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Showing 25–40 of 16 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Anesthetics, General Clear all
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Comparing Desflurane to Sevoflurane for the Effect on Recovery Time in Patients Undergoing Urological Cystoscope Surgery

NCT01219881
View directory record Official record
Conditions
Cystoscopes, Baxter Anaesthesia Brand of Desflurane, Sevoflurane
Interventions
Desflurane, Sevoflurane
Drug
Lead sponsor
Ohio State University
Other
Eligibility
50 Years to 75 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 15, 2021 · Synced Jun 27, 2026, 5:48 AM EDT
Withdrawn Not applicable Interventional

The BALANCED Anaesthesia Study

NCT02073357
View directory record Official record
Conditions
Effect of General Anesthetic Dose on Recovery From Surgery
Interventions
Light general anaesthesia (BIS = 50), deep general anaesthesia (BIS = 35)
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
60 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 30, 2014 · Synced Jun 27, 2026, 5:48 AM EDT
Recruiting Phase 4 Interventional

Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia

NCT07348614
View directory record Official record
Conditions
Knee Stiffness After Total Knee Arthroplasty
Interventions
Spinal Anesthesia, General Anesthesia, Propofol, Chloroprocaine
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 75 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 27, 2026, 5:48 AM EDT
Completed Phase 4 Interventional Results available

Comparison of ProSeal Laryngeal Mask Airway to Laryngeal Mask Airway Supreme

NCT00836095
View directory record Official record
Conditions
Adverse Effect of Unspecified General Anesthetics
Interventions
Supreme Laryngeal mask airway, Proseal laryngeal mask airway
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Jun 27, 2026, 5:48 AM EDT
Completed No phase listed Observational

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

NCT01431326
View directory record Official record
Conditions
Adenovirus, Anesthesia, Anxiety, Anxiolysis, Autism, Autistic Disorder, Bacterial Meningitis, Bacterial Septicemia, Benzodiazepine, Bipolar Disorder, Bone and Joint Infections, Central Nervous System Infections, Convulsions, Cytomegalovirus Retinitis, Early-onset Schizophrenia Spectrum Disorders, Epilepsy, General Anesthesia, Gynecologic Infections, Herpes Simplex Virus, Infantile Hemangioma, Infection, Inflammation, Inflammatory Conditions, Intra-abdominal Infections, Lower Respiratory Tract Infections, Migraines, Pain, Pneumonia, Schizophrenia, Sedation, Seizures, Skeletal Muscle Spasms, Skin and Skin-structure Infections, Treatment-resistant Schizophrenia, Urinary Tract Infections, Withdrawal, Sepsis, Gram-negative Infection, Bradycardia, Cardiac Arrest, Cardiac Arrhythmia, Staphylococcal Infections, Nosocomial Pneumonia, Neuromuscular Blockade, Methicillin Resistant Staphylococcus Aureus, Endocarditis, Neutropenia, Headache, Fibrinolytic Bleeding, Pulmonary Arterial Hypertension, CMV Retinitis, Hypertension, Chronic Kidney Diseases, Hyperaldosteronism, Hypokalemia, Heart Failure, Hemophilia, Heavy Menstrual Bleeding, Insomnia
Interventions
The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
Drug
Lead sponsor
Daniel Benjamin
Other
Eligibility
Up to 21 Years
Enrollment
3,520 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
43
States / cities
Anchorage, Alaska • Little Rock, Arkansas • La Jolla, California + 37 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Jun 27, 2026, 5:48 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans

NCT04032301
View directory record Official record
Conditions
Post-Traumatic Stress Disorders, Major Depressive Disorder
Interventions
Ketamine, Normal Saline
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 75 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Jun 27, 2026, 5:48 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Repeated Neurocognitive Measurements in Depressed Patients

NCT05991232
View directory record Official record
Conditions
Depression, Unipolar
Interventions
Intravenous Ketamine
Drug
Lead sponsor
Jay Fournier
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Jun 27, 2026, 5:48 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Isoflurane at Subanesthetic Concentrations - 6

NCT00000254
View directory record Official record
Conditions
Opioid-Related Disorders, Substance-Related Disorders
Interventions
40% Nitrous oxide, Sham comparator, 0.2% isoflurane, 0.4% isoflurane, 0.6% isoflurane
Drug · Other
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 34 Years · Male only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1995
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Jun 27, 2026, 5:48 AM EDT
Completed Phase 2 Interventional

Nitrous Oxide for the Treatment of Major Depressive Disorder

NCT03869736
View directory record Official record
Conditions
Depression, Major Depressive Disorder
Interventions
Nitrous Oxide, Placebo
Drug
Lead sponsor
Bayside Health
Government
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Jun 27, 2026, 5:48 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparative Effects of Two Anesthetic Techniques on Auditory Brain Response in Children

NCT02830815
View directory record Official record
Conditions
Auditory Brainstem Response
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 18 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Jun 27, 2026, 5:48 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects

NCT01557920
View directory record Official record
Conditions
Airway Complication of Anaesthesia, Healthy
Interventions
Propofol, Sevoflurane
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 12, 2016 · Synced Jun 27, 2026, 5:48 AM EDT
Completed Phase 4 Interventional

General Anesthetics in CAncer REsection Surgery (GA-CARES) Trial

NCT03034096
View directory record Official record
Conditions
Anesthesia, General, Surgical Oncology
Interventions
Propofol, Volatile Agent
Drug
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
1,826 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
5
States / cities
Buffalo, New York • New Hyde Park, New York • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 3, 2025 · Synced Jun 27, 2026, 5:48 AM EDT
Not listed No phase listed Observational

A Prospective Study to Bilaterally Compare a Non-Invasive Cardiac Output Monitor

NCT01678066
View directory record Official record
Conditions
Anesthesiology, Pediatrics, General Surgery, Orthopedics, General Anesthesia, Cardiac Output
Interventions
Bilateral cardiac output
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
1 Month to 8 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2012 · Synced Jun 27, 2026, 5:48 AM EDT
Terminated Phase 4 Interventional Results available

Avoiding Neuromuscular Blockers to Reduce Complications

NCT03962725
View directory record Official record
Conditions
Respiratory Failure, Respiratory Infection, Aspiration Pneumonia, Pneumonitis, Atelectasis, Bronchospasm
Interventions
Neuromuscular Blocking Agents, Anesthetic Adjuncts
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jun 27, 2026, 5:48 AM EDT
Completed No phase listed Observational Results available

Sevoflurane Concentrations in Children

NCT06510803
View directory record Official record
Conditions
Anesthetic, Sevoflurane, Age
Interventions
The washin of sevoflurane in the GE Ohmeda workstation
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
2 Years to 7 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jun 27, 2026, 5:48 AM EDT
Withdrawn Phase 4 Interventional

How Lidocaine Affects Outcomes In Orthopedic Surgery Patients

NCT01179100
View directory record Official record
Conditions
General Anesthesia, Surgeries Requiring A Minimum One Day Hospitalization, Elderly
Interventions
Lidocaine
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 6, 2015 · Synced Jun 27, 2026, 5:48 AM EDT