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Showing 25–41 of 17 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Anesthetics, General Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects

NCT01557920
View directory record Official record
Conditions
Airway Complication of Anaesthesia, Healthy
Interventions
Propofol, Sevoflurane
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 12, 2016 · Synced Sep 17, 2026, 7:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Assess Indices of SNAP vs VISTA on Surgical Patients Undergoing General Anesthesia

NCT00829803
View directory record Official record
Conditions
Anesthesia, General
Interventions
SNAP monitor; Bispectral Index Monitor (BIS Monitor)
Device
Lead sponsor
Stryker Instruments
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
4
States / cities
Miami, Florida • Chicago, Illinois • Royal Oak, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Sep 17, 2026, 7:43 AM EDT
Completed No phase listed Observational

Provider Variability in the Use of Neuromuscular Blocking Drugs and Reversal

NCT03585348
View directory record Official record
Conditions
Neuromuscular Blockade, Residual Curarisation, Postoperative, Surgery Under General Anaesthesia
Interventions
Neuromuscular blocking agents
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
265,537 participants
Timeline
2018 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 24, 2021 · Synced Sep 17, 2026, 7:43 AM EDT
Completed No phase listed Observational

Cocaine Use and Outcomes of General Anesthesia

NCT02692534
View directory record Official record
Conditions
Anesthesia
Interventions
Urine cocaine negative, Urine cocaine positive
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Sep 17, 2026, 7:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Intrathecal Local Anesthetics on Left Ventricular Global Longitudinal Strain

NCT05650008
View directory record Official record
Conditions
Left Ventricular Dysfunction, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Global Cardiac Wall Motion Dysfunction
Interventions
Intrathecal local anesthesia
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2023 · Synced Sep 17, 2026, 7:43 AM EDT
Not listed No phase listed Observational

Tau/P-Tau and Neurocognitive Outcomes in Children

NCT03511729
View directory record Official record
Conditions
General Anesthetics Toxicity, Postoperative Cognitive Dysfunction, Child Development
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
3 Years to 5 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Sep 17, 2026, 7:43 AM EDT
Not listed No phase listed Observational

A Prospective Study to Bilaterally Compare a Non-Invasive Cardiac Output Monitor

NCT01678066
View directory record Official record
Conditions
Anesthesiology, Pediatrics, General Surgery, Orthopedics, General Anesthesia, Cardiac Output
Interventions
Bilateral cardiac output
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
1 Month to 8 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2012 · Synced Sep 17, 2026, 7:43 AM EDT
Completed No phase listed Observational Results available

Sevoflurane Concentrations in Children

NCT06510803
View directory record Official record
Conditions
Anesthetic, Sevoflurane, Age
Interventions
The washin of sevoflurane in the GE Ohmeda workstation
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
2 Years to 7 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 17, 2026, 7:43 AM EDT
Completed Phase 4 Interventional

General Anesthetics in CAncer REsection Surgery (GA-CARES) Trial

NCT03034096
View directory record Official record
Conditions
Anesthesia, General, Surgical Oncology
Interventions
Propofol, Volatile Agent
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
1,826 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
5
States / cities
Buffalo, New York • New Hyde Park, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Sep 17, 2026, 7:43 AM EDT
Withdrawn Not applicable Interventional

The BALANCED Anaesthesia Study

NCT02073357
View directory record Official record
Conditions
Effect of General Anesthetic Dose on Recovery From Surgery
Interventions
Light general anaesthesia (BIS = 50), deep general anaesthesia (BIS = 35)
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
60 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 30, 2014 · Synced Sep 17, 2026, 7:43 AM EDT
Recruiting No phase listed Observational

Natural History of Depression, Bipolar Disorder and Suicide Risk

NCT06462196
View directory record Official record
Conditions
Behavioral Symptoms, Suicide, Self-Injurious Behavior, Sensory System Agents, Analgesics, Peripheral Nervous System Agents, Physiological Effects of Drugs, Anesthetics, Dissociative, Anesthetics, General, Anesthetics, Central Nervous System Depressants, Excitatory Amino Acid Antagonists, Excitatory Amino Acid Agents, Neurotransmitter Agents, Molecular Mechanisms of Pharmacological Action, Ketamine, Depression, Unipolar, Depressive Symptoms, Treatment Resistant Depression, Major Depressive Disorder, Depression, Bipolar
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 120 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 17, 2026, 7:43 AM EDT
Completed No phase listed Observational

The Hypotensive Effect of Propofol: an Observational Study

NCT01508351
View directory record Official record
Conditions
Hypotension, Anesthesia
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Sep 17, 2026, 7:43 AM EDT
Completed Not applicable Interventional Results available

Comparison of Different Ventilator and Vaporizer Technologies to Study Economic and Environmental Implications

NCT04851314
View directory record Official record
Conditions
Anesthetic Gas Consumption and Cost-Effectiveness
Interventions
ICU certified ventilator, Non-ICU certified ventilator
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 65 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Sep 17, 2026, 7:43 AM EDT
Completed Not applicable Interventional Results available

Addition of Nitrous Oxide and Its Effects on Depth of Anesthesia

NCT00717574
View directory record Official record
Conditions
Deep Sedation, Anesthesia, General
Interventions
Sevoflurane group, Propofol group
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Sep 17, 2026, 7:43 AM EDT
Withdrawn Phase 4 Interventional

How Lidocaine Affects Outcomes In Orthopedic Surgery Patients

NCT01179100
View directory record Official record
Conditions
General Anesthesia, Surgeries Requiring A Minimum One Day Hospitalization, Elderly
Interventions
Lidocaine
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 6, 2015 · Synced Sep 17, 2026, 7:43 AM EDT
Completed No phase listed Observational

Neurodegeneration in Newborns After Anesthetics

NCT03064607
View directory record Official record
Conditions
Neurodegeneration, General Anesthesia
Interventions
Fluid collection
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2019 · Synced Sep 17, 2026, 7:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparative Effects of Two Anesthetic Techniques on Auditory Brain Response in Children

NCT02830815
View directory record Official record
Conditions
Auditory Brainstem Response
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 18 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Sep 17, 2026, 7:43 AM EDT