buffered Vs Non Buffered Articaine

NCT06538233
Conditions
Pain
Interventions
Buffered articaine, Non buffered articaine
Drug
Lead sponsor
Cleveland Dental Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Not listed Phase 4 Interventional Accepts healthy volunteers

Comparative Efficacy of 20% Benzocaine Versus TAC Alternate Gel

NCT00846690
Conditions
Dental Pain, Postoperative Pain
Interventions
benzocaine, TAC alternate gel
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
6655 Travis Suite 460, Texas
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis

NCT01951820
Conditions
Anesthesia of Mucous Membrane
Interventions
Pliaglis, Benzocaine, Articaine
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan